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The map label for this gene is siaP [H]

Identifier: 110634860

GI number: 110634860

Start: 2697534

End: 2698526

Strand: Reverse

Name: siaP [H]

Synonym: Meso_2519

Alternate gene names: 110634860

Gene position: 2698526-2697534 (Counterclockwise)

Preceding gene: 110634861

Following gene: 110634859

Centisome position: 61.16

GC content: 57.4

Gene sequence:

>993_bases
ATGAGACTTTTTACCATAACTGCTTGCGGTATTCTGGCCGCGCTCACCATGACGGGATCGGCCCTTGCAGATGAGGTGTC
TATCCGCCTTGGGCATGTTGGTGCGCCGGTAAGCCCCCAGCAGACGATCGCTGAGCTTTTTGCCTCCAAGGTCGAAGAAT
ACAGCGATGGCAGCGTCACCGTGCAGATTTTCAATTCCGGGACGCTGGGCAACGAACGCCAACTTCAGGAAGGCGTGCGC
AGCAGCACGCTCGACATGACGATCGCCGGGACGTTTTCCTATTTCGTCCCTTGGGCCGGTGCACTTGAGGCGCCGATGCT
TTATTCGAGCCTCGAGCATTTCACCAACTTCTTCTCGAGTGAGGATGGTGCGAAGCTTATGGAGGCATTTCAGGCCGATG
CCGATGTGAAAGCTCTGTTCGTCGTTCCCCACGGCGGATTCCGCTATATCACTATGCGCGATATCGAGGTCAAAAGCCCG
GCCGACCTTAAAGGCGTCAAGATCCGTAACCCGAACGTGCCGTCATTCAATGTGATGGCCGAGGCGGTTGGGGCGATTCC
GACACCGATCGATTTTTCTGAACTCTATGTCGCGCTTCAACGCGACGTGGTGCAGGGCCAGCATAACCCGGTGGGAAATA
TCGTCGGCGCCAAACTCTATGAAGTGCAGGACTCCCTGTCGATGGTTCCCTGGGGTATCTCGCCTCACCTGGTATCAATG
AGCACCCGCGCCTGGGAACGCTTGGACGATGCCCAAAAAGAAGCTGTCGTCCGCGCTTCCGCGGAGACCGCCAAGGAATA
CCCCGCTATCGCCGTCGCTGAAGAGGAGGAGCTGCTTTCCGGGATCGAGGAGCAGATCACAATCATCCGCCCGGATGAGA
TCGACCTCGAGGCTTTTCTCGCCACTTTCCGCGACACTGGTCTGCCAGCACTTAAAAATGAATATGGCGATGCCGCGGGC
AAGTGGCTCGATGCCATCGACGCAGCCCGCTGA

Upstream 100 bases:

>100_bases
CGGTCAGAAACCACTTCGAGATCGGGCGGGCGATCAGGATGAGGATGTCCGTCCACCGAGCCTGAGACAGGCAAATTTAC
AACCCAGCCGGGAGGAAAGT

Downstream 100 bases:

>100_bases
GTTACGCACAGGCGGAGAGTGCTAACCGCTCTCCGCCTAGCCCAAGGTAAAACTCCATGTCACTAGAAGCGTTCTACGCG
GTGAGCGCGCTCATCGTGTT

Product: TRAP dicarboxylate transporter, DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRLFTITACGILAALTMTGSALADEVSIRLGHVGAPVSPQQTIAELFASKVEEYSDGSVTVQIFNSGTLGNERQLQEGVR
SSTLDMTIAGTFSYFVPWAGALEAPMLYSSLEHFTNFFSSEDGAKLMEAFQADADVKALFVVPHGGFRYITMRDIEVKSP
ADLKGVKIRNPNVPSFNVMAEAVGAIPTPIDFSELYVALQRDVVQGQHNPVGNIVGAKLYEVQDSLSMVPWGISPHLVSM
STRAWERLDDAQKEAVVRASAETAKEYPAIAVAEEEELLSGIEEQITIIRPDEIDLEAFLATFRDTGLPALKNEYGDAAG
KWLDAIDAAR

Sequences:

>Translated_330_residues
MRLFTITACGILAALTMTGSALADEVSIRLGHVGAPVSPQQTIAELFASKVEEYSDGSVTVQIFNSGTLGNERQLQEGVR
SSTLDMTIAGTFSYFVPWAGALEAPMLYSSLEHFTNFFSSEDGAKLMEAFQADADVKALFVVPHGGFRYITMRDIEVKSP
ADLKGVKIRNPNVPSFNVMAEAVGAIPTPIDFSELYVALQRDVVQGQHNPVGNIVGAKLYEVQDSLSMVPWGISPHLVSM
STRAWERLDDAQKEAVVRASAETAKEYPAIAVAEEEELLSGIEEQITIIRPDEIDLEAFLATFRDTGLPALKNEYGDAAG
KWLDAIDAAR
>Mature_330_residues
MRLFTITACGILAALTMTGSALADEVSIRLGHVGAPVSPQQTIAELFASKVEEYSDGSVTVQIFNSGTLGNERQLQEGVR
SSTLDMTIAGTFSYFVPWAGALEAPMLYSSLEHFTNFFSSEDGAKLMEAFQADADVKALFVVPHGGFRYITMRDIEVKSP
ADLKGVKIRNPNVPSFNVMAEAVGAIPTPIDFSELYVALQRDVVQGQHNPVGNIVGAKLYEVQDSLSMVPWGISPHLVSM
STRAWERLDDAQKEAVVRASAETAKEYPAIAVAEEEELLSGIEEQITIIRPDEIDLEAFLATFRDTGLPALKNEYGDAAG
KWLDAIDAAR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=306, Percent_Identity=31.6993464052288, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 35807; Mature: 35807

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFTITACGILAALTMTGSALADEVSIRLGHVGAPVSPQQTIAELFASKVEEYSDGSVT
CEEEEEEHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEE
VQIFNSGTLGNERQLQEGVRSSTLDMTIAGTFSYFVPWAGALEAPMLYSSLEHFTNFFSS
EEEEECCCCCCHHHHHHHHHHCCCEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
EDGAKLMEAFQADADVKALFVVPHGGFRYITMRDIEVKSPADLKGVKIRNPNVPSFNVMA
CCHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCEEECCCCCCCHHHHH
EAVGAIPTPIDFSELYVALQRDVVQGQHNPVGNIVGAKLYEVQDSLSMVPWGISPHLVSM
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
STRAWERLDDAQKEAVVRASAETAKEYPAIAVAEEEELLSGIEEQITIIRPDEIDLEAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHCCHHHCEEEECCCCCCHHHHH
ATFRDTGLPALKNEYGDAAGKWLDAIDAAR
HHHHHCCCCHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLFTITACGILAALTMTGSALADEVSIRLGHVGAPVSPQQTIAELFASKVEEYSDGSVT
CEEEEEEHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEE
VQIFNSGTLGNERQLQEGVRSSTLDMTIAGTFSYFVPWAGALEAPMLYSSLEHFTNFFSS
EEEEECCCCCCHHHHHHHHHHCCCEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
EDGAKLMEAFQADADVKALFVVPHGGFRYITMRDIEVKSPADLKGVKIRNPNVPSFNVMA
CCHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCEEECCCCCCCHHHHH
EAVGAIPTPIDFSELYVALQRDVVQGQHNPVGNIVGAKLYEVQDSLSMVPWGISPHLVSM
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
STRAWERLDDAQKEAVVRASAETAKEYPAIAVAEEEELLSGIEEQITIIRPDEIDLEAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHCCHHHCEEEECCCCCCHHHHH
ATFRDTGLPALKNEYGDAAGKWLDAIDAAR
HHHHHCCCCHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA