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The map label for this gene is cfa [H]

Identifier: 110679556

GI number: 110679556

Start: 2191301

End: 2192509

Strand: Direct

Name: cfa [H]

Synonym: RD1_2296

Alternate gene names: 110679556

Gene position: 2191301-2192509 (Clockwise)

Preceding gene: 110679555

Following gene: 110679557

Centisome position: 53.02

GC content: 55.67

Gene sequence:

>1209_bases
ATGATCCTGACATCGACAGACGGGCAGACCGACTTGCCGCGCTACTTTGCGCAGAGCTTTCAAGTGGCCCAGAAGATCAA
GTCGGGGCGTCTCGATATCATCTTGCCGGACGGGCGGACCTTCTCGGCCAGCGGCTCAGAGCCCGGCCCGATTGCCGTGC
TCGAAGTCAAAAACACGGATCTTTTCGCGCGTCTTGTGCGCGATGGATATGTCGGGTTTTCCGAAGCCTATATGGACGAT
TGGTGGTCGACGCCCGATCTGCAAGCCTTCATGGACCTTGTGAACAGCGACAATGATGACATGTACAACGGGTATCCCGG
CCAGAAGCTGGTGCAACTGTTCGAAAAGCTTCGGTTCTGGCTGCAACGCAATCACAAGGCGCAGGCGCGCAAGAACATCA
GCTATCACTATGATCTGGGCAATGATTTTTACGGTTTGTGGCTGGATGACAGCATGACCTATTCCTCGGCCCTGTTTGAA
ACCGGGCAGGAGAGCCTCGAAGCGGCGCAAACCGCGAAATACAAGCTGATGGTCGACGAAATGGGTGCAAAACCCGGCGA
CCATATCCTGGAGATTGGCTGCGGGTGGGGCGGCTTTGCCGAATACGCCGCAAAGGAGCGCGGCCTGCGGGTGACCTGCC
TCACGATCAGCGAAGAACAGTTTAAATACGCCAAGGAACGGATTGAAAAGGCTGGGCTTTCTGATCTGGTGGAATTCAAG
TTGCAAGACTATCGGGATGAAAGCGGGTCCTATGACGGTATTGCGAGCATCGAGATGTTCGAAGCGGTGGGCGAAAAATA
CTGGCCGACCTATTTCAGCAAGGTCCGCGACAGGCTCAAACCGGGCAAATCCGCCACACTGCAGATCATCACGGTCGCTG
ATGATCGCTGGGAAGCCTATCGTAACGACGTCGATTTCATCCAGAAATATATCTTTCCCGGCGGCATGCTGCCCAGTCCA
ACCGCGCTGAAGGATCAGGTGGTGCGTGCGGGCATGGGGGTCGAACGCTCCGTCGAATTCGGTCAAAGCTATGCGATCAC
GCTTAAGCGCTGGCATGAGACATTCAATGAGAAATGGGATCAGGTCAGCGCGATGGGCTTTGATGAACGGTTCCGGCGCA
TGTGGAACTATTATCTGACGTCCTGTGCGGCGGCCTTCGAAACCGCCAATTGCGATGTGACGCAGATCACGATCACACGT
CCGGCCTGA

Upstream 100 bases:

>100_bases
TATGAAAATAGAGGGTTTTAAAACTTTGAAAGGCTTGATCACAGCCCTAACTCTGTCCTAATAAACTGTTAACTAACGGC
AAGAAACGAGCATTTCATTT

Downstream 100 bases:

>100_bases
CCCCGCGCGCAAAAGTTGCCACGCTTGTGCCTTAGTTTTTACACGCCTCAGTGATAGACCCGAACCACCCTCGGCTTCAT
GAACAGTCGGGGGAGAGGTT

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MILTSTDGQTDLPRYFAQSFQVAQKIKSGRLDIILPDGRTFSASGSEPGPIAVLEVKNTDLFARLVRDGYVGFSEAYMDD
WWSTPDLQAFMDLVNSDNDDMYNGYPGQKLVQLFEKLRFWLQRNHKAQARKNISYHYDLGNDFYGLWLDDSMTYSSALFE
TGQESLEAAQTAKYKLMVDEMGAKPGDHILEIGCGWGGFAEYAAKERGLRVTCLTISEEQFKYAKERIEKAGLSDLVEFK
LQDYRDESGSYDGIASIEMFEAVGEKYWPTYFSKVRDRLKPGKSATLQIITVADDRWEAYRNDVDFIQKYIFPGGMLPSP
TALKDQVVRAGMGVERSVEFGQSYAITLKRWHETFNEKWDQVSAMGFDERFRRMWNYYLTSCAAAFETANCDVTQITITR
PA

Sequences:

>Translated_402_residues
MILTSTDGQTDLPRYFAQSFQVAQKIKSGRLDIILPDGRTFSASGSEPGPIAVLEVKNTDLFARLVRDGYVGFSEAYMDD
WWSTPDLQAFMDLVNSDNDDMYNGYPGQKLVQLFEKLRFWLQRNHKAQARKNISYHYDLGNDFYGLWLDDSMTYSSALFE
TGQESLEAAQTAKYKLMVDEMGAKPGDHILEIGCGWGGFAEYAAKERGLRVTCLTISEEQFKYAKERIEKAGLSDLVEFK
LQDYRDESGSYDGIASIEMFEAVGEKYWPTYFSKVRDRLKPGKSATLQIITVADDRWEAYRNDVDFIQKYIFPGGMLPSP
TALKDQVVRAGMGVERSVEFGQSYAITLKRWHETFNEKWDQVSAMGFDERFRRMWNYYLTSCAAAFETANCDVTQITITR
PA
>Mature_402_residues
MILTSTDGQTDLPRYFAQSFQVAQKIKSGRLDIILPDGRTFSASGSEPGPIAVLEVKNTDLFARLVRDGYVGFSEAYMDD
WWSTPDLQAFMDLVNSDNDDMYNGYPGQKLVQLFEKLRFWLQRNHKAQARKNISYHYDLGNDFYGLWLDDSMTYSSALFE
TGQESLEAAQTAKYKLMVDEMGAKPGDHILEIGCGWGGFAEYAAKERGLRVTCLTISEEQFKYAKERIEKAGLSDLVEFK
LQDYRDESGSYDGIASIEMFEAVGEKYWPTYFSKVRDRLKPGKSATLQIITVADDRWEAYRNDVDFIQKYIFPGGMLPSP
TALKDQVVRAGMGVERSVEFGQSYAITLKRWHETFNEKWDQVSAMGFDERFRRMWNYYLTSCAAAFETANCDVTQITITR
PA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=367, Percent_Identity=37.3297002724796, Blast_Score=209, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI133904226, Length=389, Percent_Identity=35.73264781491, Blast_Score=238, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45928; Mature: 45928

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTSTDGQTDLPRYFAQSFQVAQKIKSGRLDIILPDGRTFSASGSEPGPIAVLEVKNTD
CEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCCCCEEEEEECCHH
LFARLVRDGYVGFSEAYMDDWWSTPDLQAFMDLVNSDNDDMYNGYPGQKLVQLFEKLRFW
HHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LQRNHKAQARKNISYHYDLGNDFYGLWLDDSMTYSSALFETGQESLEAAQTAKYKLMVDE
HHCCCHHHHHCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEHHH
MGAKPGDHILEIGCGWGGFAEYAAKERGLRVTCLTISEEQFKYAKERIEKAGLSDLVEFK
HCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHCCHHHHHHHH
LQDYRDESGSYDGIASIEMFEAVGEKYWPTYFSKVRDRLKPGKSATLQIITVADDRWEAY
HHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHH
RNDVDFIQKYIFPGGMLPSPTALKDQVVRAGMGVERSVEFGQSYAITLKRWHETFNEKWD
HCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCHHEEHHHHHHHHHHHHHH
QVSAMGFDERFRRMWNYYLTSCAAAFETANCDVTQITITRPA
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MILTSTDGQTDLPRYFAQSFQVAQKIKSGRLDIILPDGRTFSASGSEPGPIAVLEVKNTD
CEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCCCCEEEEEECCHH
LFARLVRDGYVGFSEAYMDDWWSTPDLQAFMDLVNSDNDDMYNGYPGQKLVQLFEKLRFW
HHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LQRNHKAQARKNISYHYDLGNDFYGLWLDDSMTYSSALFETGQESLEAAQTAKYKLMVDE
HHCCCHHHHHCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEHHH
MGAKPGDHILEIGCGWGGFAEYAAKERGLRVTCLTISEEQFKYAKERIEKAGLSDLVEFK
HCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHCCHHHHHHHH
LQDYRDESGSYDGIASIEMFEAVGEKYWPTYFSKVRDRLKPGKSATLQIITVADDRWEAY
HHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHH
RNDVDFIQKYIFPGGMLPSPTALKDQVVRAGMGVERSVEFGQSYAITLKRWHETFNEKWD
HCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCHHEEHHHHHHHHHHHHHH
QVSAMGFDERFRRMWNYYLTSCAAAFETANCDVTQITITRPA
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]