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The map label for this gene is phaC [H]

Identifier: 110679178

GI number: 110679178

Start: 1803607

End: 1805412

Strand: Direct

Name: phaC [H]

Synonym: RD1_1888

Alternate gene names: 110679178

Gene position: 1803607-1805412 (Clockwise)

Preceding gene: 110679176

Following gene: 110679179

Centisome position: 43.64

GC content: 54.98

Gene sequence:

>1806_bases
ATGACAACAAAAAGTGACGGAAGTGTTGTCCCAAGTGGCGAAACACTCGAAAAAATGACCGAAAACCTCAAAAAAGTAGA
GGTGTTGTCAGAACGTTTGCAAAGGGTCATTACGCAACGACAGGGCCACAATCCGGCCCTGGATGGCCCGAATCAAGAAT
TGTTCGGACGCGCGGCACAAGCCTATTGGGCGGAAATGATGAGCAACCCGGCCAAGGTGCTGGAGCATCAGATGTCCTAT
TGGTCCGACACGATGAAGCATTTTGTGCAAGCGCAGCAAGTTCTGGCGCAGGGCAAACTGGCAGCCCCCGAAGACCCGGG
GCCCAAGGACAAACGCTTTGCCAACCCGCTGTGGGACACGCACCCCTATTTCAACTACATCAAGCAGCAGTACCTGATCA
ACGCGCAAGCGCTGCAGACCGCGGTTCAGGATGTGACTGAGTTGGACGAGTTGGAAAAGACACGGCTGAACTATTTTGCC
CAACAGATCGTCGATATGATGTCCCCGACGAATTTTCTGGCGACGAACCCCGATGCCCTTGAGAAAGCGATCGAGACCGA
AGGCCAGAGCCTGGTGCAGGGGCTTGAAAACCTGATCAGCGATCTTGAAGCGAACAATGGCGAAATGGTGGTCAAGCTCG
CGGACGAAAACGCTTTTGAATTGGGCCGCAACATCGCCACAACGCCCGGTAAGGTCGTTTATCGCAATCGGATGATGGAA
TTGGTGCAATATACGCCCAGCACCGAGCAGGTCCACAAGACCCCGCTGGTGATCTTTCCGCCGTGGATCAACAAGTTCTA
CATCCTCGACCTCAAGGCACAGAACAGCCTCGTTAAATGGGCCGTCGAACAGGGGCAGACGGTCTTTATCGTCTCTTGGA
TCAATCCCGACCCGACCTACCGCGATATCGGCATGGAGGACTATATAGAAGACGGGTATCTGGCCGCCATTCGCGAGGTC
AAGGAGATCTGCGGCGAAAATCAGGTCAATGCGGTCGGGTATTGTATTGCCGGCACCACGCTTGCACTCACGCTTTCCTT
GATGAAGCAGCGCGGTGACAAGTCGATCAAGTCGGCCACCTTCTTTACGGCGCTGACGGATTTTTCGGATCAGGGCGAAT
TCACACCGTTTCTGACCAATGACTTCATTGATGGCATCGAGGCGGAGATCGAGGACAAGGGGGTGCTGCCCTCGGTCATC
ATGGCGCGCACATTTTCGTTTTTGCGCTCCAACGATCTGATCTACGGGCCTGCCATCAAGAGCTATATGATGGGGCAATC
GCCGCCTGCATTCGATCTGCTCTATTGGAATGGGGATGGGGCAAACCTGCCGGGTAAAATGGCGATGCAGTACTTGCGGG
GGCTGTGCCAGCGCAATGAGCTGGCGGGGGATGGGTTCGAACTGCTGGGCCACAAGCTGACACTTGCGGATATTGATGTG
CCGCTCTGCGCGGTGGCCTGCGAGACGGATCACATCGCCGCATGGAAAGACAGCTACCGTGGCATTCAGCAGATGGGATC
AAAGGACAAGACCTTCATCATGACCCAGTCCGGGCATATTGCCGGGATCGTCAATCCACCGACCAAAAACAAATACGGGC
ACTACACGAACCCCGATATGAAACTGGACTACAAGGACTGGCAGGCTGGCGCCGACTTCCACGAAGGGTCGTGGTGGCCG
CTTTGGGGCGAATGGCTGAAAAAGCGATCAGGTCGCAAGGTCAAGGCGCGCATTCCAGGTGATTCCACCCATGAAATTCT
CTGTGATGCGCCGGGAACCTATGTTGCGATGAAAGCAACGCTCTGA

Upstream 100 bases:

>100_bases
CCTTAACCATTGCCCGGATTGCCGAGACAGACAGTCGCATCGCCCCCTGAAAGCCAACGACGTAATGCTGCAGGTGCAAA
CATAGGGAGTAAAGGTTCCG

Downstream 100 bases:

>100_bases
ATTTTAATGAAATTCTGCGCTGCGGCATTTATTTGTGCTGCAGTGCAGAAAAAAGCTTGCAATGCTGCGCTGCGGCATCT
ATATATTTCTCAGACGCAAC

Product: poly(3-hydroxyalkanoate) polymerase, putative

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTTKSDGSVVPSGETLEKMTENLKKVEVLSERLQRVITQRQGHNPALDGPNQELFGRAAQAYWAEMMSNPAKVLEHQMSY
WSDTMKHFVQAQQVLAQGKLAAPEDPGPKDKRFANPLWDTHPYFNYIKQQYLINAQALQTAVQDVTELDELEKTRLNYFA
QQIVDMMSPTNFLATNPDALEKAIETEGQSLVQGLENLISDLEANNGEMVVKLADENAFELGRNIATTPGKVVYRNRMME
LVQYTPSTEQVHKTPLVIFPPWINKFYILDLKAQNSLVKWAVEQGQTVFIVSWINPDPTYRDIGMEDYIEDGYLAAIREV
KEICGENQVNAVGYCIAGTTLALTLSLMKQRGDKSIKSATFFTALTDFSDQGEFTPFLTNDFIDGIEAEIEDKGVLPSVI
MARTFSFLRSNDLIYGPAIKSYMMGQSPPAFDLLYWNGDGANLPGKMAMQYLRGLCQRNELAGDGFELLGHKLTLADIDV
PLCAVACETDHIAAWKDSYRGIQQMGSKDKTFIMTQSGHIAGIVNPPTKNKYGHYTNPDMKLDYKDWQAGADFHEGSWWP
LWGEWLKKRSGRKVKARIPGDSTHEILCDAPGTYVAMKATL

Sequences:

>Translated_601_residues
MTTKSDGSVVPSGETLEKMTENLKKVEVLSERLQRVITQRQGHNPALDGPNQELFGRAAQAYWAEMMSNPAKVLEHQMSY
WSDTMKHFVQAQQVLAQGKLAAPEDPGPKDKRFANPLWDTHPYFNYIKQQYLINAQALQTAVQDVTELDELEKTRLNYFA
QQIVDMMSPTNFLATNPDALEKAIETEGQSLVQGLENLISDLEANNGEMVVKLADENAFELGRNIATTPGKVVYRNRMME
LVQYTPSTEQVHKTPLVIFPPWINKFYILDLKAQNSLVKWAVEQGQTVFIVSWINPDPTYRDIGMEDYIEDGYLAAIREV
KEICGENQVNAVGYCIAGTTLALTLSLMKQRGDKSIKSATFFTALTDFSDQGEFTPFLTNDFIDGIEAEIEDKGVLPSVI
MARTFSFLRSNDLIYGPAIKSYMMGQSPPAFDLLYWNGDGANLPGKMAMQYLRGLCQRNELAGDGFELLGHKLTLADIDV
PLCAVACETDHIAAWKDSYRGIQQMGSKDKTFIMTQSGHIAGIVNPPTKNKYGHYTNPDMKLDYKDWQAGADFHEGSWWP
LWGEWLKKRSGRKVKARIPGDSTHEILCDAPGTYVAMKATL
>Mature_600_residues
TTKSDGSVVPSGETLEKMTENLKKVEVLSERLQRVITQRQGHNPALDGPNQELFGRAAQAYWAEMMSNPAKVLEHQMSYW
SDTMKHFVQAQQVLAQGKLAAPEDPGPKDKRFANPLWDTHPYFNYIKQQYLINAQALQTAVQDVTELDELEKTRLNYFAQ
QIVDMMSPTNFLATNPDALEKAIETEGQSLVQGLENLISDLEANNGEMVVKLADENAFELGRNIATTPGKVVYRNRMMEL
VQYTPSTEQVHKTPLVIFPPWINKFYILDLKAQNSLVKWAVEQGQTVFIVSWINPDPTYRDIGMEDYIEDGYLAAIREVK
EICGENQVNAVGYCIAGTTLALTLSLMKQRGDKSIKSATFFTALTDFSDQGEFTPFLTNDFIDGIEAEIEDKGVLPSVIM
ARTFSFLRSNDLIYGPAIKSYMMGQSPPAFDLLYWNGDGANLPGKMAMQYLRGLCQRNELAGDGFELLGHKLTLADIDVP
LCAVACETDHIAAWKDSYRGIQQMGSKDKTFIMTQSGHIAGIVNPPTKNKYGHYTNPDMKLDYKDWQAGADFHEGSWWPL
WGEWLKKRSGRKVKARIPGDSTHEILCDAPGTYVAMKATL

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 67464; Mature: 67333

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKSDGSVVPSGETLEKMTENLKKVEVLSERLQRVITQRQGHNPALDGPNQELFGRAAQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AYWAEMMSNPAKVLEHQMSYWSDTMKHFVQAQQVLAQGKLAAPEDPGPKDKRFANPLWDT
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCC
HPYFNYIKQQYLINAQALQTAVQDVTELDELEKTRLNYFAQQIVDMMSPTNFLATNPDAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
EKAIETEGQSLVQGLENLISDLEANNGEMVVKLADENAFELGRNIATTPGKVVYRNRMME
HHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHH
LVQYTPSTEQVHKTPLVIFPPWINKFYILDLKAQNSLVKWAVEQGQTVFIVSWINPDPTY
HHHCCCCHHHHHCCCEEEECCCCCEEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCCC
RDIGMEDYIEDGYLAAIREVKEICGENQVNAVGYCIAGTTLALTLSLMKQRGDKSIKSAT
HHCCHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHH
FFTALTDFSDQGEFTPFLTNDFIDGIEAEIEDKGVLPSVIMARTFSFLRSNDLIYGPAIK
HHHHHHCCCCCCCCCCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHH
SYMMGQSPPAFDLLYWNGDGANLPGKMAMQYLRGLCQRNELAGDGFELLGHKLTLADIDV
HHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEECCC
PLCAVACETDHIAAWKDSYRGIQQMGSKDKTFIMTQSGHIAGIVNPPTKNKYGHYTNPDM
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCC
KLDYKDWQAGADFHEGSWWPLWGEWLKKRSGRKVKARIPGDSTHEILCDAPGTYVAMKAT
EECCHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEEEEEC
L
C
>Mature Secondary Structure 
TTKSDGSVVPSGETLEKMTENLKKVEVLSERLQRVITQRQGHNPALDGPNQELFGRAAQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AYWAEMMSNPAKVLEHQMSYWSDTMKHFVQAQQVLAQGKLAAPEDPGPKDKRFANPLWDT
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCC
HPYFNYIKQQYLINAQALQTAVQDVTELDELEKTRLNYFAQQIVDMMSPTNFLATNPDAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
EKAIETEGQSLVQGLENLISDLEANNGEMVVKLADENAFELGRNIATTPGKVVYRNRMME
HHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHH
LVQYTPSTEQVHKTPLVIFPPWINKFYILDLKAQNSLVKWAVEQGQTVFIVSWINPDPTY
HHHCCCCHHHHHCCCEEEECCCCCEEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCCC
RDIGMEDYIEDGYLAAIREVKEICGENQVNAVGYCIAGTTLALTLSLMKQRGDKSIKSAT
HHCCHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHH
FFTALTDFSDQGEFTPFLTNDFIDGIEAEIEDKGVLPSVIMARTFSFLRSNDLIYGPAIK
HHHHHHCCCCCCCCCCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHH
SYMMGQSPPAFDLLYWNGDGANLPGKMAMQYLRGLCQRNELAGDGFELLGHKLTLADIDV
HHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEECCC
PLCAVACETDHIAAWKDSYRGIQQMGSKDKTFIMTQSGHIAGIVNPPTKNKYGHYTNPDM
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCC
KLDYKDWQAGADFHEGSWWPLWGEWLKKRSGRKVKARIPGDSTHEILCDAPGTYVAMKAT
EECCHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEEEEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748438 [H]