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The map label for this gene is prmA

Identifier: 110634343

GI number: 110634343

Start: 2135609

End: 2136481

Strand: Direct

Name: prmA

Synonym: Meso_1993

Alternate gene names: 110634343

Gene position: 2135609-2136481 (Clockwise)

Preceding gene: 110634342

Following gene: 110634344

Centisome position: 48.4

GC content: 61.97

Gene sequence:

>873_bases
ATGCCTCAGACACGCCTCTTTTTTCGCTCGAACGGCGCCCCCGCCAGGGAAGCATTTTCCCGGCTGGAAGCGGCATTCGA
AGAGGATGGCCTTCCGCTCGCTATCCGCGAGCTTGATGAGGAGCGCGACATCCACGAGGTCTCCATCTATGCTTCCGAGG
ATTGGGAAGGCGTGGCCGATCGCATGCGTTCATGCCTTACTTCCATTGCCGGCCTGAGCGAGATCGAGACGGAAGAACTG
CCGGAGATCGACTGGGTCGCTCATTCGCTGGCTGGCCTCAAGGCGGTGCGCGCTGGCCGCTTCTTCGTTCATGGTTCCCA
TGAAAGAGGGCAACACCGCGCCGGCGAGATCCCCATCGAGATTGAAGCAAGCCTCGCCTTCGGCACCGGCCATCACGGAA
CCACCTCCGGCTGCCTGGAAATGATCAGCCGTGTGGTCCCGCGCGAGCATCCACGAAATGCGCTTGACCTTGGGACGGGC
AGCGCTGTCCTTGCCATCGCGATCGCGCGCCTGGCGCATATCCCGGTGCTCGCCACCGATATCGACCCGGTAGCCGTGCG
CGTGGCTCGCGAGAATGTACGGCTGAACCGAGCGGCGGAATGGGTCGAGACCGCCGCTGCCCCAGGCTTTCATCACCCGG
CTTTTGCGCGCCGCATGCCCTTCGACCTTATTGTGGCGAATATCCTTGCCCGACCGCTTATCGGATTGGCGCCGGCAATG
GCGCGTCACCTTTCGCCAGGCGGCTCGCTGATCCTTTCGGGTATTCTCACACACCAGCGCCGCCAAGTCATTGCCGGCTA
TGTTGGCCAAGGCTTCAGGCACCTCACCACGCTTCATCGCGAAGAATGGGTTACCATCCATATGAAGCGTTGA

Upstream 100 bases:

>100_bases
CTTCGGCACCATATCCTACGAAGAGAACCAGGAAACGGCTATCGCAAAGCTTCGCCGGCTGATAAGGGAAGGCTGATCCG
CCTCATTCTCATCTCCCCCA

Downstream 100 bases:

>100_bases
TCACAAACAAAAAGCGGCCGTTTCCAGCCGCCTTCTTCAATCTATCTGAGCAGAAGTCAGTAAGGAAATGCGGAACTCCT
GCGCTGCAGCTCCTTACGGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MPQTRLFFRSNGAPAREAFSRLEAAFEEDGLPLAIRELDEERDIHEVSIYASEDWEGVADRMRSCLTSIAGLSEIETEEL
PEIDWVAHSLAGLKAVRAGRFFVHGSHERGQHRAGEIPIEIEASLAFGTGHHGTTSGCLEMISRVVPREHPRNALDLGTG
SAVLAIAIARLAHIPVLATDIDPVAVRVARENVRLNRAAEWVETAAAPGFHHPAFARRMPFDLIVANILARPLIGLAPAM
ARHLSPGGSLILSGILTHQRRQVIAGYVGQGFRHLTTLHREEWVTIHMKR

Sequences:

>Translated_290_residues
MPQTRLFFRSNGAPAREAFSRLEAAFEEDGLPLAIRELDEERDIHEVSIYASEDWEGVADRMRSCLTSIAGLSEIETEEL
PEIDWVAHSLAGLKAVRAGRFFVHGSHERGQHRAGEIPIEIEASLAFGTGHHGTTSGCLEMISRVVPREHPRNALDLGTG
SAVLAIAIARLAHIPVLATDIDPVAVRVARENVRLNRAAEWVETAAAPGFHHPAFARRMPFDLIVANILARPLIGLAPAM
ARHLSPGGSLILSGILTHQRRQVIAGYVGQGFRHLTTLHREEWVTIHMKR
>Mature_289_residues
PQTRLFFRSNGAPAREAFSRLEAAFEEDGLPLAIRELDEERDIHEVSIYASEDWEGVADRMRSCLTSIAGLSEIETEELP
EIDWVAHSLAGLKAVRAGRFFVHGSHERGQHRAGEIPIEIEASLAFGTGHHGTTSGCLEMISRVVPREHPRNALDLGTGS
AVLAIAIARLAHIPVLATDIDPVAVRVARENVRLNRAAEWVETAAAPGFHHPAFARRMPFDLIVANILARPLIGLAPAMA
RHLSPGGSLILSGILTHQRRQVIAGYVGQGFRHLTTLHREEWVTIHMKR

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=213, Percent_Identity=30.9859154929577, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_MESSB (Q11GT9)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674551.1
- ProteinModelPortal:   Q11GT9
- SMR:   Q11GT9
- STRING:   Q11GT9
- GeneID:   4182080
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1993
- NMPDR:   fig|266779.1.peg.588
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   GHHGTTL
- PhylomeDB:   Q11GT9
- ProtClustDB:   PRK00517
- BioCyc:   MSP266779:MESO_1993-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31908; Mature: 31777

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTRLFFRSNGAPAREAFSRLEAAFEEDGLPLAIRELDEERDIHEVSIYASEDWEGVAD
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEECCCHHHHHH
RMRSCLTSIAGLSEIETEELPEIDWVAHSLAGLKAVRAGRFFVHGSHERGQHRAGEIPIE
HHHHHHHHHHCHHHCCHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEE
IEASLAFGTGHHGTTSGCLEMISRVVPREHPRNALDLGTGSAVLAIAIARLAHIPVLATD
EEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
IDPVAVRVARENVRLNRAAEWVETAAAPGFHHPAFARRMPFDLIVANILARPLIGLAPAM
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
ARHLSPGGSLILSGILTHQRRQVIAGYVGQGFRHLTTLHREEWVTIHMKR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure 
PQTRLFFRSNGAPAREAFSRLEAAFEEDGLPLAIRELDEERDIHEVSIYASEDWEGVAD
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEECCCHHHHHH
RMRSCLTSIAGLSEIETEELPEIDWVAHSLAGLKAVRAGRFFVHGSHERGQHRAGEIPIE
HHHHHHHHHHCHHHCCHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEE
IEASLAFGTGHHGTTSGCLEMISRVVPREHPRNALDLGTGSAVLAIAIARLAHIPVLATD
EEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
IDPVAVRVARENVRLNRAAEWVETAAAPGFHHPAFARRMPFDLIVANILARPLIGLAPAM
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
ARHLSPGGSLILSGILTHQRRQVIAGYVGQGFRHLTTLHREEWVTIHMKR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA