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The map label for this gene is gntR [H]

Identifier: 110678272

GI number: 110678272

Start: 895831

End: 896565

Strand: Direct

Name: gntR [H]

Synonym: RD1_0925

Alternate gene names: 110678272

Gene position: 895831-896565 (Clockwise)

Preceding gene: 110678271

Following gene: 110678275

Centisome position: 21.67

GC content: 58.78

Gene sequence:

>735_bases
TTGTTACAGGATGTCCATGTCATGACCCGGATCAGCACCGTCAGATTCACGACCGATCAGCCGATTGGGGAAACCGTGCG
GATCATTGTCGAAAAGCTTTCCGTCAGGATCGAATCCGGTCAGTACCCCCCGGAATCCCGACTGCCCAGTGAGCGTGCGC
TGGCGGCGGAGCTTGGCGTGTCACGCAATACGGTGCGCGATGCGCTGGATGTCCTCGAAGCCAACGGTATGTTGCGGCGC
AGGCAGGGATCCGGGAGTTTTGTGCTGCCCCAGGGCCAGGATGCCCCCGCACCGGGATCAATCGGTGAGCGAACCGGCCC
CTTGGATCATCTGATCGTGCGCTCCATTCTGGAGCCTGAAATGATGCGGCTTGCGGTGATGAATATGTCACCCAACGACC
TCGATCAGCTGTCGCAGGTTGTGGCGCAGATCGAGGCGGTGCGCACGGATCTCAACGAATTCATCCGCCGGGAAGAGGAA
TTCTATCGCCTGATCGCCAAGGCGACGCGCAATCCCTTGCTGGAGGCGTGCTACGAGTTGACGATTGAAGTCTGCCGGCA
GAGTTTTCGCACGGCGATCATGCGCAAACACCTTACACCGGGACGCATTCAGAGCTATCAGACGCGGTTCAACTCACTGT
TCAATGCCATTGCCACGCGGGATGTGGAGGCGGCGGTCGAGATCACCAAACTGCATCTGGTGGAGGAGCAAAAACTGTTC
CTGCACGAGGGCTAA

Upstream 100 bases:

>100_bases
GAAGTGATAGGAAGGGGCCCCGGCGTTTTGTCGGGGCCCTTTGTCATTCAGGGTCATGCTATGTTCATGGCCGACAAAAT
AGGGTATCGCGCAGCAACGA

Downstream 100 bases:

>100_bases
AACGCGAAAACGTCTGCCGAATGTGTCAGGGCGACTGGCCTCCTTTTCAAAGGCAAGCCCGACCCGTGAAAAACCGCCCC
GTCGTATCAGGCCAAGGGTA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MLQDVHVMTRISTVRFTTDQPIGETVRIIVEKLSVRIESGQYPPESRLPSERALAAELGVSRNTVRDALDVLEANGMLRR
RQGSGSFVLPQGQDAPAPGSIGERTGPLDHLIVRSILEPEMMRLAVMNMSPNDLDQLSQVVAQIEAVRTDLNEFIRREEE
FYRLIAKATRNPLLEACYELTIEVCRQSFRTAIMRKHLTPGRIQSYQTRFNSLFNAIATRDVEAAVEITKLHLVEEQKLF
LHEG

Sequences:

>Translated_244_residues
MLQDVHVMTRISTVRFTTDQPIGETVRIIVEKLSVRIESGQYPPESRLPSERALAAELGVSRNTVRDALDVLEANGMLRR
RQGSGSFVLPQGQDAPAPGSIGERTGPLDHLIVRSILEPEMMRLAVMNMSPNDLDQLSQVVAQIEAVRTDLNEFIRREEE
FYRLIAKATRNPLLEACYELTIEVCRQSFRTAIMRKHLTPGRIQSYQTRFNSLFNAIATRDVEAAVEITKLHLVEEQKLF
LHEG
>Mature_244_residues
MLQDVHVMTRISTVRFTTDQPIGETVRIIVEKLSVRIESGQYPPESRLPSERALAAELGVSRNTVRDALDVLEANGMLRR
RQGSGSFVLPQGQDAPAPGSIGERTGPLDHLIVRSILEPEMMRLAVMNMSPNDLDQLSQVVAQIEAVRTDLNEFIRREEE
FYRLIAKATRNPLLEACYELTIEVCRQSFRTAIMRKHLTPGRIQSYQTRFNSLFNAIATRDVEAAVEITKLHLVEEQKLF
LHEG

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994955, Length=216, Percent_Identity=26.8518518518519, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082208, Length=215, Percent_Identity=26.9767441860465, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27623; Mature: 27623

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQDVHVMTRISTVRFTTDQPIGETVRIIVEKLSVRIESGQYPPESRLPSERALAAELGV
CCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
SRNTVRDALDVLEANGMLRRRQGSGSFVLPQGQDAPAPGSIGERTGPLDHLIVRSILEPE
CHHHHHHHHHHHHHCCHHEEECCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHH
MMRLAVMNMSPNDLDQLSQVVAQIEAVRTDLNEFIRREEEFYRLIAKATRNPLLEACYEL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TIEVCRQSFRTAIMRKHLTPGRIQSYQTRFNSLFNAIATRDVEAAVEITKLHLVEEQKLF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEG
HCCC
>Mature Secondary Structure
MLQDVHVMTRISTVRFTTDQPIGETVRIIVEKLSVRIESGQYPPESRLPSERALAAELGV
CCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
SRNTVRDALDVLEANGMLRRRQGSGSFVLPQGQDAPAPGSIGERTGPLDHLIVRSILEPE
CHHHHHHHHHHHHHCCHHEEECCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHH
MMRLAVMNMSPNDLDQLSQVVAQIEAVRTDLNEFIRREEEFYRLIAKATRNPLLEACYEL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TIEVCRQSFRTAIMRKHLTPGRIQSYQTRFNSLFNAIATRDVEAAVEITKLHLVEEQKLF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA