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The map label for this gene is nagA [H]

Identifier: 110679026

GI number: 110679026

Start: 1655919

End: 1657049

Strand: Reverse

Name: nagA [H]

Synonym: RD1_1725

Alternate gene names: 110679026

Gene position: 1657049-1655919 (Counterclockwise)

Preceding gene: 110679027

Following gene: 110679019

Centisome position: 40.09

GC content: 63.04

Gene sequence:

>1131_bases
GTGATGAAACGCGCATATACGGGAGCGGATATCTTTGATGGCAGCACGCTCAGCTCTGACAGCGCGCTGCTGTTGGATGG
CGGTGTCTATCGCGGTGTCGTGCCAAGGCGTGACATCCCGTCTGACTACGCGGTTGAAACCTTGCCGGGGGGTACGATCC
TGCCGGGGTTTGTTGATTTGCAGGTCAACGGTGGTGGCGGTGTTCTGTTTAACGAGGATCCTTCAGTGGCAGGTTTGCAT
GCCATCGCGCAGGCGCATGCGACCACGGGAACGCGCGCCCTGCTGCCCACGCTCATCACCGACACGCCAGCGCGCACACA
GGCAGCCGTCGACGCCGTCGCGGCGGCCATTGAACGCAAGGTGGCGGGGATCATCGGCATTCACCTTGAGGGGCCGCACC
TGAGCCTTGCCAAAAAGGGGGCGCATGACCCCGCCTTGATCCGCCCGATGACGGATGCGGATGAAGCATTTTTGCACGAT
GCTGCACGGCGTTTGCCAAACATCATGCTCACGGTGGCCCCGGAAAATGTGACGAACGCACAGATCACCCGCCTGTCCCG
CGCTGGTATCATCATTTCGCTGGGTCACACCGATTGCAGCATGGCCGATGCGCAAGCCGCCTTTCGGGCCGGTGCCCGCT
GCGTCACGCATCTGTTCAACGCGATGCGCCAGCTGGGCAGTCGTGAACCGGGCCTTGTCGGGGCGGCGCTGGATACCGGT
GATGTGCATGCAGGTCTGATCGCGGATGATATCCACGTGCACCGGGCCAGCATGCGCGCAGCTCTTTGCGCCAAGCGCGC
GGGTGGCGGTATTTTTCTGGTGACCGACGCCATGGCCACCGCCGGGTCCGACATCACGGAATTCCGTCTCAACGGGCGGC
GCGTGCTGCGTCGGAACGGTCGCCTGACCCTGGAGGATGGCACGCTTGCCGGGGCTGATCTGACGTTTCCGCGTGCGCTG
GACGTTCTGATCAACATCGTGGGCTGCGAAAAAGAGGTCGCGTTTTCGATGGCAACCCGTGGCCCTGCGTGTGTCTTGAC
CAACCCTGGCGCGGTGGGGCGGTTTACACTGGACCACGGCGCGCAGGCCATCCATCTGGACGATGATCTGCGCTATGTCG
GGGGTCTGTAG

Upstream 100 bases:

>100_bases
CGTTGATCGTTTCATTCTACGCCATGGTCGAACAGGTCGCCCGGGCGCGCGGCATCAACCCCGATGCGCCGCGCCACCTC
AGGAAAGTGACGGAAACACT

Downstream 100 bases:

>100_bases
GGGCGCTGTCTGATATCCCGAAAGACGCTATAGCGCCGATCGCATCCGTTACCGACGCCGCAAGCCCTGCCATGCACGCA
GCCGCAGCACCACATAGCCC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MMKRAYTGADIFDGSTLSSDSALLLDGGVYRGVVPRRDIPSDYAVETLPGGTILPGFVDLQVNGGGGVLFNEDPSVAGLH
AIAQAHATTGTRALLPTLITDTPARTQAAVDAVAAAIERKVAGIIGIHLEGPHLSLAKKGAHDPALIRPMTDADEAFLHD
AARRLPNIMLTVAPENVTNAQITRLSRAGIIISLGHTDCSMADAQAAFRAGARCVTHLFNAMRQLGSREPGLVGAALDTG
DVHAGLIADDIHVHRASMRAALCAKRAGGGIFLVTDAMATAGSDITEFRLNGRRVLRRNGRLTLEDGTLAGADLTFPRAL
DVLINIVGCEKEVAFSMATRGPACVLTNPGAVGRFTLDHGAQAIHLDDDLRYVGGL

Sequences:

>Translated_376_residues
MMKRAYTGADIFDGSTLSSDSALLLDGGVYRGVVPRRDIPSDYAVETLPGGTILPGFVDLQVNGGGGVLFNEDPSVAGLH
AIAQAHATTGTRALLPTLITDTPARTQAAVDAVAAAIERKVAGIIGIHLEGPHLSLAKKGAHDPALIRPMTDADEAFLHD
AARRLPNIMLTVAPENVTNAQITRLSRAGIIISLGHTDCSMADAQAAFRAGARCVTHLFNAMRQLGSREPGLVGAALDTG
DVHAGLIADDIHVHRASMRAALCAKRAGGGIFLVTDAMATAGSDITEFRLNGRRVLRRNGRLTLEDGTLAGADLTFPRAL
DVLINIVGCEKEVAFSMATRGPACVLTNPGAVGRFTLDHGAQAIHLDDDLRYVGGL
>Mature_376_residues
MMKRAYTGADIFDGSTLSSDSALLLDGGVYRGVVPRRDIPSDYAVETLPGGTILPGFVDLQVNGGGGVLFNEDPSVAGLH
AIAQAHATTGTRALLPTLITDTPARTQAAVDAVAAAIERKVAGIIGIHLEGPHLSLAKKGAHDPALIRPMTDADEAFLHD
AARRLPNIMLTVAPENVTNAQITRLSRAGIIISLGHTDCSMADAQAAFRAGARCVTHLFNAMRQLGSREPGLVGAALDTG
DVHAGLIADDIHVHRASMRAALCAKRAGGGIFLVTDAMATAGSDITEFRLNGRRVLRRNGRLTLEDGTLAGADLTFPRAL
DVLINIVGCEKEVAFSMATRGPACVLTNPGAVGRFTLDHGAQAIHLDDDLRYVGGL

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI224922791, Length=261, Percent_Identity=36.3984674329502, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI21361513, Length=247, Percent_Identity=36.8421052631579, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1786892, Length=342, Percent_Identity=37.719298245614, Blast_Score=221, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17553768, Length=314, Percent_Identity=32.1656050955414, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI19920392, Length=334, Percent_Identity=33.2335329341317, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281361140, Length=350, Percent_Identity=31.7142857142857, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39293; Mature: 39293

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRAYTGADIFDGSTLSSDSALLLDGGVYRGVVPRRDIPSDYAVETLPGGTILPGFVDL
CCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCCCEEECCCCEECCCEEEE
QVNGGGGVLFNEDPSVAGLHAIAQAHATTGTRALLPTLITDTPARTQAAVDAVAAAIERK
EEECCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VAGIIGIHLEGPHLSLAKKGAHDPALIRPMTDADEAFLHDAARRLPNIMLTVAPENVTNA
HCEEEEEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCH
QITRLSRAGIIISLGHTDCSMADAQAAFRAGARCVTHLFNAMRQLGSREPGLVGAALDTG
HHHEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
DVHAGLIADDIHVHRASMRAALCAKRAGGGIFLVTDAMATAGSDITEFRLNGRRVLRRNG
CCCCCEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCEEEECCCHHHHHCCC
RLTLEDGTLAGADLTFPRALDVLINIVGCEKEVAFSMATRGPACVLTNPGAVGRFTLDHG
CEEEECCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCEEEEECCC
AQAIHLDDDLRYVGGL
CEEEEECCCCHHHCCC
>Mature Secondary Structure
MMKRAYTGADIFDGSTLSSDSALLLDGGVYRGVVPRRDIPSDYAVETLPGGTILPGFVDL
CCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCCCEEECCCCEECCCEEEE
QVNGGGGVLFNEDPSVAGLHAIAQAHATTGTRALLPTLITDTPARTQAAVDAVAAAIERK
EEECCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VAGIIGIHLEGPHLSLAKKGAHDPALIRPMTDADEAFLHDAARRLPNIMLTVAPENVTNA
HCEEEEEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCH
QITRLSRAGIIISLGHTDCSMADAQAAFRAGARCVTHLFNAMRQLGSREPGLVGAALDTG
HHHEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
DVHAGLIADDIHVHRASMRAALCAKRAGGGIFLVTDAMATAGSDITEFRLNGRRVLRRNG
CCCCCEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCEEEECCCHHHHHCCC
RLTLEDGTLAGADLTFPRALDVLINIVGCEKEVAFSMATRGPACVLTNPGAVGRFTLDHG
CEEEECCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCEEEEECCC
AQAIHLDDDLRYVGGL
CEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]