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The map label for this gene is araC [C]

Identifier: 110677654

GI number: 110677654

Start: 248152

End: 249030

Strand: Direct

Name: araC [C]

Synonym: RD1_0248

Alternate gene names: 110677654

Gene position: 248152-249030 (Clockwise)

Preceding gene: 110677653

Following gene: 110677655

Centisome position: 6.0

GC content: 57.34

Gene sequence:

>879_bases
ATGCCCCGACGATACGCTGACATCTACCCGTCCTCGCCACTGCTCAACAGCGATGCCATGCAACATGTCTCAGCAGCCGC
CCTGATGTCCGTGCGTTATTTTCAGGCCGAACCCGACAGCATGCCAGAAGAGGTTTTCGCCGAACATCATGTGCTGTTGA
ACCTGTGCGAGACGCCCCACCGCGTTCAGAACAGACGCGATGGCGAGTTGCGCGATTTCATGTTTCACAAAGACGAGATC
ATCGTGACGCCGGCAGGAATGAAATCCGGTTGGCGCTGGTTCGGCAAATCCGATGTGATCGTCGTGACGCTGGACCCGGC
AAAGGTGCAGAAGTTCGCGCAGAGCGAATTGGGCATCATCCTGGACAGGCAGCAGTTCGCCGATCTCCCCCAGTTCAATG
ACCCTGATTTATGCGCTGCGGGCATAATGCTGCGTGACGCGCTTGAGAATGACGATTTGACCTCCGGAGTGATGTTCGAA
GCGATGAGCCGCGTTTTGCTGGTCAAGCTGCTGCAACGATACGGTCAGAAACGTCCGGAAGAGCTGGCTTTGTCTGCCCG
TTTCACGACCGATCACTATGGTCAGGTGCTCGCGTTTATCCGCGCCAATCTGGACCGTACGATCACGGTGGATGATCTGG
CGGCTGAGGTCGGAATGTCGCCGTCGCATTTCGGCAGGGTGTTCAAGGAAACGCTGGGCCAGACGCCAATGCAATATGTT
CTCGCCTACCGGATCGAACAAGCCATCGAGATGATGAAAGAGGCAGGCCGTCCCCTGGGCATGATCGCGCTGGATTGCGG
ATTCGCGGATCAGGCGCATTTCTCGCGCAGTTTCAAACAGGTCATGGGTCAGACGCCGCGCCAATATCGCGCCCGCTGA

Upstream 100 bases:

>100_bases
TACCCGCACTTTGGAGGTGCGAATAACGGCGTATAACTCATCAGTTTGGCCAAGTTAACCAGACCTGTGATGTTCACCCG
AGGTCTGGTAGAAACACACC

Downstream 100 bases:

>100_bases
ACTGGGTCGCGCGAGACCCATGCGCCATATCAACGGCGCGCAATCGACGCAAACAGTGGAACGATGCAGGCTGGCCGAGC
CGTCATCCGGCGGACCATTG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPRRYADIYPSSPLLNSDAMQHVSAAALMSVRYFQAEPDSMPEEVFAEHHVLLNLCETPHRVQNRRDGELRDFMFHKDEI
IVTPAGMKSGWRWFGKSDVIVVTLDPAKVQKFAQSELGIILDRQQFADLPQFNDPDLCAAGIMLRDALENDDLTSGVMFE
AMSRVLLVKLLQRYGQKRPEELALSARFTTDHYGQVLAFIRANLDRTITVDDLAAEVGMSPSHFGRVFKETLGQTPMQYV
LAYRIEQAIEMMKEAGRPLGMIALDCGFADQAHFSRSFKQVMGQTPRQYRAR

Sequences:

>Translated_292_residues
MPRRYADIYPSSPLLNSDAMQHVSAAALMSVRYFQAEPDSMPEEVFAEHHVLLNLCETPHRVQNRRDGELRDFMFHKDEI
IVTPAGMKSGWRWFGKSDVIVVTLDPAKVQKFAQSELGIILDRQQFADLPQFNDPDLCAAGIMLRDALENDDLTSGVMFE
AMSRVLLVKLLQRYGQKRPEELALSARFTTDHYGQVLAFIRANLDRTITVDDLAAEVGMSPSHFGRVFKETLGQTPMQYV
LAYRIEQAIEMMKEAGRPLGMIALDCGFADQAHFSRSFKQVMGQTPRQYRAR
>Mature_291_residues
PRRYADIYPSSPLLNSDAMQHVSAAALMSVRYFQAEPDSMPEEVFAEHHVLLNLCETPHRVQNRRDGELRDFMFHKDEII
VTPAGMKSGWRWFGKSDVIVVTLDPAKVQKFAQSELGIILDRQQFADLPQFNDPDLCAAGIMLRDALENDDLTSGVMFEA
MSRVLLVKLLQRYGQKRPEELALSARFTTDHYGQVLAFIRANLDRTITVDDLAAEVGMSPSHFGRVFKETLGQTPMQYVL
AYRIEQAIEMMKEAGRPLGMIALDCGFADQAHFSRSFKQVMGQTPRQYRAR

Specific function: Binds To The Right Arm Of The Replication Origin Oric Of The E.Coli Chromosome. Rob Binding May Influence The Formation Of The Nucleoprotein Structure, Required For Oric Function In The Initiation Of Replication. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790857, Length=95, Percent_Identity=33.6842105263158, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790559, Length=121, Percent_Identity=26.4462809917355, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI226510985, Length=92, Percent_Identity=32.6086956521739, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082197, Length=253, Percent_Identity=25.6916996047431, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33178; Mature: 33046

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRRYADIYPSSPLLNSDAMQHVSAAALMSVRYFQAEPDSMPEEVFAEHHVLLNLCETPH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCH
RVQNRRDGELRDFMFHKDEIIVTPAGMKSGWRWFGKSDVIVVTLDPAKVQKFAQSELGII
HHHCCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCEE
LDRQQFADLPQFNDPDLCAAGIMLRDALENDDLTSGVMFEAMSRVLLVKLLQRYGQKRPE
ECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
ELALSARFTTDHYGQVLAFIRANLDRTITVDDLAAEVGMSPSHFGRVFKETLGQTPMQYV
HHEEHHCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
LAYRIEQAIEMMKEAGRPLGMIALDCGFADQAHFSRSFKQVMGQTPRQYRAR
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
PRRYADIYPSSPLLNSDAMQHVSAAALMSVRYFQAEPDSMPEEVFAEHHVLLNLCETPH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCH
RVQNRRDGELRDFMFHKDEIIVTPAGMKSGWRWFGKSDVIVVTLDPAKVQKFAQSELGII
HHHCCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCEE
LDRQQFADLPQFNDPDLCAAGIMLRDALENDDLTSGVMFEAMSRVLLVKLLQRYGQKRPE
ECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
ELALSARFTTDHYGQVLAFIRANLDRTITVDDLAAEVGMSPSHFGRVFKETLGQTPMQYV
HHEEHHCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
LAYRIEQAIEMMKEAGRPLGMIALDCGFADQAHFSRSFKQVMGQTPRQYRAR
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]