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The map label for this gene is pheA [H]

Identifier: 110678586

GI number: 110678586

Start: 1221915

End: 1222772

Strand: Reverse

Name: pheA [H]

Synonym: RD1_1261

Alternate gene names: 110678586

Gene position: 1222772-1221915 (Counterclockwise)

Preceding gene: 110678592

Following gene: 110678583

Centisome position: 29.58

GC content: 59.09

Gene sequence:

>858_bases
ATGACCCGTAAAACTGCCGTCCGCATCGCTTTTCAGGGGGCGCTTGGTGCGTATAGCCACGAGGCAGCATTGAATGCGCG
CCCCGATGCGATTCCCGTGCCATGCGCCACATTCGACGATGTGATTGCGGCGATGCACGCGGGTGATGCGGATCTCGCCA
TGCTGCCGGTGGAAAATTCAACCTATGGTCGGGTTGCGGATATTCACAGGTTGCTGCCAGAAAGCGGACTGCACATCATT
GACGAGGGGTTCGTGCGCGTTCGCATAAACCTGATGGCCCCCAAGGGTGTCAGCCTCGCAGAGGTCAGGCACATCCGCGC
CCATCTTGTCCTGATCCCGCAAGCGCGCAGTTTTCTGGATCGCCACGGGATCACTGCCGAAGCGGCCGCCGATAGCGCAG
GGGCCGCGGCGGAACTTGCGCGCCACCCCGAACCCGGCGTTGGTGCTTTGGCCAGTGCCGTGGCGGCCGACATACATGGT
CTTGATATTCTGGCCCGCGACATCGAGGACGAACATCACAACACCACCCGCTTCTTGTTGATGTCGCACGATTTGGACAA
GACACGTCGCGCGGACAAGATGATCACCACCTTTGTCTTCGAGGTCCGCAACATTCCCGCGGCCCTCTATAAGGCCATGG
GGGGGTTTGCGACCAATGGCGTCAATATGACGAAACTGGAAAGCTACATGGTCGGCGGGTCGTTCACGGCAACCCAGTTT
TATGCGGATATCGAAGGCCACCCGGATGATCCGGGCGTGCGGCGTGCCTTGGAAGAGTTGGACTATTTCACCAATATGAT
TGAAATCCTCGGTGTTTATCCCGCGCATCCGGATCGCGATCAGACGGTGGCGCGATAA

Upstream 100 bases:

>100_bases
CTTCTTGACGCGCTATCTACGTCTTCACCTTGGCCGTGGCAAGGTGTACTTACCGCGACGAAACGCCTCTTTTTTCGCAC
GAATGTATTAGGAAACCGTA

Downstream 100 bases:

>100_bases
GCGCTTTCCGTCTCGCGGGCGAAATCAGCCATGCGTTTTGCAATCTTTTGTTCCATCGTGGCTTTGGTCACCTCCAGCGC
CTTCAGAAACAGACGGCCAG

Product: prephenate dehydratase, putative

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTRKTAVRIAFQGALGAYSHEAALNARPDAIPVPCATFDDVIAAMHAGDADLAMLPVENSTYGRVADIHRLLPESGLHII
DEGFVRVRINLMAPKGVSLAEVRHIRAHLVLIPQARSFLDRHGITAEAAADSAGAAAELARHPEPGVGALASAVAADIHG
LDILARDIEDEHHNTTRFLLMSHDLDKTRRADKMITTFVFEVRNIPAALYKAMGGFATNGVNMTKLESYMVGGSFTATQF
YADIEGHPDDPGVRRALEELDYFTNMIEILGVYPAHPDRDQTVAR

Sequences:

>Translated_285_residues
MTRKTAVRIAFQGALGAYSHEAALNARPDAIPVPCATFDDVIAAMHAGDADLAMLPVENSTYGRVADIHRLLPESGLHII
DEGFVRVRINLMAPKGVSLAEVRHIRAHLVLIPQARSFLDRHGITAEAAADSAGAAAELARHPEPGVGALASAVAADIHG
LDILARDIEDEHHNTTRFLLMSHDLDKTRRADKMITTFVFEVRNIPAALYKAMGGFATNGVNMTKLESYMVGGSFTATQF
YADIEGHPDDPGVRRALEELDYFTNMIEILGVYPAHPDRDQTVAR
>Mature_284_residues
TRKTAVRIAFQGALGAYSHEAALNARPDAIPVPCATFDDVIAAMHAGDADLAMLPVENSTYGRVADIHRLLPESGLHIID
EGFVRVRINLMAPKGVSLAEVRHIRAHLVLIPQARSFLDRHGITAEAAADSAGAAAELARHPEPGVGALASAVAADIHGL
DILARDIEDEHHNTTRFLLMSHDLDKTRRADKMITTFVFEVRNIPAALYKAMGGFATNGVNMTKLESYMVGGSFTATQFY
ADIEGHPDDPGVRRALEELDYFTNMIEILGVYPAHPDRDQTVAR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=275, Percent_Identity=29.4545454545455, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30940; Mature: 30808

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKTAVRIAFQGALGAYSHEAALNARPDAIPVPCATFDDVIAAMHAGDADLAMLPVENS
CCCCEEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCC
TYGRVADIHRLLPESGLHIIDEGFVRVRINLMAPKGVSLAEVRHIRAHLVLIPQARSFLD
CCCHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCCCHHHHHHHHHHHEEEEHHHHHHHH
RHGITAEAAADSAGAAAELARHPEPGVGALASAVAADIHGLDILARDIEDEHHNTTRFLL
HCCCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
MSHDLDKTRRADKMITTFVFEVRNIPAALYKAMGGFATNGVNMTKLESYMVGGSFTATQF
EECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEHEEE
YADIEGHPDDPGVRRALEELDYFTNMIEILGVYPAHPDRDQTVAR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRKTAVRIAFQGALGAYSHEAALNARPDAIPVPCATFDDVIAAMHAGDADLAMLPVENS
CCCEEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCC
TYGRVADIHRLLPESGLHIIDEGFVRVRINLMAPKGVSLAEVRHIRAHLVLIPQARSFLD
CCCHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCCCHHHHHHHHHHHEEEEHHHHHHHH
RHGITAEAAADSAGAAAELARHPEPGVGALASAVAADIHGLDILARDIEDEHHNTTRFLL
HCCCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
MSHDLDKTRRADKMITTFVFEVRNIPAALYKAMGGFATNGVNMTKLESYMVGGSFTATQF
EECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEHEEE
YADIEGHPDDPGVRRALEELDYFTNMIEILGVYPAHPDRDQTVAR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]