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The map label for this gene is rutD [H]

Identifier: 110679136

GI number: 110679136

Start: 1767846

End: 1768589

Strand: Direct

Name: rutD [H]

Synonym: RD1_1842

Alternate gene names: 110679136

Gene position: 1767846-1768589 (Clockwise)

Preceding gene: 110679135

Following gene: 110679137

Centisome position: 42.77

GC content: 61.02

Gene sequence:

>744_bases
GTGACACCTCTGGTGATGGTGCATGGTTTCATGGGCGGCAGCGCACAATGGGCCGGAGAGGTCGCGCGGCTCTCGGACAT
ACGCGAGGTGATTGCACTCGATCTGCCAGGGTTCGGGGCAAACAGCCATCTCGCCCCGGTCAACACCATTTGCGGGTTTG
CGGATTGGGTGATTGACACGTTGGACCGCAGGGGGGTGCAGGATTTTGATCTGTTGGGGCATTCGATGGGCGGGATGATC
GTGCAGGAGATGGCGCGCAAGTCCCCGGACAGGATCGGGAAACTCGTGCTCTATGCCACGGGAGCCAAAGGTGTTTTGCC
CGGACGCTTTGAGCCCATCGCTGAAAGCCAGGAGCGCGCCCGGCTGGACGGTGCACAGGCCACCGCCAGACGCATTGCCG
CAACGTGGTTCCTGCACCGCGAGGCGGCACCGGCCTATGAAGACTGTGCAGCGATTGCAGAACACGCAAGTCTGGGCGCG
ATATTGGCAGGCCTCGATGCCATGCAAGGCTGGTCAGGAGAAACAGCGCTTGGCGATTTGACCCGGGAAACGCTGATCAT
CTGGGGGGATTGCGACCGCACCTATGCGTGGGAGCAGACCGCCTTGCTATGGCAGGCGATTGAGAAGGCGCACCTCGCTG
TTGTTCCGGGATGCGCCCATGCGGTACACCTTGAAAAACCGGAACTCTTTGCCGCTTTGTTGCGCGACTACTTGCAGCCT
CCCGAGCCCAAGGCGATAATTTGA

Upstream 100 bases:

>100_bases
AGGCCTTGCAATACGCCAATGTGGGGCAGGGGATTCTGGCGGGCTTTGCGATCCTGTTCTGTGCCATGATCCTTGACCGA
ATTGTGCAGGGCAAGCGCAA

Downstream 100 bases:

>100_bases
TAGGTGGGTGCGGTCGTTTTCCTTGCGGCGGAACCTGTCGACATCGTGAGAAAACGATCCGTCTTGATGTGCGCGGCGCC
GGAAGCCTTTTACCTCATAC

Product: hydrolase, putative

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTPLVMVHGFMGGSAQWAGEVARLSDIREVIALDLPGFGANSHLAPVNTICGFADWVIDTLDRRGVQDFDLLGHSMGGMI
VQEMARKSPDRIGKLVLYATGAKGVLPGRFEPIAESQERARLDGAQATARRIAATWFLHREAAPAYEDCAAIAEHASLGA
ILAGLDAMQGWSGETALGDLTRETLIIWGDCDRTYAWEQTALLWQAIEKAHLAVVPGCAHAVHLEKPELFAALLRDYLQP
PEPKAII

Sequences:

>Translated_247_residues
MTPLVMVHGFMGGSAQWAGEVARLSDIREVIALDLPGFGANSHLAPVNTICGFADWVIDTLDRRGVQDFDLLGHSMGGMI
VQEMARKSPDRIGKLVLYATGAKGVLPGRFEPIAESQERARLDGAQATARRIAATWFLHREAAPAYEDCAAIAEHASLGA
ILAGLDAMQGWSGETALGDLTRETLIIWGDCDRTYAWEQTALLWQAIEKAHLAVVPGCAHAVHLEKPELFAALLRDYLQP
PEPKAII
>Mature_246_residues
TPLVMVHGFMGGSAQWAGEVARLSDIREVIALDLPGFGANSHLAPVNTICGFADWVIDTLDRRGVQDFDLLGHSMGGMIV
QEMARKSPDRIGKLVLYATGAKGVLPGRFEPIAESQERARLDGAQATARRIAATWFLHREAAPAYEDCAAIAEHASLGAI
LAGLDAMQGWSGETALGDLTRETLIIWGDCDRTYAWEQTALLWQAIEKAHLAVVPGCAHAVHLEKPELFAALLRDYLQPP
EPKAII

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Caenorhabditis elegans, GI32566936, Length=99, Percent_Identity=34.3434343434343, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146278, Length=125, Percent_Identity=32, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558492, Length=99, Percent_Identity=34.3434343434343, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 26747; Mature: 26616

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLVMVHGFMGGSAQWAGEVARLSDIREVIALDLPGFGANSHLAPVNTICGFADWVIDT
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
LDRRGVQDFDLLGHSMGGMIVQEMARKSPDRIGKLVLYATGAKGVLPGRFEPIAESQERA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHH
RLDGAQATARRIAATWFLHREAAPAYEDCAAIAEHASLGAILAGLDAMQGWSGETALGDL
HHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
TRETLIIWGDCDRTYAWEQTALLWQAIEKAHLAVVPGCAHAVHLEKPELFAALLRDYLQP
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCHHEEECCCHHHHHHHHHHHCCC
PEPKAII
CCCCCCC
>Mature Secondary Structure 
TPLVMVHGFMGGSAQWAGEVARLSDIREVIALDLPGFGANSHLAPVNTICGFADWVIDT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
LDRRGVQDFDLLGHSMGGMIVQEMARKSPDRIGKLVLYATGAKGVLPGRFEPIAESQERA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHH
RLDGAQATARRIAATWFLHREAAPAYEDCAAIAEHASLGAILAGLDAMQGWSGETALGDL
HHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
TRETLIIWGDCDRTYAWEQTALLWQAIEKAHLAVVPGCAHAVHLEKPELFAALLRDYLQP
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCHHEEECCCHHHHHHHHHHHCCC
PEPKAII
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA