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The map label for this gene is glmS [H]

Identifier: 110679027

GI number: 110679027

Start: 1657046

End: 1658074

Strand: Reverse

Name: glmS [H]

Synonym: RD1_1726

Alternate gene names: 110679027

Gene position: 1658074-1657046 (Counterclockwise)

Preceding gene: 110679028

Following gene: 110679026

Centisome position: 40.12

GC content: 62.1

Gene sequence:

>1029_bases
ATGACTTCTCAAACCCACATGCGGCGCGAAATCCTTGAAATTCCGGACGCGGTCGCAACCCTGCTGACACGGGGCGCGCC
CGAAGTCAGGGCCGCTGCACGCGCCTTGCAAGACGCAGACCCCGCGTTCCTGATTTCGGTTGCGCGCGGCTCGTCCGATC
ACGCAGCGACCTATTTCAAATATGCCACCGAGCTTGTCGCCGGTATTCCGGTTGCCTCCGTCGGCCCGTCAGTTACCTCT
ATCTACGGGCGCAACCTGCGGCTGTCCCGCGGTGCCTGTCTGGCGATTTCGCAGTCAGGGAAAAGCCCGGATATCGTGCG
CATGGCAGAAATGGCCACCGCGCAGGGTGCCGTTTCCATCGCCCTGACCAACCACATCAACAGCGATCTGGCCGGGGTCA
GCACCCATGCGGTCAATCTGCATGCCGGTGTCGAACACAGCGTGGCCGCCACCAAGACATTCGTGACCTCTGCCGTGTCG
GCCATCTGGCTGATGGCCGAGTGGCAGCAGGACCATGCGCTGTTGCGTGCCCTGCATGATTTACCGCAGGTGTTGAAGAA
GGCGGCGCACATGGATTGGTCCATCCTGGAAGATGAGATCGTTTCGTCCCGGTCGCTCTTTTGCCTTGGCCGTGGGCCCG
CGTTGGCGATAGCCAATGAGGCGGCTCTGAAGTTCAAGGAAACCTGCCAACTGCACGCAGAATCCTATTCCTCCGCCGAA
GTGCTGCACGGGCCGGTTTCCATAATCGAACGCGGATTTCCCGTGATCGCGCTCGCAGCCGCTGATCAGGCCGAAGCATG
GCTGGTGGATGTGGCCGACCAACTTGCCGCGAAAGGCGCGCATGCCTTTGTGACCTCTGACAAGACCGCGCTGGCCCGCG
CCCTGCCCTGCGCGCGCACATCGCACCTCTTGCTTGATCCGCTCGCGTTGATCGTTTCATTCTACGCCATGGTCGAACAG
GTCGCCCGGGCGCGCGGCATCAACCCCGATGCGCCGCGCCACCTCAGGAAAGTGACGGAAACACTGTGA

Upstream 100 bases:

>100_bases
CATACCTGAGCTGCGGACGGGTCGCGGAGTTCACGCAATCCACCTATCGGAAGGATGCCTATACCTTCATCGCCGAACTC
AGACTCGCCAAGGAGCCAGC

Downstream 100 bases:

>100_bases
TGAAACGCGCATATACGGGAGCGGATATCTTTGATGGCAGCACGCTCAGCTCTGACAGCGCGCTGCTGTTGGATGGCGGT
GTCTATCGCGGTGTCGTGCC

Product: SIS domain-containing protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTSQTHMRREILEIPDAVATLLTRGAPEVRAAARALQDADPAFLISVARGSSDHAATYFKYATELVAGIPVASVGPSVTS
IYGRNLRLSRGACLAISQSGKSPDIVRMAEMATAQGAVSIALTNHINSDLAGVSTHAVNLHAGVEHSVAATKTFVTSAVS
AIWLMAEWQQDHALLRALHDLPQVLKKAAHMDWSILEDEIVSSRSLFCLGRGPALAIANEAALKFKETCQLHAESYSSAE
VLHGPVSIIERGFPVIALAAADQAEAWLVDVADQLAAKGAHAFVTSDKTALARALPCARTSHLLLDPLALIVSFYAMVEQ
VARARGINPDAPRHLRKVTETL

