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The map label for this gene is ribH [H]

Identifier: 110679099

GI number: 110679099

Start: 1731722

End: 1732273

Strand: Direct

Name: ribH [H]

Synonym: RD1_1803

Alternate gene names: 110679099

Gene position: 1731722-1732273 (Clockwise)

Preceding gene: 110679098

Following gene: 110679100

Centisome position: 41.9

GC content: 61.78

Gene sequence:

>552_bases
ATGGCCGCACATGAACAGCACCACGTCTTGCCGCGTCCGACATTCGAAAAGCCGGTGAAGATTCTGATCGTGGTCGCTCC
CTATTACAAGGACATCGCCGAAAGTCTGGTGGCAGGTGCCCAAGGCGAGATTGAAGCGGCGGGCGGCACGTGGGAAGTGG
CGGAAATGCCCGGCGCGCTTGAGGTGCCCACGGCGATTGCCATGGCGGACCGGCGCAGCAATTTTGACGGCTATGTGGCC
TTGGGCTGCGTGATCCGTGGCGAAACGACCCATTATGAGACGGTCTGCAATGACAGCAGCCGTGCCTTGCAGCTTTTGGG
GCTACAGGGGCTTTGCATCGGCAATGGCATCCTGACTGTCGAGACGCGCGCGCAGGCCGAGGCACGCGCAGAGGTTTCGG
GTCAGAACAAGGGCGGCGGTGCGGCGGCTGCGGCGTTGCATCTGATCGCACTGGCGCGTAAGTGGTCCTCCGAGAGCAAG
GGCATCGGCTTCAAGCCGCTGGGTCAAACGATCCGGATGGCTGGCGATACGGACGGAACTAACACAGTATGA

Upstream 100 bases:

>100_bases
ACTGATCCTGCTGACCGACAGCCCGCAAACGAAATACCTGGGGCTTGAAGCCTACAACCTCTCCATCGTCGGGACCCGCC
CGATTACAAAGGACTGAACC

Downstream 100 bases:

>100_bases
GCGCGTTTCACGGGAACCTGTCGGGCAATCAGCGCCGCAAGATGAAATCTGCCGCGCGGCTTTATGCGGTGCAGGCGCTG
TTTCAGATGGAGCATTCGGG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MAAHEQHHVLPRPTFEKPVKILIVVAPYYKDIAESLVAGAQGEIEAAGGTWEVAEMPGALEVPTAIAMADRRSNFDGYVA
LGCVIRGETTHYETVCNDSSRALQLLGLQGLCIGNGILTVETRAQAEARAEVSGQNKGGGAAAAALHLIALARKWSSESK
GIGFKPLGQTIRMAGDTDGTNTV

Sequences:

>Translated_183_residues
MAAHEQHHVLPRPTFEKPVKILIVVAPYYKDIAESLVAGAQGEIEAAGGTWEVAEMPGALEVPTAIAMADRRSNFDGYVA
LGCVIRGETTHYETVCNDSSRALQLLGLQGLCIGNGILTVETRAQAEARAEVSGQNKGGGAAAAALHLIALARKWSSESK
GIGFKPLGQTIRMAGDTDGTNTV
>Mature_182_residues
AAHEQHHVLPRPTFEKPVKILIVVAPYYKDIAESLVAGAQGEIEAAGGTWEVAEMPGALEVPTAIAMADRRSNFDGYVAL
GCVIRGETTHYETVCNDSSRALQLLGLQGLCIGNGILTVETRAQAEARAEVSGQNKGGGAAAAALHLIALARKWSSESKG
IGFKPLGQTIRMAGDTDGTNTV

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=135, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 19211; Mature: 19080

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHEQHHVLPRPTFEKPVKILIVVAPYYKDIAESLVAGAQGEIEAAGGTWEVAEMPGAL
CCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEECCCEEEHHHCCCCC
EVPTAIAMADRRSNFDGYVALGCVIRGETTHYETVCNDSSRALQLLGLQGLCIGNGILTV
CCCHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHCCCHHHHHHHCCCCEEECCCEEEE
ETRAQAEARAEVSGQNKGGGAAAAALHLIALARKWSSESKGIGFKPLGQTIRMAGDTDGT
ECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCC
NTV
CCC
>Mature Secondary Structure 
AAHEQHHVLPRPTFEKPVKILIVVAPYYKDIAESLVAGAQGEIEAAGGTWEVAEMPGAL
CCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEECCCEEEHHHCCCCC
EVPTAIAMADRRSNFDGYVALGCVIRGETTHYETVCNDSSRALQLLGLQGLCIGNGILTV
CCCHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHCCCHHHHHHHCCCCEEECCCEEEE
ETRAQAEARAEVSGQNKGGGAAAAALHLIALARKWSSESKGIGFKPLGQTIRMAGDTDGT
ECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCC
NTV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA