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The map label for this gene is 110634197

Identifier: 110634197

GI number: 110634197

Start: 1983646

End: 1984719

Strand: Reverse

Name: 110634197

Synonym: Meso_1847

Alternate gene names: NA

Gene position: 1984719-1983646 (Counterclockwise)

Preceding gene: 110634198

Following gene: 110634196

Centisome position: 44.98

GC content: 58.94

Gene sequence:

>1074_bases
ATGTCGTACTACGAATTGTCCGCCGATGAGGATTTGAACATCCTTAGACTGCATGAAAAGGCGATTGTGTTCGACGGTGC
CTTCCCGATGCTCGGCTTCTACAAGGCGCCTGAGGAGGAAATCGACGCTTTCCTTAAGGGCGGCGTGACGGGCGGGAACG
CGACGCTCTCTTCCGACGAGACCGATTTCTCCGGCGCGATCGCGAATTTCCGCAACCTGAAGGCTCTCATTTCGCGCAAT
AGCGATCGGATGGCCCTTTGCACCCGTGCGGCCGATATCGAGCGTTGCAAGCGGGACGGCAAGATTGGCATGGTTCCCTT
CTTCCAGAATCCCAAGCCGATTGCCGACCGGCTGGCCGATCTGGAGATTTTCTACGAGCTGGGCCTGCGCGTATTCCAGA
TGACATACAACAATCTGGGCTTCATCGGCGCCGGCTGTTGCGAGCGCAACGATCCGGGGCTGAGCAATTTCGGCATCGAG
GTGGTGAGCAAATGCAACGAGCTCGGCATTCTGCTAGACATCTCCCATTGCGGGCCGGCGACATCCTGGGACACGCTGAA
GTTTTCCAAGGCGCCCGTGGTCGCCAGCCATTCGGGTGCATATGCCCTTGCGCGCGCCTTCGGGCGCAATAAGCCCGACG
ACATGTTAAAGGCGGTGGCTGACACGGGTGGACTGGCAGGCATTCCCTTCTTCCCCTGCCTCGTGAAGAGAGATCCGGAG
ACGCATGTCGTGCAGCCCTCCACCGTCGAGGACGTCATCGACCATATCGACCACGCCGTCGAGATCATGGGCATAGACCA
TGTTGGAATTGCTTCCGACATGTCCTCCCATCTGGCGCGTACCCTGGAGCTTACGCGAGACTCGGTGCTGCGCACCACGC
GACTGCGTCATCCGGAGGTTTTCGGCGTCGGGCCTACCGATCGCTACGATCCTTATCCGGCAGGTTTAGACAGCCATGCC
AAAATGCTGAACCTCAGCCGCGGGCTCCACAAACGCGGCTATGCCGAAGGCGATATCATAAAGATACTCGGGGGGAACTG
GATGCGCGTCTACAGCGCAGTGTGGAAGGACTAG

Upstream 100 bases:

>100_bases
ACCCCGTGCCTCAATGCATTGGCGAAATGCTCCAGCTTGGAGTGAACTCCAATATGGGTTCCGGTCGGAATTCGAGATGC
AGCAGCCGCAAGAGGGAGTG

Downstream 100 bases:

>100_bases
AGGGGAAGGCAGGGTGAACCTGACCGTCACAAAAACCGACAAGGGGAATTCGTGAGGAGAACAATGCGATGAACACATCC
ATTCTCAACCGGCTGCGGCG

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSYYELSADEDLNILRLHEKAIVFDGAFPMLGFYKAPEEEIDAFLKGGVTGGNATLSSDETDFSGAIANFRNLKALISRN
SDRMALCTRAADIERCKRDGKIGMVPFFQNPKPIADRLADLEIFYELGLRVFQMTYNNLGFIGAGCCERNDPGLSNFGIE
VVSKCNELGILLDISHCGPATSWDTLKFSKAPVVASHSGAYALARAFGRNKPDDMLKAVADTGGLAGIPFFPCLVKRDPE
THVVQPSTVEDVIDHIDHAVEIMGIDHVGIASDMSSHLARTLELTRDSVLRTTRLRHPEVFGVGPTDRYDPYPAGLDSHA
KMLNLSRGLHKRGYAEGDIIKILGGNWMRVYSAVWKD

Sequences:

>Translated_357_residues
MSYYELSADEDLNILRLHEKAIVFDGAFPMLGFYKAPEEEIDAFLKGGVTGGNATLSSDETDFSGAIANFRNLKALISRN
SDRMALCTRAADIERCKRDGKIGMVPFFQNPKPIADRLADLEIFYELGLRVFQMTYNNLGFIGAGCCERNDPGLSNFGIE
VVSKCNELGILLDISHCGPATSWDTLKFSKAPVVASHSGAYALARAFGRNKPDDMLKAVADTGGLAGIPFFPCLVKRDPE
THVVQPSTVEDVIDHIDHAVEIMGIDHVGIASDMSSHLARTLELTRDSVLRTTRLRHPEVFGVGPTDRYDPYPAGLDSHA
KMLNLSRGLHKRGYAEGDIIKILGGNWMRVYSAVWKD
>Mature_356_residues
SYYELSADEDLNILRLHEKAIVFDGAFPMLGFYKAPEEEIDAFLKGGVTGGNATLSSDETDFSGAIANFRNLKALISRNS
DRMALCTRAADIERCKRDGKIGMVPFFQNPKPIADRLADLEIFYELGLRVFQMTYNNLGFIGAGCCERNDPGLSNFGIEV
VSKCNELGILLDISHCGPATSWDTLKFSKAPVVASHSGAYALARAFGRNKPDDMLKAVADTGGLAGIPFFPCLVKRDPET
HVVQPSTVEDVIDHIDHAVEIMGIDHVGIASDMSSHLARTLELTRDSVLRTTRLRHPEVFGVGPTDRYDPYPAGLDSHAK
MLNLSRGLHKRGYAEGDIIKILGGNWMRVYSAVWKD

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=273, Percent_Identity=29.3040293040293, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4758190, Length=273, Percent_Identity=29.3040293040293, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI11641269, Length=247, Percent_Identity=27.5303643724696, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI193211608, Length=245, Percent_Identity=25.3061224489796, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362638, Length=290, Percent_Identity=32.0689655172414, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281362636, Length=290, Percent_Identity=32.0689655172414, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI221475880, Length=290, Percent_Identity=27.9310344827586, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI161083233, Length=202, Percent_Identity=32.1782178217822, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 39243; Mature: 39112

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYYELSADEDLNILRLHEKAIVFDGAFPMLGFYKAPEEEIDAFLKGGVTGGNATLSSDE
CCEEECCCCCCCCEEEEECEEEEECCCCHHHHCCCCCHHHHHHHHHCCCCCCCCEECCCC
TDFSGAIANFRNLKALISRNSDRMALCTRAADIERCKRDGKIGMVPFFQNPKPIADRLAD
CCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LEIFYELGLRVFQMTYNNLGFIGAGCCERNDPGLSNFGIEVVSKCNELGILLDISHCGPA
HHHHHHHHHHHEEHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCC
TSWDTLKFSKAPVVASHSGAYALARAFGRNKPDDMLKAVADTGGLAGIPFFPCLVKRDPE
CCCCCEEECCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
THVVQPSTVEDVIDHIDHAVEIMGIDHVGIASDMSSHLARTLELTRDSVLRTTRLRHPEV
CCEECCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FGVGPTDRYDPYPAGLDSHAKMLNLSRGLHKRGYAEGDIIKILGGNWMRVYSAVWKD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCC
>Mature Secondary Structure 
SYYELSADEDLNILRLHEKAIVFDGAFPMLGFYKAPEEEIDAFLKGGVTGGNATLSSDE
CEEECCCCCCCCEEEEECEEEEECCCCHHHHCCCCCHHHHHHHHHCCCCCCCCEECCCC
TDFSGAIANFRNLKALISRNSDRMALCTRAADIERCKRDGKIGMVPFFQNPKPIADRLAD
CCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LEIFYELGLRVFQMTYNNLGFIGAGCCERNDPGLSNFGIEVVSKCNELGILLDISHCGPA
HHHHHHHHHHHEEHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCC
TSWDTLKFSKAPVVASHSGAYALARAFGRNKPDDMLKAVADTGGLAGIPFFPCLVKRDPE
CCCCCEEECCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
THVVQPSTVEDVIDHIDHAVEIMGIDHVGIASDMSSHLARTLELTRDSVLRTTRLRHPEV
CCEECCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FGVGPTDRYDPYPAGLDSHAKMLNLSRGLHKRGYAEGDIIKILGGNWMRVYSAVWKD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]