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The map label for this gene is rhmD [H]

Identifier: 110634306

GI number: 110634306

Start: 2097141

End: 2098298

Strand: Direct

Name: rhmD [H]

Synonym: Meso_1956

Alternate gene names: 110634306

Gene position: 2097141-2098298 (Clockwise)

Preceding gene: 110634305

Following gene: 110634307

Centisome position: 47.53

GC content: 63.99

Gene sequence:

>1158_bases
ATGCAATTCGACAAGGACATGGAAATCACCCGGATCGGTGTGCGGGTGTTCTCCTATACATCGCAGATCCGGCGGGCCTT
CGGGCATTCGCATCCCGGACCAGCCAATACCGCCCGGCAGACGCTGCTCGAAATCGAGACGCGCGGCGGCGCCAAGGGCT
ATGCCTTCGGCATGCAGCCCGAACTGGTGGACCGCGTGTTGGTGCCGATGCTGATCGGCGAAAATGCGCTCTATCGCGAA
AAGATCTGGCAGAAGCTCTCCGAGCTGCAGCGCGGCAACGGCGCGACGCTGAGCGACGCGATGATGGCGCTGGTCGATGT
GGCGCTGTGGGATCTGGCCGGCCGTGCGGTAGGGCTGCCAGTTCAGCAATTGCTCGGCGCTTTTCGCGACAAGATCCCGG
CCTATGCCAGCACCATGGTGGGCGATGCCGACCTCAAGGGCGGGCTGACCAGCCCCGAGGCCTATGCCGATTTCGCCATC
CAGTGCAAGGAAGAGGGCTATACCGCCTACAAGATGCACCCCTGGATGCCGCCGGTACCCGGCGCCCCCTCCGTCGACCG
CGACCTGGCCATGGCCACTGCGGTGCGCAAGGCTGTCGGGCCCGAGATGCACCTGATGTTCGACCCTTATCACCAGTATA
GCCGGCAGGAGGCCAAGCGGCTCGGTCGAGGCCTCGAGGAACTCGGGTTTCTGTGGATGGAAGAGCCGATGCGCGAGGCC
AGCATCAGCTCCTATCGCTGGCTCTGCGATGAGCTCGACCTGCCGATCTGCGGTCCCGAAACTGCGCCGGGGCAGATCTG
GACCCGGGCCGAATGGGTGCTGGCGGGCGCCTGCGATATCCTGCGCACCGGCGTGCTTGATGTCGGCGGCATCACGCCGA
TGATGAAGACCATCCATCTGGCCGAAGCCCATGGCATGTCGATCGAGCTCCATCAGAACGGCGCTGCGACGCTGCATGCG
CTTGGTGCCATGCAGATCCCCGGCCGTTTCTATGAACGCGGCCTGCTGCATCCGCTTATCAAGTACGAATCCAAGACGCC
GTGGCTGGCCACCATCGACGACCCGATGGACGCCGAGGGCTTCGTGCATGTTCCCAAGGGGCCGGGCATGGGCTGGGATA
TCGACTGGGACTTCATCGCCGGCAACGAGATCAAGTGA

Upstream 100 bases:

>100_bases
CGATCCGCCTGATCGGCGACAATATCGGCCGGTTGATGCGGGGTGAACCCCTGATCAACGAAGTGGCCCCCCACGACCTC
AAGAAAATGGCGGTTTGACT

Downstream 100 bases:

>100_bases
GCCGGTCATGATGCGCGTGGGGATCGTGGGAACCGCCTTTGGCGAATCCCGCTGCCGGATGCTGGCCGCGGTGCCGCAGG
CGCAGTTGATCGCCGTCTGC

Product: mandelate racemase/muconate lactonizing-like protein

Products: NA

Alternate protein names: RhamD [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQFDKDMEITRIGVRVFSYTSQIRRAFGHSHPGPANTARQTLLEIETRGGAKGYAFGMQPELVDRVLVPMLIGENALYRE
KIWQKLSELQRGNGATLSDAMMALVDVALWDLAGRAVGLPVQQLLGAFRDKIPAYASTMVGDADLKGGLTSPEAYADFAI
QCKEEGYTAYKMHPWMPPVPGAPSVDRDLAMATAVRKAVGPEMHLMFDPYHQYSRQEAKRLGRGLEELGFLWMEEPMREA
SISSYRWLCDELDLPICGPETAPGQIWTRAEWVLAGACDILRTGVLDVGGITPMMKTIHLAEAHGMSIELHQNGAATLHA
LGAMQIPGRFYERGLLHPLIKYESKTPWLATIDDPMDAEGFVHVPKGPGMGWDIDWDFIAGNEIK

Sequences:

>Translated_385_residues
MQFDKDMEITRIGVRVFSYTSQIRRAFGHSHPGPANTARQTLLEIETRGGAKGYAFGMQPELVDRVLVPMLIGENALYRE
KIWQKLSELQRGNGATLSDAMMALVDVALWDLAGRAVGLPVQQLLGAFRDKIPAYASTMVGDADLKGGLTSPEAYADFAI
QCKEEGYTAYKMHPWMPPVPGAPSVDRDLAMATAVRKAVGPEMHLMFDPYHQYSRQEAKRLGRGLEELGFLWMEEPMREA
SISSYRWLCDELDLPICGPETAPGQIWTRAEWVLAGACDILRTGVLDVGGITPMMKTIHLAEAHGMSIELHQNGAATLHA
LGAMQIPGRFYERGLLHPLIKYESKTPWLATIDDPMDAEGFVHVPKGPGMGWDIDWDFIAGNEIK
>Mature_385_residues
MQFDKDMEITRIGVRVFSYTSQIRRAFGHSHPGPANTARQTLLEIETRGGAKGYAFGMQPELVDRVLVPMLIGENALYRE
KIWQKLSELQRGNGATLSDAMMALVDVALWDLAGRAVGLPVQQLLGAFRDKIPAYASTMVGDADLKGGLTSPEAYADFAI
QCKEEGYTAYKMHPWMPPVPGAPSVDRDLAMATAVRKAVGPEMHLMFDPYHQYSRQEAKRLGRGLEELGFLWMEEPMREA
SISSYRWLCDELDLPICGPETAPGQIWTRAEWVLAGACDILRTGVLDVGGITPMMKTIHLAEAHGMSIELHQNGAATLHA
LGAMQIPGRFYERGLLHPLIKYESKTPWLATIDDPMDAEGFVHVPKGPGMGWDIDWDFIAGNEIK

Specific function: Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR) [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787864, Length=274, Percent_Identity=25.1824817518248, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI226510960, Length=378, Percent_Identity=23.2804232804233, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI48994953, Length=290, Percent_Identity=26.551724137931, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.90 [H]

Molecular weight: Translated: 42655; Mature: 42655

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKDMEITRIGVRVFSYTSQIRRAFGHSHPGPANTARQTLLEIETRGGAKGYAFGMQP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCH
ELVDRVLVPMLIGENALYREKIWQKLSELQRGNGATLSDAMMALVDVALWDLAGRAVGLP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
VQQLLGAFRDKIPAYASTMVGDADLKGGLTSPEAYADFAIQCKEEGYTAYKMHPWMPPVP
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHEEEECCCCCEEEEECCCCCCCC
GAPSVDRDLAMATAVRKAVGPEMHLMFDPYHQYSRQEAKRLGRGLEELGFLWMEEPMREA
CCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SISSYRWLCDELDLPICGPETAPGQIWTRAEWVLAGACDILRTGVLDVGGITPMMKTIHL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AEAHGMSIELHQNGAATLHALGAMQIPGRFYERGLLHPLIKYESKTPWLATIDDPMDAEG
HHHCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
FVHVPKGPGMGWDIDWDFIAGNEIK
EEECCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MQFDKDMEITRIGVRVFSYTSQIRRAFGHSHPGPANTARQTLLEIETRGGAKGYAFGMQP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCH
ELVDRVLVPMLIGENALYREKIWQKLSELQRGNGATLSDAMMALVDVALWDLAGRAVGLP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
VQQLLGAFRDKIPAYASTMVGDADLKGGLTSPEAYADFAIQCKEEGYTAYKMHPWMPPVP
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHEEEECCCCCEEEEECCCCCCCC
GAPSVDRDLAMATAVRKAVGPEMHLMFDPYHQYSRQEAKRLGRGLEELGFLWMEEPMREA
CCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SISSYRWLCDELDLPICGPETAPGQIWTRAEWVLAGACDILRTGVLDVGGITPMMKTIHL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AEAHGMSIELHQNGAATLHALGAMQIPGRFYERGLLHPLIKYESKTPWLATIDDPMDAEG
HHHCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
FVHVPKGPGMGWDIDWDFIAGNEIK
EEECCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA