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The map label for this gene is phoR [H]

Identifier: 110679868

GI number: 110679868

Start: 2521030

End: 2522073

Strand: Direct

Name: phoR [H]

Synonym: RD1_2641

Alternate gene names: 110679868

Gene position: 2521030-2522073 (Clockwise)

Preceding gene: 110679867

Following gene: 110679869

Centisome position: 61.0

GC content: 61.88

Gene sequence:

>1044_bases
ATGGCAGAGGCAATTCACGAGGTGCTCGCGGCCCTGCCGATGCCGGTTTTGGCCATAGGTGGCAGCGAACGCATCGTGTC
GGCAAATGATGCGGCCAAGGCGCTGCTCGGGCAGGGGGTTTCCGGGCGCCATTACGTCACCTTTTTGCGCCAGCCACAGC
TGATTGAAACCATTGCCGCCGTGTTGCAGGACAGCCAGCCGCGCGTGTCGCAGTATTTCTCCAGCGACGGAATCGAGGAT
ACCACCTTTCGTGTCACCGTTGGGGTGCTGGCGAACATGCGCGTTGTGTTGCTGAGTTTTCAGGACGTCAGTCATCTGGA
ACAGGCGGATCAGATGCGCCGGGACTTCGTTGCCAATGTCAGTCACGAGTTGCGCACGCCGCTTACCGCACTGATGGGGT
TCATCGAAACCCTGCGCGGGCCTGCGCGCGAGGATGCGGCCGCACGGGACAGGTTTCTTGACATCATGGAGGGCGAAGCC
GGACGGATGAACCGGCTCGTGGGGGATCTGCTCTCCCTCAGCCGGGTCGAGGGAAACCAGCGGGTGCGCCCGCAAGATCG
CGTGAACCTCAGCGATGTGGTGCAATCTGTGGCGCGCACCCTGGCACCGCTGGCGAATGATACGTCGGTGGTGCTCGAAT
GCGACCTTCCGCAGCAACCGGTGATCCTGATCGGAGATGCTGACCAGCTGATGCAAGTCATCACGAACCTTGTGGAAAAT
GCCGTCAAATACGGCGGGTCCGGTGGGCGGGTTGCAATCAAACTGACCGAAGTTGCACGGGATACATCGCTGCGCGCGCC
GGGCGTTCTGATCAGCGTAACCGATTTCGGACCCGGCATTGATCCGGTGCATCTGCCGCGCCTGACCGAACGGTTTTACC
GCGCTGACAGCCACCGCAGCAGGGCTTTGGGGGGCACGGGCCTGGGGCTGGCCATCGTCAAACACATCATAAACCGGCAT
CGCGGGCGTTTGCGCATCGACAGCGAACTGGGGCAGGGGTCCACGTTCACCGTTGTCCTGCCGCTTGACCTTAACAGCGC
CTGA

Upstream 100 bases:

>100_bases
TCGTGTCTCTGTCGGGCTCGAAGACCCCGATAATCTCTGCGCGATCTTTACGGAAGCGGTCAGCGCGGCTGTGGCCCCCT
AGCAAGGATTAAAAACACCC

Downstream 100 bases:

>100_bases
AACGAACCCACTTCGGGTCCGCGCAGCAACATCGCAGTTTATTTTCGTCATAAAATCAGATAGATATGTTATTTTCTGCC
ATGTCATAAAACCGTTACAA

Product: phosphate regulon sensor protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAEAIHEVLAALPMPVLAIGGSERIVSANDAAKALLGQGVSGRHYVTFLRQPQLIETIAAVLQDSQPRVSQYFSSDGIED
TTFRVTVGVLANMRVVLLSFQDVSHLEQADQMRRDFVANVSHELRTPLTALMGFIETLRGPAREDAAARDRFLDIMEGEA
GRMNRLVGDLLSLSRVEGNQRVRPQDRVNLSDVVQSVARTLAPLANDTSVVLECDLPQQPVILIGDADQLMQVITNLVEN
AVKYGGSGGRVAIKLTEVARDTSLRAPGVLISVTDFGPGIDPVHLPRLTERFYRADSHRSRALGGTGLGLAIVKHIINRH
RGRLRIDSELGQGSTFTVVLPLDLNSA

Sequences:

