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The map label for this gene is gap [H]

Identifier: 110680085

GI number: 110680085

Start: 2757540

End: 2758547

Strand: Reverse

Name: gap [H]

Synonym: RD1_2880

Alternate gene names: 110680085

Gene position: 2758547-2757540 (Counterclockwise)

Preceding gene: 110680086

Following gene: 110680084

Centisome position: 66.74

GC content: 60.02

Gene sequence:

>1008_bases
ATGTCCCATCAGGTAGGTATCAACGGCTTTGGACGAATTGGGCGGGGTGTCCTGCGCGCATTGGTCGAAAACAGAATTTC
CGATGTGGAAGTTGTCGCCATCAACGACCTGTCCAGCCCTGAAACGCTGGCGCATCTGTTGAAATACGACAGTGTGCACG
GACGCTTTCAGGGGGATGTTGAAGTGCAGGGCGATGCGCTCATCGTCAATGGCAAGCCGATCCGGGTGAGTGCGTTGCGC
GACCCGGCGGAACTGCCGTGGGGCGACGTGGATGTCGCGATGGAATGCACGGGGTTTTTCACGGCGCGCGATAAGGCCGC
GTTGCATCTCAAGAACGGCTCTGGCCGGGTTCTGATCTCGGCACCCGGGGCGGATGCGGATCGCACCGTTGTGTTTGGCG
TCAATGATCACGAATTGACCAAGGATGATGCGATCGTCTCCAACGCGTCCTGCACGACGAATTGTCTGGCTCCGGTGGCG
GCGGTTCTGGACAAGGCGGTCGGTATCAAAACCGGCTACATGACCACCATCCATGCCTATACCGGCGATCAGCCATCGCA
TGACGCCGCGCACAAAGACCCCTACCGTGGGCGGGCAGCAGCCCTGTCGATGGTACCGACCTCAACAGGGGCCGCCAAGG
CCATCGCGCTGGTTCTGCCGCGCCTTGAGGGGCGTCTTGAAGGGTCCGCAGTGCGGGTCCCGACACCGAATGTATCCCTC
GTGGACCTCAGCTTTGTGCCGGAGAAAGACACGAGCGCCGATGAGATCAACGCCGCGATCAAAGCCGCCGCCGAGGGGCC
GATGCGGGGGGTTCTGTCCTATGAAACGGACCCGATGGTATCCATTGATTTCAACCACGATTCGCATTCGTCCTGCTTTG
CCGCGCCGCAAACCAAAGTGACGCGCGACGGGCTGGTGCGTGTCGTGACGTGGTATGACAATGAGTGGGGTTTTGCCAAT
CGCATGATCGATACTGGACGCAAACTGGCGACACTGGCCAAAAGCTGA

Upstream 100 bases:

>100_bases
AAATCAGGCATTGAAATCTCTGGCGATTTGTGATCGTTAGCGCTAACAGATCAACGGCGCTGGTTGCCAGCACATGCATA
TGCAGTCTCAGGAGGATAGG

Downstream 100 bases:

>100_bases
CCTGAGCCGGTCCGTTTGAACGTCACAGCCATTGGAGAAAGCGACATGCCCCTGAACGAGACGATTGATCGCGTCACCCG
GCGCATTATCGAACGCAGCA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSHQVGINGFGRIGRGVLRALVENRISDVEVVAINDLSSPETLAHLLKYDSVHGRFQGDVEVQGDALIVNGKPIRVSALR
DPAELPWGDVDVAMECTGFFTARDKAALHLKNGSGRVLISAPGADADRTVVFGVNDHELTKDDAIVSNASCTTNCLAPVA
AVLDKAVGIKTGYMTTIHAYTGDQPSHDAAHKDPYRGRAAALSMVPTSTGAAKAIALVLPRLEGRLEGSAVRVPTPNVSL
VDLSFVPEKDTSADEINAAIKAAAEGPMRGVLSYETDPMVSIDFNHDSHSSCFAAPQTKVTRDGLVRVVTWYDNEWGFAN
RMIDTGRKLATLAKS

Sequences:

>Translated_335_residues
MSHQVGINGFGRIGRGVLRALVENRISDVEVVAINDLSSPETLAHLLKYDSVHGRFQGDVEVQGDALIVNGKPIRVSALR
DPAELPWGDVDVAMECTGFFTARDKAALHLKNGSGRVLISAPGADADRTVVFGVNDHELTKDDAIVSNASCTTNCLAPVA
AVLDKAVGIKTGYMTTIHAYTGDQPSHDAAHKDPYRGRAAALSMVPTSTGAAKAIALVLPRLEGRLEGSAVRVPTPNVSL
VDLSFVPEKDTSADEINAAIKAAAEGPMRGVLSYETDPMVSIDFNHDSHSSCFAAPQTKVTRDGLVRVVTWYDNEWGFAN
RMIDTGRKLATLAKS
>Mature_334_residues
SHQVGINGFGRIGRGVLRALVENRISDVEVVAINDLSSPETLAHLLKYDSVHGRFQGDVEVQGDALIVNGKPIRVSALRD
PAELPWGDVDVAMECTGFFTARDKAALHLKNGSGRVLISAPGADADRTVVFGVNDHELTKDDAIVSNASCTTNCLAPVAA
VLDKAVGIKTGYMTTIHAYTGDQPSHDAAHKDPYRGRAAALSMVPTSTGAAKAIALVLPRLEGRLEGSAVRVPTPNVSLV
DLSFVPEKDTSADEINAAIKAAAEGPMRGVLSYETDPMVSIDFNHDSHSSCFAAPQTKVTRDGLVRVVTWYDNEWGFANR
MIDTGRKLATLAKS

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=45.4819277108434, Blast_Score=291, Evalue=5e-79,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=45.4545454545455, Blast_Score=281, Evalue=7e-76,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=51.0703363914373, Blast_Score=314, Evalue=6e-87,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=47.1810089020772, Blast_Score=308, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=49.4082840236686, Blast_Score=299, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=48.8165680473373, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=50.1474926253687, Blast_Score=296, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=50.1474926253687, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=325, Percent_Identity=48.3076923076923, Blast_Score=298, Evalue=9e-82,
Organism=Saccharomyces cerevisiae, GI6321631, Length=325, Percent_Identity=48.6153846153846, Blast_Score=295, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=325, Percent_Identity=47.6923076923077, Blast_Score=290, Evalue=1e-79,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=48.3076923076923, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=48.3076923076923, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=47.6923076923077, Blast_Score=291, Evalue=3e-79,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=47.6923076923077, Blast_Score=291, Evalue=3e-79,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=45.2307692307692, Blast_Score=264, Evalue=6e-71,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35685; Mature: 35553

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQVGINGFGRIGRGVLRALVENRISDVEVVAINDLSSPETLAHLLKYDSVHGRFQGDV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEECCCE
EVQGDALIVNGKPIRVSALRDPAELPWGDVDVAMECTGFFTARDKAALHLKNGSGRVLIS
EEECCEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCEEEEE
APGADADRTVVFGVNDHELTKDDAIVSNASCTTNCLAPVAAVLDKAVGIKTGYMTTIHAY
CCCCCCCCEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TGDQPSHDAAHKDPYRGRAAALSMVPTSTGAAKAIALVLPRLEGRLEGSAVRVPTPNVSL
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCEE
VDLSFVPEKDTSADEINAAIKAAAEGPMRGVLSYETDPMVSIDFNHDSHSSCFAAPQTKV
EEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCEEECCCCCC
TRDGLVRVVTWYDNEWGFANRMIDTGRKLATLAKS
CCCCEEEEEEEECCCCCHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure 
SHQVGINGFGRIGRGVLRALVENRISDVEVVAINDLSSPETLAHLLKYDSVHGRFQGDV
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEECCCE
EVQGDALIVNGKPIRVSALRDPAELPWGDVDVAMECTGFFTARDKAALHLKNGSGRVLIS
EEECCEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCEEEEE
APGADADRTVVFGVNDHELTKDDAIVSNASCTTNCLAPVAAVLDKAVGIKTGYMTTIHAY
CCCCCCCCEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TGDQPSHDAAHKDPYRGRAAALSMVPTSTGAAKAIALVLPRLEGRLEGSAVRVPTPNVSL
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCEE
VDLSFVPEKDTSADEINAAIKAAAEGPMRGVLSYETDPMVSIDFNHDSHSSCFAAPQTKV
EEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCEEECCCCCC
TRDGLVRVVTWYDNEWGFANRMIDTGRKLATLAKS
CCCCEEEEEEEECCCCCHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]