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The map label for this gene is degS [H]

Identifier: 110680017

GI number: 110680017

Start: 2678435

End: 2679868

Strand: Direct

Name: degS [H]

Synonym: RD1_2810

Alternate gene names: 110680017

Gene position: 2678435-2679868 (Clockwise)

Preceding gene: 110680013

Following gene: 110680018

Centisome position: 64.8

GC content: 61.23

Gene sequence:

>1434_bases
ATGATGCGGTTCCTGCCTGTTTTCCGGCCAAGCTACGCGCAAAAGCTGTCGCTTTTGGCCACGGTGCCCCTGATTGCGGC
GGTGGCGGCCATTGCTGCTCTTGTGGCGTTTCAGTCGCGCGCCCTCGCCGAACGGGAAGTCCGCGCGCTGGAAACCCAGC
TGATCCAGGCAAAGAAAGCCGAATTGCGCAATTACATCACGCAGGCGCGCAACGGATTCTACTTTATCTACGGCAATGCG
GCACCCGACGATTCCGATGCCAAGAACCAGGTCGCACAGATCCTGTCGGCCATGATCTATGGCACCGATGGTTTCTTTTT
CGTCTATGATTATGACGGCAACAGTCTGGTCAGCCCGCGCCAGACCGACCGGATCAATAAAAACTGGATGGATGAGACCG
ATACCGAAGGCACACCCGTCGTGGCCCGTCTGATCGAAATCGCGCGGCAAGGGGATGGATATCTGACCCATCAATGGCCC
AAACCCTCGACCGGGGAAGACGCGCGGATGATCACCTATGTCACCAGCTTTCCCAGTTGGCGATGGGCGGTCGGCACGGG
CGTGTTCATTGACGACGTATTGGCCACGGTGGCCATCGCGCGTGCCGAGGTTGAGGCGCGCGTGCAGCAGACGTTCATCT
ACATCGGGGCGATCACACTGGCCGCCCTGCTGGTCGTTTTCCTGACCGGCATGGTGCTGAACATCCGCGAACGCCGCCTT
GCGGATGCCAAGCTGAAACGGCTGACCCAGCGGGTTCTGGACGCACAGGAAGAAGAACGCGGACGCGTGGCGCGTGAATT
GCACGATGGCATCAGCCAGATCCTCGTCGGCGTCCGCTATGCGCTGGACACGGCCCGGCGCAAGCTGGAACGCGGTGATC
CCACCGCGGCGGAGCCTTTGGGCAAGGGCATCGAAACACTGGGCGAGGCGATCTCCGAGGTGCGCCGCATCAGCCGCGAT
CTGCGTCCCGGCATGTTGGATGATCTCGGCCTTGGGCCGGCGATAAAGAACCTGACGGATGCCTTTGGCGAACGCACGGG
TCTGGCCACTGAGTTCACGACAGTGGTTTTCCGCAACAGGCTCGATTCCGACGCGAAGATTGCGCTCTACCGTATCGCGC
AGGAAGCACTCACGAATATCGAACGCCATGCGCGCGCCACGCGGGTCAGCGTTGATCTGCGCGGTCACGCGCGCGGTGCG
ACGCTGCGGATTGAGGACAACGGATGCGGGTTGAAAAACGGATCAACGCACCCCTCTCAAGGCCTTGGCCTGCGCAACAT
GCAGGAAAGAGTTGAGCAACTGGAAGGTGAGCTCAACGTCTACACCACCCGCTCGGGCACGGGCACGGTTGTTGAGGTGA
GCGTTCCGCTGTCCCATCTGCTGCCCCCCGAACCCGAACCCCCACAGCCCAATCAGCAAAAGCAGACCGCATGA

Upstream 100 bases:

>100_bases
CGAGTTATTCTGCATCACACACCACAGACGCGCAGTGATTCTGGCCAAAGCGCGCCTTGCGGGTCTTTGATTCGCGCAAC
TTTCAACGTAGCAATAACGG

Downstream 100 bases:

>100_bases
CACAGACATCCCCGGACCCGATCAAGGTATTGATCATTGATGACCATCCGATGGTCGCCGAAGGAATCCAGTCGATTCTG
GAAAGCTACGAGGATCTGAG

Product: sensor protein degS

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMRFLPVFRPSYAQKLSLLATVPLIAAVAAIAALVAFQSRALAEREVRALETQLIQAKKAELRNYITQARNGFYFIYGNA
APDDSDAKNQVAQILSAMIYGTDGFFFVYDYDGNSLVSPRQTDRINKNWMDETDTEGTPVVARLIEIARQGDGYLTHQWP
KPSTGEDARMITYVTSFPSWRWAVGTGVFIDDVLATVAIARAEVEARVQQTFIYIGAITLAALLVVFLTGMVLNIRERRL
ADAKLKRLTQRVLDAQEEERGRVARELHDGISQILVGVRYALDTARRKLERGDPTAAEPLGKGIETLGEAISEVRRISRD
LRPGMLDDLGLGPAIKNLTDAFGERTGLATEFTTVVFRNRLDSDAKIALYRIAQEALTNIERHARATRVSVDLRGHARGA
TLRIEDNGCGLKNGSTHPSQGLGLRNMQERVEQLEGELNVYTTRSGTGTVVEVSVPLSHLLPPEPEPPQPNQQKQTA

Sequences:

>Translated_477_residues
MMRFLPVFRPSYAQKLSLLATVPLIAAVAAIAALVAFQSRALAEREVRALETQLIQAKKAELRNYITQARNGFYFIYGNA
APDDSDAKNQVAQILSAMIYGTDGFFFVYDYDGNSLVSPRQTDRINKNWMDETDTEGTPVVARLIEIARQGDGYLTHQWP
KPSTGEDARMITYVTSFPSWRWAVGTGVFIDDVLATVAIARAEVEARVQQTFIYIGAITLAALLVVFLTGMVLNIRERRL
ADAKLKRLTQRVLDAQEEERGRVARELHDGISQILVGVRYALDTARRKLERGDPTAAEPLGKGIETLGEAISEVRRISRD
LRPGMLDDLGLGPAIKNLTDAFGERTGLATEFTTVVFRNRLDSDAKIALYRIAQEALTNIERHARATRVSVDLRGHARGA
TLRIEDNGCGLKNGSTHPSQGLGLRNMQERVEQLEGELNVYTTRSGTGTVVEVSVPLSHLLPPEPEPPQPNQQKQTA
>Mature_477_residues
MMRFLPVFRPSYAQKLSLLATVPLIAAVAAIAALVAFQSRALAEREVRALETQLIQAKKAELRNYITQARNGFYFIYGNA
APDDSDAKNQVAQILSAMIYGTDGFFFVYDYDGNSLVSPRQTDRINKNWMDETDTEGTPVVARLIEIARQGDGYLTHQWP
KPSTGEDARMITYVTSFPSWRWAVGTGVFIDDVLATVAIARAEVEARVQQTFIYIGAITLAALLVVFLTGMVLNIRERRL
ADAKLKRLTQRVLDAQEEERGRVARELHDGISQILVGVRYALDTARRKLERGDPTAAEPLGKGIETLGEAISEVRRISRD
LRPGMLDDLGLGPAIKNLTDAFGERTGLATEFTTVVFRNRLDSDAKIALYRIAQEALTNIERHARATRVSVDLRGHARGA
TLRIEDNGCGLKNGSTHPSQGLGLRNMQERVEQLEGELNVYTTRSGTGTVVEVSVPLSHLLPPEPEPPQPNQQKQTA

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=216, Percent_Identity=35.1851851851852, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788812, Length=198, Percent_Identity=29.7979797979798, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787474, Length=244, Percent_Identity=26.2295081967213, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52785; Mature: 52785

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRFLPVFRPSYAQKLSLLATVPLIAAVAAIAALVAFQSRALAEREVRALETQLIQAKKA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRNYITQARNGFYFIYGNAAPDDSDAKNQVAQILSAMIYGTDGFFFVYDYDGNSLVSPR
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
QTDRINKNWMDETDTEGTPVVARLIEIARQGDGYLTHQWPKPSTGEDARMITYVTSFPSW
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEECCCCC
RWAVGTGVFIDDVLATVAIARAEVEARVQQTFIYIGAITLAALLVVFLTGMVLNIRERRL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAKLKRLTQRVLDAQEEERGRVARELHDGISQILVGVRYALDTARRKLERGDPTAAEPL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GKGIETLGEAISEVRRISRDLRPGMLDDLGLGPAIKNLTDAFGERTGLATEFTTVVFRNR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHC
LDSDAKIALYRIAQEALTNIERHARATRVSVDLRGHARGATLRIEDNGCGLKNGSTHPSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
GLGLRNMQERVEQLEGELNVYTTRSGTGTVVEVSVPLSHLLPPEPEPPQPNQQKQTA
CCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMRFLPVFRPSYAQKLSLLATVPLIAAVAAIAALVAFQSRALAEREVRALETQLIQAKKA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRNYITQARNGFYFIYGNAAPDDSDAKNQVAQILSAMIYGTDGFFFVYDYDGNSLVSPR
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
QTDRINKNWMDETDTEGTPVVARLIEIARQGDGYLTHQWPKPSTGEDARMITYVTSFPSW
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEECCCCC
RWAVGTGVFIDDVLATVAIARAEVEARVQQTFIYIGAITLAALLVVFLTGMVLNIRERRL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAKLKRLTQRVLDAQEEERGRVARELHDGISQILVGVRYALDTARRKLERGDPTAAEPL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GKGIETLGEAISEVRRISRDLRPGMLDDLGLGPAIKNLTDAFGERTGLATEFTTVVFRNR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHC
LDSDAKIALYRIAQEALTNIERHARATRVSVDLRGHARGATLRIEDNGCGLKNGSTHPSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
GLGLRNMQERVEQLEGELNVYTTRSGTGTVVEVSVPLSHLLPPEPEPPQPNQQKQTA
CCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]