>Translated_347_residues
MAEAIHEVLAALPMPVLAIGGSERIVSANDAAKALLGQGVSGRHYVTFLRQPQLIETIAAVLQDSQPRVSQYFSSDGIED
TTFRVTVGVLANMRVVLLSFQDVSHLEQADQMRRDFVANVSHELRTPLTALMGFIETLRGPAREDAAARDRFLDIMEGEA
GRMNRLVGDLLSLSRVEGNQRVRPQDRVNLSDVVQSVARTLAPLANDTSVVLECDLPQQPVILIGDADQLMQVITNLVEN
AVKYGGSGGRVAIKLTEVARDTSLRAPGVLISVTDFGPGIDPVHLPRLTERFYRADSHRSRALGGTGLGLAIVKHIINRH
RGRLRIDSELGQGSTFTVVLPLDLNSA
>Mature_346_residues
AEAIHEVLAALPMPVLAIGGSERIVSANDAAKALLGQGVSGRHYVTFLRQPQLIETIAAVLQDSQPRVSQYFSSDGIEDT
TFRVTVGVLANMRVVLLSFQDVSHLEQADQMRRDFVANVSHELRTPLTALMGFIETLRGPAREDAAARDRFLDIMEGEAG
RMNRLVGDLLSLSRVEGNQRVRPQDRVNLSDVVQSVARTLAPLANDTSVVLECDLPQQPVILIGDADQLMQVITNLVENA
VKYGGSGGRVAIKLTEVARDTSLRAPGVLISVTDFGPGIDPVHLPRLTERFYRADSHRSRALGGTGLGLAIVKHIINRHR
GRLRIDSELGQGSTFTVVLPLDLNSA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=247, Percent_Identity=40.4858299595142, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=34.5679012345679, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=34.5833333333333, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=31.8897637795276, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=28.2157676348548, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=31.9672131147541, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=33.469387755102, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=30, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=29.3103448275862, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788549, Length=345, Percent_Identity=25.5072463768116, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082128, Length=259, Percent_Identity=27.7992277992278, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=28.2868525896414, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790551, Length=228, Percent_Identity=32.8947368421053, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=26.9911504424779, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789403, Length=207, Percent_Identity=31.8840579710145, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=30.3501945525292, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=31.5352697095436, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=32.8063241106719, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=28.8617886178862, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=26.1904761904762, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=75, Percent_Identity=42.6666666666667, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37689; Mature: 37558

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAIHEVLAALPMPVLAIGGSERIVSANDAAKALLGQGVSGRHYVTFLRQPQLIETIAA
CHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
VLQDSQPRVSQYFSSDGIEDTTFRVTVGVLANMRVVLLSFQDVSHLEQADQMRRDFVANV
HHCCCCHHHHHHHHCCCCCCCCCEEHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
SHELRTPLTALMGFIETLRGPAREDAAARDRFLDIMEGEAGRMNRLVGDLLSLSRVEGNQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
RVRPQDRVNLSDVVQSVARTLAPLANDTSVVLECDLPQQPVILIGDADQLMQVITNLVEN
CCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHH
AVKYGGSGGRVAIKLTEVARDTSLRAPGVLISVTDFGPGIDPVHLPRLTERFYRADSHRS
HHHHCCCCCEEEEEEEHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHH
RALGGTGLGLAIVKHIINRHRGRLRIDSELGQGSTFTVVLPLDLNSA
HCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
AEAIHEVLAALPMPVLAIGGSERIVSANDAAKALLGQGVSGRHYVTFLRQPQLIETIAA
HHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
VLQDSQPRVSQYFSSDGIEDTTFRVTVGVLANMRVVLLSFQDVSHLEQADQMRRDFVANV
HHCCCCHHHHHHHHCCCCCCCCCEEHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
SHELRTPLTALMGFIETLRGPAREDAAARDRFLDIMEGEAGRMNRLVGDLLSLSRVEGNQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
RVRPQDRVNLSDVVQSVARTLAPLANDTSVVLECDLPQQPVILIGDADQLMQVITNLVEN
CCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHH
AVKYGGSGGRVAIKLTEVARDTSLRAPGVLISVTDFGPGIDPVHLPRLTERFYRADSHRS
HHHHCCCCCEEEEEEEHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHH
RALGGTGLGLAIVKHIINRHRGRLRIDSELGQGSTFTVVLPLDLNSA
HCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]