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The map label for this gene is ribE [H]

Identifier: 110679097

GI number: 110679097

Start: 1729930

End: 1730523

Strand: Direct

Name: ribE [H]

Synonym: RD1_1800

Alternate gene names: 110679097

Gene position: 1729930-1730523 (Clockwise)

Preceding gene: 110679096

Following gene: 110679098

Centisome position: 41.86

GC content: 62.46

Gene sequence:

>594_bases
ATGTTTACGGGAATCATTACCGACATCGGCACGATCATCGACCTCAAGCAGGAGGGCGACCTGCGGGCGCGCATTCGCAC
GGGTTATGATACGTCCGGCATTGATATGGGGGCCTCCATCGCGTCGGATGGTGTCTGCCTGACCGTGGTCGATCTCGGGC
CGGATTGGTATGATGTGCAGATCAGCGCCGAGACCGTGAGCAAGACGAACCTCACCCAGTGGGCCGTCGGCGGTCGCGTC
AACCTCGAACGCGCGTTGCGTGTGGGCGATGAGTTGGGCGGCCATATCGTGTCCGGGCATGTGGACGGTGTCGCCGAGGT
CATCGCGGTCACGGAGGAGGGCGACAGCACGCGGGTGACACTGCGCGCCCCTGAGGCACTGGCACGGTTCATCGCGCCCA
AAGGGTCGGTGGCCCTCAACGGGACCTCTCTGACGGTGAACGAGGTCGACGGCAGGGACTTCGGGATCAACTTCATTCCC
CATACGAAAGAAGTCACAACATGGGGCGGTGTGCGCGTTGGGGATGCGGTGAACCTTGAGATTGACACGCTGGCCCGTTA
CGTCGCGCGTCTTGCGGAAATGCCTGCGCATTGA

Upstream 100 bases:

>100_bases
TGCACGAATGCCAGCCGCAAGGCCGTGACGCGCTGCGGGGGCTTGTCAGCTTTGGGTCGCGCCGCTACGTCATCACAAAC
ACCAGCACGGCGGGGCTTTC

Downstream 100 bases:

>100_bases
ACCGGGGGCGGCTGGTCAAGCCTTGCCGCTTGGTCTATGAGCCTGTCCCAGACAAAGAGGCGTGCATGCTATGACATTTG
AAACATCCGGCCCAGTTGAG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MFTGIITDIGTIIDLKQEGDLRARIRTGYDTSGIDMGASIASDGVCLTVVDLGPDWYDVQISAETVSKTNLTQWAVGGRV
NLERALRVGDELGGHIVSGHVDGVAEVIAVTEEGDSTRVTLRAPEALARFIAPKGSVALNGTSLTVNEVDGRDFGINFIP
HTKEVTTWGGVRVGDAVNLEIDTLARYVARLAEMPAH

Sequences:

>Translated_197_residues
MFTGIITDIGTIIDLKQEGDLRARIRTGYDTSGIDMGASIASDGVCLTVVDLGPDWYDVQISAETVSKTNLTQWAVGGRV
NLERALRVGDELGGHIVSGHVDGVAEVIAVTEEGDSTRVTLRAPEALARFIAPKGSVALNGTSLTVNEVDGRDFGINFIP
HTKEVTTWGGVRVGDAVNLEIDTLARYVARLAEMPAH
>Mature_197_residues
MFTGIITDIGTIIDLKQEGDLRARIRTGYDTSGIDMGASIASDGVCLTVVDLGPDWYDVQISAETVSKTNLTQWAVGGRV
NLERALRVGDELGGHIVSGHVDGVAEVIAVTEEGDSTRVTLRAPEALARFIAPKGSVALNGTSLTVNEVDGRDFGINFIP
HTKEVTTWGGVRVGDAVNLEIDTLARYVARLAEMPAH

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=196, Percent_Identity=34.1836734693878, Blast_Score=117, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319733, Length=204, Percent_Identity=36.7647058823529, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 20960; Mature: 20960

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIITDIGTIIDLKQEGDLRARIRTGYDTSGIDMGASIASDGVCLTVVDLGPDWYDVQ
CCCCHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
ISAETVSKTNLTQWAVGGRVNLERALRVGDELGGHIVSGHVDGVAEVIAVTEEGDSTRVT
EEHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEEEECCCCEEEE
LRAPEALARFIAPKGSVALNGTSLTVNEVDGRDFGINFIPHTKEVTTWGGVRVGDAVNLE
EECHHHHHHHHCCCCCEEECCCEEEEEECCCCEECEEECCCCCEEECCCCEEECCEEEEE
IDTLARYVARLAEMPAH
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIITDIGTIIDLKQEGDLRARIRTGYDTSGIDMGASIASDGVCLTVVDLGPDWYDVQ
CCCCHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
ISAETVSKTNLTQWAVGGRVNLERALRVGDELGGHIVSGHVDGVAEVIAVTEEGDSTRVT
EEHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEEEECCCCEEEE
LRAPEALARFIAPKGSVALNGTSLTVNEVDGRDFGINFIPHTKEVTTWGGVRVGDAVNLE
EECHHHHHHHHCCCCCEEECCCEEEEEECCCCEECEEECCCCCEEECCCCEEECCEEEEE
IDTLARYVARLAEMPAH
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]