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The map label for this gene is xerD [H]

Identifier: 110635391

GI number: 110635391

Start: 3337447

End: 3338373

Strand: Reverse

Name: xerD [H]

Synonym: Meso_3062

Alternate gene names: 110635391

Gene position: 3338373-3337447 (Counterclockwise)

Preceding gene: 110635392

Following gene: 110635390

Centisome position: 75.66

GC content: 63.43

Gene sequence:

>927_bases
ATGGCGAGCGGCGCGAAGATTGAAGCGTTTCTGGAGATGATGGCGGCCGAGCGGGGCGCGAGCGACAACACACTCGCCTC
ATATCGCCGGGATCTGGGAGACGCGGACGCTTACCTCGAAGCGCCTTGCGGCGGGGTTTTCAAGGCGAGCGCCGCTGATA
TCCGCAAATACCTCGCGGACATGACTGCGCGCGGCTTCGCCTCGACAACCCAGGCGCGCAAGCTTTCTTCGCTGCGTCAG
TTCTTCAAGTTCCTTTATTCCGAAGGCATGCGCGACGATGATCCCACCGGCGTGCTCGACAGCCCGAAGAAGGGCCGCCC
CCTGCCCAAGACGCTAAGCGAATCGGAAATGAACGCGCTTCTCGAAAGGGCAGCGGACGAGGCACGAGAGGCGCCAGCGG
GCACGCCCGCGCGCGTCGCTGCCCAACGGCTCTCAACGCTCCTGGAAATGCTTTATGCCTCGGGTCTGCGCGTTTCGGAA
TTGGTCAGCCTGCCGCTCAGAGTGGCTCTAAGGGACGAGCGCTTCTTCACCGTGCGGGGAAAGGGAGGCAAGGAGCGCAT
GGTTCCGCTTTCCGCCAAGGCGCGTGAAGCGGTGGCCTTGTGGCTCAAGGAGCGGGCGCGGCATCCCTCTTTCGCGAACA
GCCCCTGGCTGTTCCCGGCGGTATCGGCAAGCGGATACCTCTCTCGTCAGGTCTTCGCGCGCGAGCTTAAGGGCCTGGCC
GGACGCGCGGGAATTTCAACGGCCAAAATCTCCCCACATGTGCTGCGCCATGCCTTTGCCAGCCACCTGCTGCAGAACGG
CGCGGATCTGCGCGCCGTGCAGCAATTGCTTGGCCACGCCGACATCTCGACCACGCAGATCTATACCCACGTGCTGGAAA
AACGGCTGCAGGAACTGGTGCAGAAGCACCACCCGCTTGCCGATTAG

Upstream 100 bases:

>100_bases
CCGGAACGGCTCGACCGGCGGTGAATGCCTGCCGCCAGCGCTGTTTGGAAATTGTTTGCGTTCTTCGCTTAGTAATTTCG
ACTTGCAAGGCAGGATGAAA

Downstream 100 bases:

>100_bases
CGTCATGACCGCTATGTGAAACCACGTTTTTTAGCGGCGTGGCGCCCTGAAAATGCCTAACCGCGGTGTCTCGTGTCCGA
TTTTTTGGCGGGTGAATGTA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MASGAKIEAFLEMMAAERGASDNTLASYRRDLGDADAYLEAPCGGVFKASAADIRKYLADMTARGFASTTQARKLSSLRQ
FFKFLYSEGMRDDDPTGVLDSPKKGRPLPKTLSESEMNALLERAADEAREAPAGTPARVAAQRLSTLLEMLYASGLRVSE
LVSLPLRVALRDERFFTVRGKGGKERMVPLSAKAREAVALWLKERARHPSFANSPWLFPAVSASGYLSRQVFARELKGLA
GRAGISTAKISPHVLRHAFASHLLQNGADLRAVQQLLGHADISTTQIYTHVLEKRLQELVQKHHPLAD

Sequences:

>Translated_308_residues
MASGAKIEAFLEMMAAERGASDNTLASYRRDLGDADAYLEAPCGGVFKASAADIRKYLADMTARGFASTTQARKLSSLRQ
FFKFLYSEGMRDDDPTGVLDSPKKGRPLPKTLSESEMNALLERAADEAREAPAGTPARVAAQRLSTLLEMLYASGLRVSE
LVSLPLRVALRDERFFTVRGKGGKERMVPLSAKAREAVALWLKERARHPSFANSPWLFPAVSASGYLSRQVFARELKGLA
GRAGISTAKISPHVLRHAFASHLLQNGADLRAVQQLLGHADISTTQIYTHVLEKRLQELVQKHHPLAD
>Mature_307_residues
ASGAKIEAFLEMMAAERGASDNTLASYRRDLGDADAYLEAPCGGVFKASAADIRKYLADMTARGFASTTQARKLSSLRQF
FKFLYSEGMRDDDPTGVLDSPKKGRPLPKTLSESEMNALLERAADEAREAPAGTPARVAAQRLSTLLEMLYASGLRVSEL
VSLPLRVALRDERFFTVRGKGGKERMVPLSAKAREAVALWLKERARHPSFANSPWLFPAVSASGYLSRQVFARELKGLAG
RAGISTAKISPHVLRHAFASHLLQNGADLRAVQQLLGHADISTTQIYTHVLEKRLQELVQKHHPLAD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=313, Percent_Identity=43.4504792332268, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1790244, Length=310, Percent_Identity=31.9354838709677, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790768, Length=145, Percent_Identity=35.8620689655172, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=33.8888888888889, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33731; Mature: 33600

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGAKIEAFLEMMAAERGASDNTLASYRRDLGDADAYLEAPCGGVFKASAADIRKYLAD
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
MTARGFASTTQARKLSSLRQFFKFLYSEGMRDDDPTGVLDSPKKGRPLPKTLSESEMNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LERAADEAREAPAGTPARVAAQRLSTLLEMLYASGLRVSELVSLPLRVALRDERFFTVRG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCEEEEEEC
KGGKERMVPLSAKAREAVALWLKERARHPSFANSPWLFPAVSASGYLSRQVFARELKGLA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GRAGISTAKISPHVLRHAFASHLLQNGADLRAVQQLLGHADISTTQIYTHVLEKRLQELV
CCCCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
QKHHPLAD
HHCCCCCC
>Mature Secondary Structure 
ASGAKIEAFLEMMAAERGASDNTLASYRRDLGDADAYLEAPCGGVFKASAADIRKYLAD
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
MTARGFASTTQARKLSSLRQFFKFLYSEGMRDDDPTGVLDSPKKGRPLPKTLSESEMNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LERAADEAREAPAGTPARVAAQRLSTLLEMLYASGLRVSELVSLPLRVALRDERFFTVRG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCEEEEEEC
KGGKERMVPLSAKAREAVALWLKERARHPSFANSPWLFPAVSASGYLSRQVFARELKGLA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GRAGISTAKISPHVLRHAFASHLLQNGADLRAVQQLLGHADISTTQIYTHVLEKRLQELV
CCCCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
QKHHPLAD
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]