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The map label for this gene is bioH [H]

Identifier: 110679176

GI number: 110679176

Start: 1801487

End: 1802200

Strand: Direct

Name: bioH [H]

Synonym: RD1_1886

Alternate gene names: 110679176

Gene position: 1801487-1802200 (Clockwise)

Preceding gene: 110679175

Following gene: 110679178

Centisome position: 43.59

GC content: 62.89

Gene sequence:

>714_bases
ATGGTGGCTGAACCGCTCGTTCTGTTGCCCGGTATGATGTGCGATGCGCGGCTGTTCGGCCCCCAGATCGCCGAGCTTTC
CATTGATACGGCGGTGATGGTTGCGCCGATTACACGCGGCGAGCGTGTCGAGGAAATCGCATCGGGTCTGTTGGATGAAT
TGCCCCAACGCTTTGCTCTTGCTGGGCTGAGCATGGGGGGCATCGTCGCGATGGAACTCCTGCGACGCGCGCCGGAGCGG
GTGACGCGTATCGCGCTGATGGACACCAATCCGCTGGCAGAGACGCCACAGGTGGCCGCCGGGCGGGAACCGCAGATTGT
CGCGGCGCGCACCGGTCGAATGCTGGATGTGATGCGCGAAGAAATGAAGCCCAATTACCTTGCCCCCGGCCCGGCACGGG
TCGAGGTTCTGGATCTGGTCATGGATATGGCCGCCGCCGCCGGGCCGGAAGTTTTCGTGCGTCAGTCGCGCGCCCTTCAG
CGCCGCCCGGACCAGCAGACGACGCTGCGCAAATGCAAAGTGCCTGCACTGGTTCTTTGCGGGGCGCATGACGCGCTTTG
CCCGGTGAAGCGACATGAATTCATGGCGGAACTGATCCCGTCAGCCGTGTTGCGTGTGTTGGACAATGCTGGTCATTTGC
CTACCCTCGAGCATCCCGCGCAAACGACGCAGGCGCTCAGGGAATGGATGTCACAGCCTTACGTCGTGACCTGA

Upstream 100 bases:

>100_bases
TGTGATTTTGGCCCATGCGAGTCACAACTGCGCAAACACTGCTTTCCAGGTTCGAACACCGTGATGAACACACATCACCC
TTCCAAAATACAGGGCCGGC

Downstream 100 bases:

>100_bases
CACGGGGCCGTCAGGCCGCCGCGTTCTTGTTTGCAGCCTTTTTGGTTTTCGGCTCCGGCTGGTCGTCGCCACTGTTGGCG
TCGATGAAGTCCAGAACCAA

Product: hydrolase, putative

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVAEPLVLLPGMMCDARLFGPQIAELSIDTAVMVAPITRGERVEEIASGLLDELPQRFALAGLSMGGIVAMELLRRAPER
VTRIALMDTNPLAETPQVAAGREPQIVAARTGRMLDVMREEMKPNYLAPGPARVEVLDLVMDMAAAAGPEVFVRQSRALQ
RRPDQQTTLRKCKVPALVLCGAHDALCPVKRHEFMAELIPSAVLRVLDNAGHLPTLEHPAQTTQALREWMSQPYVVT

Sequences:

>Translated_237_residues
MVAEPLVLLPGMMCDARLFGPQIAELSIDTAVMVAPITRGERVEEIASGLLDELPQRFALAGLSMGGIVAMELLRRAPER
VTRIALMDTNPLAETPQVAAGREPQIVAARTGRMLDVMREEMKPNYLAPGPARVEVLDLVMDMAAAAGPEVFVRQSRALQ
RRPDQQTTLRKCKVPALVLCGAHDALCPVKRHEFMAELIPSAVLRVLDNAGHLPTLEHPAQTTQALREWMSQPYVVT
>Mature_237_residues
MVAEPLVLLPGMMCDARLFGPQIAELSIDTAVMVAPITRGERVEEIASGLLDELPQRFALAGLSMGGIVAMELLRRAPER
VTRIALMDTNPLAETPQVAAGREPQIVAARTGRMLDVMREEMKPNYLAPGPARVEVLDLVMDMAAAAGPEVFVRQSRALQ
RRPDQQTTLRKCKVPALVLCGAHDALCPVKRHEFMAELIPSAVLRVLDNAGHLPTLEHPAQTTQALREWMSQPYVVT

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 25928; Mature: 25928

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAEPLVLLPGMMCDARLFGPQIAELSIDTAVMVAPITRGERVEEIASGLLDELPQRFAL
CCCCCHHHHCCCHHHHHHCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AGLSMGGIVAMELLRRAPERVTRIALMDTNPLAETPQVAAGREPQIVAARTGRMLDVMRE
HCCCCHHHHHHHHHHHHHHHHHEEHEECCCCCCCCCCCCCCCCCCEEHHHCCHHHHHHHH
EMKPNYLAPGPARVEVLDLVMDMAAAAGPEVFVRQSRALQRRPDQQTTLRKCKVPALVLC
HCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEE
GAHDALCPVKRHEFMAELIPSAVLRVLDNAGHLPTLEHPAQTTQALREWMSQPYVVT
CCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MVAEPLVLLPGMMCDARLFGPQIAELSIDTAVMVAPITRGERVEEIASGLLDELPQRFAL
CCCCCHHHHCCCHHHHHHCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AGLSMGGIVAMELLRRAPERVTRIALMDTNPLAETPQVAAGREPQIVAARTGRMLDVMRE
HCCCCHHHHHHHHHHHHHHHHHEEHEECCCCCCCCCCCCCCCCCCEEHHHCCHHHHHHHH
EMKPNYLAPGPARVEVLDLVMDMAAAAGPEVFVRQSRALQRRPDQQTTLRKCKVPALVLC
HCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEE
GAHDALCPVKRHEFMAELIPSAVLRVLDNAGHLPTLEHPAQTTQALREWMSQPYVVT
CCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA