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The map label for this gene is cobO [H]

Identifier: 110679455

GI number: 110679455

Start: 2079488

End: 2080096

Strand: Reverse

Name: cobO [H]

Synonym: RD1_2181

Alternate gene names: 110679455

Gene position: 2080096-2079488 (Counterclockwise)

Preceding gene: 110679463

Following gene: 110679454

Centisome position: 50.33

GC content: 54.35

Gene sequence:

>609_bases
ATGTCTGACGAAAACGAACGTCACAACGCCAAGATGCGCAAGATCAAAGCGGCACGCGACAAGATGATGGAGCAAAAGAC
CGAACAAAAGGGTCTCATCATGGTGCATACCGGGAAGGGCAAAGGTAAGTCATCCTCCGGCTTCGGGATGATCATGCGCT
GCATTTCGCACAAGATTCCCTGCGCCGTGGTCCAGTTCATCAAGGGCAACTGGGACACGGGCGAGAAGTCGTTCCTGCGC
GACAATTATGCGGATGAATGCCGGTTTTTCGTCTCCGGCGAAGGGTTTACATGGGAAACGCAGGACCGGGCGCGCGACAT
TGCGGCGGCGGAAAATGGCTGGCGGATCGCGAAAGAGCAAATCCTTGATCCCGACATTCAATTCGTACTGCTGGATGAGA
TAAACATCGCGCTGCGTTATGACTATCTGAACATCGACGAGGTGGTCGAGTTTCTGTTGACGCAAAAGCCACACATGACC
CACGTCTGCCTGACCGGGCGCAATGCCAAGCCCGAACTGATTGAGGCCGCCGATCTCGTGACCGAGATGACCTTGGTGAA
ACACCCGTTCAAAGACGGTGTCGTTGCCCAAAAAGGCATCGAGTTTTAG

Upstream 100 bases:

>100_bases
GAATTATCCCGCCCGGTGCTGCAAATTCGATCCAGTGGTGGTTGACCCTGCTCAGCGGGAATGCACTAACTGCGCCAACA
CAAGCACGGGGATTTCCAGC

Downstream 100 bases:

>100_bases
GGTAACGCGCATGGGCCGCGCGATCATGCTGCAGGGCACAGGCTCTGATGTCGGCAAGTCACTTTTGGTGGCAGGGCTTT
GCCGCGCTGCCAAGCGTCGC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSDENERHNAKMRKIKAARDKMMEQKTEQKGLIMVHTGKGKGKSSSGFGMIMRCISHKIPCAVVQFIKGNWDTGEKSFLR
DNYADECRFFVSGEGFTWETQDRARDIAAAENGWRIAKEQILDPDIQFVLLDEINIALRYDYLNIDEVVEFLLTQKPHMT
HVCLTGRNAKPELIEAADLVTEMTLVKHPFKDGVVAQKGIEF

Sequences:

>Translated_202_residues
MSDENERHNAKMRKIKAARDKMMEQKTEQKGLIMVHTGKGKGKSSSGFGMIMRCISHKIPCAVVQFIKGNWDTGEKSFLR
DNYADECRFFVSGEGFTWETQDRARDIAAAENGWRIAKEQILDPDIQFVLLDEINIALRYDYLNIDEVVEFLLTQKPHMT
HVCLTGRNAKPELIEAADLVTEMTLVKHPFKDGVVAQKGIEF
>Mature_201_residues
SDENERHNAKMRKIKAARDKMMEQKTEQKGLIMVHTGKGKGKSSSGFGMIMRCISHKIPCAVVQFIKGNWDTGEKSFLRD
NYADECRFFVSGEGFTWETQDRARDIAAAENGWRIAKEQILDPDIQFVLLDEINIALRYDYLNIDEVVEFLLTQKPHMTH
VCLTGRNAKPELIEAADLVTEMTLVKHPFKDGVVAQKGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=202, Percent_Identity=40.5940594059406, Blast_Score=159, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23053; Mature: 22922

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDENERHNAKMRKIKAARDKMMEQKTEQKGLIMVHTGKGKGKSSSGFGMIMRCISHKIP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCCC
CAVVQFIKGNWDTGEKSFLRDNYADECRFFVSGEGFTWETQDRARDIAAAENGWRIAKEQ
HHHHHHHHCCCCCCCHHHHHCCCCCCCEEEECCCCCEECCHHHHHHHHHCCCCCHHHHHH
ILDPDIQFVLLDEINIALRYDYLNIDEVVEFLLTQKPHMTHVCLTGRNAKPELIEAADLV
HCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHH
TEMTLVKHPFKDGVVAQKGIEF
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDENERHNAKMRKIKAARDKMMEQKTEQKGLIMVHTGKGKGKSSSGFGMIMRCISHKIP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCCC
CAVVQFIKGNWDTGEKSFLRDNYADECRFFVSGEGFTWETQDRARDIAAAENGWRIAKEQ
HHHHHHHHCCCCCCCHHHHHCCCCCCCEEEECCCCCEECCHHHHHHHHHCCCCCHHHHHH
ILDPDIQFVLLDEINIALRYDYLNIDEVVEFLLTQKPHMTHVCLTGRNAKPELIEAADLV
HCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHH
TEMTLVKHPFKDGVVAQKGIEF
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]