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The map label for this gene is accA

Identifier: 110635390

GI number: 110635390

Start: 3336401

End: 3337351

Strand: Reverse

Name: accA

Synonym: Meso_3061

Alternate gene names: 110635390

Gene position: 3337351-3336401 (Counterclockwise)

Preceding gene: 110635391

Following gene: 110635389

Centisome position: 75.63

GC content: 62.04

Gene sequence:

>951_bases
ATGTACAACTATCTCGATTTCGAAAAGCCGGTCGCCGACCTCGAAGGCAAGATCCTGGAACTGAAGAAGCTCAGCGAAAG
CGGGGAGGCGGTCGACGTTGCCGAGGAGATATCCCGGCTTGAGCGGCGCTCCAAGGACGCCTTGCGGGATGTCTACCGCG
CGCTGACCCCGTGGCAGAAGGCTCAGGTCGCCCGCCATCCCGACCGGCCCCACTGCATGGACTATGTGCGGGCGCTTTTC
ACGGATTTCACCCCGCTTGCGGGCGACCGCGCCTATGGCGAGGACGAGGCAGTGGTGGCTGGCTTTGCACGCTTCAAGGG
GCAATCCATCGCCATTGTCGGCCAGGAAAAGGGTAATGACACCCACAGCCGGCTCAAGCACAATTTCGGCATGGCGCGCC
CCGAAGGATATCGTAAGGCGGTGCGGATCATGGATCTGGCCGACCGTTTCGGCATTCCGGTCGTAAGCCTGGTGGATACC
GCGGGCGCATATCCGGGGATCGGTGCTGAGGAGCGGGGCCAGGCGGAGGCTATCGCGCGATCCACGTCGAAATGCCTAAG
CCTCAAGGTCCCCAATATTTCCGTCATCATCGGCGAGGGCGGCTCGGGCGGCGCCATCGCGATCGCCACGGCCAATCTCG
TCTATATGCTGGAGCATTCGATTTATTCGGTGATTTCGCCGGAGGGCGCCGCATCGATCTTGTGGCACGATTCCACCCGT
GCCAAAGACGCGGCGACCAATATGAAGATCACCGCGCAGGATCTTCTTCAGCTCAAGGTGATCGATGGCATCATTCCCGA
GCCGGTCGGCGGCGCGCACCGGGCTTCGGACGTCGTTATCAGGACCACCGGCGAGACGATCGAGAACGGCTTTCGCGAGC
TTGCCGAGAAGGTGGGAGATTTTCGCGAGCAGCGGCGGGAGAAGTTCCTGGCGATTGGCCGCAGCCTGTAG

Upstream 100 bases:

>100_bases
ATTAGCGTCATGACCGCTATGTGAAACCACGTTTTTTAGCGGCGTGGCGCCCTGAAAATGCCTAACCGCGGTGTCTCGTG
TCCGATTTTTTGGCGGGTGA

Downstream 100 bases:

>100_bases
GAAGCCGATTCCAAGCGGCACTTCTCAGGACTGTTCGGGGCGGAAGATATTCGTGACTTGTTATAATCTTGCCTTGTTCT
GTGCTTCAGGATAAGCGGTA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYNYLDFEKPVADLEGKILELKKLSESGEAVDVAEEISRLERRSKDALRDVYRALTPWQKAQVARHPDRPHCMDYVRALF
TDFTPLAGDRAYGEDEAVVAGFARFKGQSIAIVGQEKGNDTHSRLKHNFGMARPEGYRKAVRIMDLADRFGIPVVSLVDT
AGAYPGIGAEERGQAEAIARSTSKCLSLKVPNISVIIGEGGSGGAIAIATANLVYMLEHSIYSVISPEGAASILWHDSTR
AKDAATNMKITAQDLLQLKVIDGIIPEPVGGAHRASDVVIRTTGETIENGFRELAEKVGDFREQRREKFLAIGRSL

Sequences:

>Translated_316_residues
MYNYLDFEKPVADLEGKILELKKLSESGEAVDVAEEISRLERRSKDALRDVYRALTPWQKAQVARHPDRPHCMDYVRALF
TDFTPLAGDRAYGEDEAVVAGFARFKGQSIAIVGQEKGNDTHSRLKHNFGMARPEGYRKAVRIMDLADRFGIPVVSLVDT
AGAYPGIGAEERGQAEAIARSTSKCLSLKVPNISVIIGEGGSGGAIAIATANLVYMLEHSIYSVISPEGAASILWHDSTR
AKDAATNMKITAQDLLQLKVIDGIIPEPVGGAHRASDVVIRTTGETIENGFRELAEKVGDFREQRREKFLAIGRSL
>Mature_316_residues
MYNYLDFEKPVADLEGKILELKKLSESGEAVDVAEEISRLERRSKDALRDVYRALTPWQKAQVARHPDRPHCMDYVRALF
TDFTPLAGDRAYGEDEAVVAGFARFKGQSIAIVGQEKGNDTHSRLKHNFGMARPEGYRKAVRIMDLADRFGIPVVSLVDT
AGAYPGIGAEERGQAEAIARSTSKCLSLKVPNISVIIGEGGSGGAIAIATANLVYMLEHSIYSVISPEGAASILWHDSTR
AKDAATNMKITAQDLLQLKVIDGIIPEPVGGAHRASDVVIRTTGETIENGFRELAEKVGDFREQRREKFLAIGRSL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=47.4522292993631, Blast_Score=308, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_MESSB (Q11DU2)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_675598.1
- ProteinModelPortal:   Q11DU2
- SMR:   Q11DU2
- STRING:   Q11DU2
- GeneID:   4183315
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3061
- NMPDR:   fig|266779.1.peg.222
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q11DU2
- ProtClustDB:   PRK05724
- BioCyc:   MSP266779:MESO_3061-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34583; Mature: 34583

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNYLDFEKPVADLEGKILELKKLSESGEAVDVAEEISRLERRSKDALRDVYRALTPWQK
CCCCCCCCCCHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AQVARHPDRPHCMDYVRALFTDFTPLAGDRAYGEDEAVVAGFARFKGQSIAIVGQEKGND
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCC
THSRLKHNFGMARPEGYRKAVRIMDLADRFGIPVVSLVDTAGAYPGIGAEERGQAEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
STSKCLSLKVPNISVIIGEGGSGGAIAIATANLVYMLEHSIYSVISPEGAASILWHDSTR
HHHHHEEEECCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
AKDAATNMKITAQDLLQLKVIDGIIPEPVGGAHRASDVVIRTTGETIENGFRELAEKVGD
CHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
FREQRREKFLAIGRSL
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYNYLDFEKPVADLEGKILELKKLSESGEAVDVAEEISRLERRSKDALRDVYRALTPWQK
CCCCCCCCCCHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AQVARHPDRPHCMDYVRALFTDFTPLAGDRAYGEDEAVVAGFARFKGQSIAIVGQEKGND
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCC
THSRLKHNFGMARPEGYRKAVRIMDLADRFGIPVVSLVDTAGAYPGIGAEERGQAEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
STSKCLSLKVPNISVIIGEGGSGGAIAIATANLVYMLEHSIYSVISPEGAASILWHDSTR
HHHHHEEEECCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
AKDAATNMKITAQDLLQLKVIDGIIPEPVGGAHRASDVVIRTTGETIENGFRELAEKVGD
CHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
FREQRREKFLAIGRSL
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA