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The map label for this gene is gbsB [H]

Identifier: 110680086

GI number: 110680086

Start: 2758712

End: 2759890

Strand: Reverse

Name: gbsB [H]

Synonym: RD1_2882

Alternate gene names: 110680086

Gene position: 2759890-2758712 (Counterclockwise)

Preceding gene: 110680087

Following gene: 110680085

Centisome position: 66.78

GC content: 64.38

Gene sequence:

>1179_bases
ATGCCACCCTGCGCTTTTGAGAACGGCATGGGGTCAGCCACATTCACTTTTCAAACCGCGGGCCGGGTCACTTTTGGGCG
CGGTGCGCGCGTATCAGCGGCGCAGGCGGTTGCGGCGTTCGGCACCGGGGTCTGTCTGGTGCGCGGGCACTCCGTGGTTT
GGGTGGACGCGCTTGAGGCGGAATTGAGCGCCGCGGGATGCAGCATCCAATCCATTCGCTGTCGGGCGGAGCCGGATATC
GACATGCTGCAAGAGGCTTTGGCGCAGATCAAGGCGGGCCCTGTGGATGTTGTCGTGGCGGTCGGGGGTGGTTCTGTCAT
GGATCTGGGCAAGGCGCTTGCGGCGCTGGCGCCGGGGGATGCGCCGGTACTTGATCATCTGGAGGGTGTTGGGAAAGGCC
TGCCGCTGCGTGCTGCGCCCCTGCCGTTTGTGGCGATCCCAACCACGGCTGGCACGGGCTCGGAAGTCACCAAGAATGCC
GTGATCGGTGTCCCCGGTTCGGGCCGCAAGGTCAGTCTGCGGGATGACAGGATGCTGGCGCGTCTGGCGATTGTCGATCC
TGAGTTGATGGACGATGCCCCGAAAGACGTGACCCTTGCATCCGGTCTTGATGCGCTGGTGCAGGTGATCGAACCCTACC
TCAGCAAACGCAGCAACCCGGTCACGGATGCCCTGTGCCGGGAGGCGATTCCCAAGGCGGCCCATGCGCTGGCGCGACTT
CTGGAAGGCGAAGATGCTCAGGCAAGAGACGACATGGCCTTCGCGAGCCTGTGCGGGGGCATGGCGCTTGCGAACGCGGG
TCTGGGGGCTGTGCACGGCCTTGCTGGTGCCATTGGCGGGCGCAGCGGTGCGCCGCATGGGTTGATCTGCGGCAGGCTTC
TGGGCGGTGTTTTGCAGGCGAACCGGGCGGCCTTGTCAGGATTGAACCAACAGGCAGCCCGCTTTGATGAGGTAGCGGCG
CATCTGTCGCAAGCCTTTGGAATCCGGACGCCAATTGATGCGGCAGCCTGGGCGGACATGCTGGACAGTTGGGGTCTGGC
GCGGCTGGGGCGTTGGATGACCCCCGATGTGTGCCTCAGCACGGTTGCGCAGGATGCAGCCGTCAGTTCGTCGATGCAGG
CCAATCCCTGCACCCTGTCAGAGGCGGATTTGGTCCGTCTGATCAAGGCCGTATTATAG

Upstream 100 bases:

>100_bases
GCCGGATTTGCCGCAAGCTGGGCTCTTGAAAAGACCTTTGCGCCGCAGATGGACGCGGCTCTGCGCGACAGGAAATACGC
AGCCTGGAAGCGGGCGGTGG

Downstream 100 bases:

>100_bases
CAACGTCCGGGCTGCGTGACACCGGGCCGGCAAGCTATGTTCACAGAGCAAGGCAGGCCCGGTAAAATCAGGCATTGAAA
TCTCTGGCGATTTGTGATCG

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MPPCAFENGMGSATFTFQTAGRVTFGRGARVSAAQAVAAFGTGVCLVRGHSVVWVDALEAELSAAGCSIQSIRCRAEPDI
DMLQEALAQIKAGPVDVVVAVGGGSVMDLGKALAALAPGDAPVLDHLEGVGKGLPLRAAPLPFVAIPTTAGTGSEVTKNA
VIGVPGSGRKVSLRDDRMLARLAIVDPELMDDAPKDVTLASGLDALVQVIEPYLSKRSNPVTDALCREAIPKAAHALARL
LEGEDAQARDDMAFASLCGGMALANAGLGAVHGLAGAIGGRSGAPHGLICGRLLGGVLQANRAALSGLNQQAARFDEVAA
HLSQAFGIRTPIDAAAWADMLDSWGLARLGRWMTPDVCLSTVAQDAAVSSSMQANPCTLSEADLVRLIKAVL

Sequences:

>Translated_392_residues
MPPCAFENGMGSATFTFQTAGRVTFGRGARVSAAQAVAAFGTGVCLVRGHSVVWVDALEAELSAAGCSIQSIRCRAEPDI
DMLQEALAQIKAGPVDVVVAVGGGSVMDLGKALAALAPGDAPVLDHLEGVGKGLPLRAAPLPFVAIPTTAGTGSEVTKNA
VIGVPGSGRKVSLRDDRMLARLAIVDPELMDDAPKDVTLASGLDALVQVIEPYLSKRSNPVTDALCREAIPKAAHALARL
LEGEDAQARDDMAFASLCGGMALANAGLGAVHGLAGAIGGRSGAPHGLICGRLLGGVLQANRAALSGLNQQAARFDEVAA
HLSQAFGIRTPIDAAAWADMLDSWGLARLGRWMTPDVCLSTVAQDAAVSSSMQANPCTLSEADLVRLIKAVL
>Mature_391_residues
PPCAFENGMGSATFTFQTAGRVTFGRGARVSAAQAVAAFGTGVCLVRGHSVVWVDALEAELSAAGCSIQSIRCRAEPDID
MLQEALAQIKAGPVDVVVAVGGGSVMDLGKALAALAPGDAPVLDHLEGVGKGLPLRAAPLPFVAIPTTAGTGSEVTKNAV
IGVPGSGRKVSLRDDRMLARLAIVDPELMDDAPKDVTLASGLDALVQVIEPYLSKRSNPVTDALCREAIPKAAHALARLL
EGEDAQARDDMAFASLCGGMALANAGLGAVHGLAGAIGGRSGAPHGLICGRLLGGVLQANRAALSGLNQQAARFDEVAAH
LSQAFGIRTPIDAAAWADMLDSWGLARLGRWMTPDVCLSTVAQDAAVSSSMQANPCTLSEADLVRLIKAVL

Specific function: Essential for the utilization of choline as a precursor [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=229, Percent_Identity=31.8777292576419, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87082107, Length=227, Percent_Identity=38.7665198237885, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI48994951, Length=220, Percent_Identity=37.2727272727273, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789163, Length=227, Percent_Identity=36.5638766519824, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787493, Length=317, Percent_Identity=29.3375394321767, Blast_Score=111, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17537053, Length=249, Percent_Identity=32.1285140562249, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321181, Length=251, Percent_Identity=37.0517928286853, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24657991, Length=308, Percent_Identity=25.974025974026, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40036; Mature: 39905

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPCAFENGMGSATFTFQTAGRVTFGRGARVSAAQAVAAFGTGVCLVRGHSVVWVDALEA
CCCCCCCCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHCCCEEEEECCCEEEEEHHHH
ELSAAGCSIQSIRCRAEPDIDMLQEALAQIKAGPVDVVVAVGGGSVMDLGKALAALAPGD
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCC
APVLDHLEGVGKGLPLRAAPLPFVAIPTTAGTGSEVTKNAVIGVPGSGRKVSLRDDRMLA
CHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHCCCEEECCCCCCEEEECHHHHHH
RLAIVDPELMDDAPKDVTLASGLDALVQVIEPYLSKRSNPVTDALCREAIPKAAHALARL
HHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LEGEDAQARDDMAFASLCGGMALANAGLGAVHGLAGAIGGRSGAPHGLICGRLLGGVLQA
HCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NRAALSGLNQQAARFDEVAAHLSQAFGIRTPIDAAAWADMLDSWGLARLGRWMTPDVCLS
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHH
TVAQDAAVSSSMQANPCTLSEADLVRLIKAVL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
PPCAFENGMGSATFTFQTAGRVTFGRGARVSAAQAVAAFGTGVCLVRGHSVVWVDALEA
CCCCCCCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHCCCEEEEECCCEEEEEHHHH
ELSAAGCSIQSIRCRAEPDIDMLQEALAQIKAGPVDVVVAVGGGSVMDLGKALAALAPGD
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCC
APVLDHLEGVGKGLPLRAAPLPFVAIPTTAGTGSEVTKNAVIGVPGSGRKVSLRDDRMLA
CHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHCCCEEECCCCCCEEEECHHHHHH
RLAIVDPELMDDAPKDVTLASGLDALVQVIEPYLSKRSNPVTDALCREAIPKAAHALARL
HHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LEGEDAQARDDMAFASLCGGMALANAGLGAVHGLAGAIGGRSGAPHGLICGRLLGGVLQA
HCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NRAALSGLNQQAARFDEVAAHLSQAFGIRTPIDAAAWADMLDSWGLARLGRWMTPDVCLS
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHH
TVAQDAAVSSSMQANPCTLSEADLVRLIKAVL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8752328; 9384377 [H]