Sequences:

>Translated_342_residues
MTSQTHMRREILEIPDAVATLLTRGAPEVRAAARALQDADPAFLISVARGSSDHAATYFKYATELVAGIPVASVGPSVTS
IYGRNLRLSRGACLAISQSGKSPDIVRMAEMATAQGAVSIALTNHINSDLAGVSTHAVNLHAGVEHSVAATKTFVTSAVS
AIWLMAEWQQDHALLRALHDLPQVLKKAAHMDWSILEDEIVSSRSLFCLGRGPALAIANEAALKFKETCQLHAESYSSAE
VLHGPVSIIERGFPVIALAAADQAEAWLVDVADQLAAKGAHAFVTSDKTALARALPCARTSHLLLDPLALIVSFYAMVEQ
VARARGINPDAPRHLRKVTETL
>Mature_341_residues
TSQTHMRREILEIPDAVATLLTRGAPEVRAAARALQDADPAFLISVARGSSDHAATYFKYATELVAGIPVASVGPSVTSI
YGRNLRLSRGACLAISQSGKSPDIVRMAEMATAQGAVSIALTNHINSDLAGVSTHAVNLHAGVEHSVAATKTFVTSAVSA
IWLMAEWQQDHALLRALHDLPQVLKKAAHMDWSILEDEIVSSRSLFCLGRGPALAIANEAALKFKETCQLHAESYSSAEV
LHGPVSIIERGFPVIALAAADQAEAWLVDVADQLAAKGAHAFVTSDKTALARALPCARTSHLLLDPLALIVSFYAMVEQV
ARARGINPDAPRHLRKVTETL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=363, Percent_Identity=26.1707988980716, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI205277386, Length=355, Percent_Identity=25.6338028169014, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1790167, Length=357, Percent_Identity=26.6106442577031, Blast_Score=104, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17532899, Length=359, Percent_Identity=26.4623955431755, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17532897, Length=359, Percent_Identity=26.4623955431755, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17539970, Length=358, Percent_Identity=27.3743016759777, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322745, Length=370, Percent_Identity=24.5945945945946, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323731, Length=217, Percent_Identity=24.8847926267281, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357745, Length=365, Percent_Identity=24.1095890410959, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 36411; Mature: 36280

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQTHMRREILEIPDAVATLLTRGAPEVRAAARALQDADPAFLISVARGSSDHAATYFK
CCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHH
YATELVAGIPVASVGPSVTSIYGRNLRLSRGACLAISQSGKSPDIVRMAEMATAQGAVSI
HHHHHHHCCCCHHCCCCHHHHHCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCEEE
ALTNHINSDLAGVSTHAVNLHAGVEHSVAATKTFVTSAVSAIWLMAEWQQDHALLRALHD
EEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPQVLKKAAHMDWSILEDEIVSSRSLFCLGRGPALAIANEAALKFKETCQLHAESYSSAE
HHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHCCCCHH
VLHGPVSIIERGFPVIALAAADQAEAWLVDVADQLAAKGAHAFVTSDKTALARALPCART
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCC
SHLLLDPLALIVSFYAMVEQVARARGINPDAPRHLRKVTETL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TSQTHMRREILEIPDAVATLLTRGAPEVRAAARALQDADPAFLISVARGSSDHAATYFK
CCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHH
YATELVAGIPVASVGPSVTSIYGRNLRLSRGACLAISQSGKSPDIVRMAEMATAQGAVSI
HHHHHHHCCCCHHCCCCHHHHHCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCEEE
ALTNHINSDLAGVSTHAVNLHAGVEHSVAATKTFVTSAVSAIWLMAEWQQDHALLRALHD
EEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPQVLKKAAHMDWSILEDEIVSSRSLFCLGRGPALAIANEAALKFKETCQLHAESYSSAE
HHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHCCCCHH
VLHGPVSIIERGFPVIALAAADQAEAWLVDVADQLAAKGAHAFVTSDKTALARALPCART
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCC
SHLLLDPLALIVSFYAMVEQVARARGINPDAPRHLRKVTETL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]