Click here to switch to the map view.

The map label for this gene is abgR [H]

Identifier: 110634198

GI number: 110634198

Start: 1984874

End: 1985818

Strand: Reverse

Name: abgR [H]

Synonym: Meso_1848

Alternate gene names: 110634198

Gene position: 1985818-1984874 (Counterclockwise)

Preceding gene: 110634199

Following gene: 110634197

Centisome position: 45.0

GC content: 61.48

Gene sequence:

>945_bases
ATGAACCTCAGAAGCATCCCCGTGGCGCAGCTCTTGGAGTTGCTGGCGGTGGTCCGGTGTGGCAGCATCAATCGGGCCGC
TCAGGAGCTGAACACCACCCAGCCTACGCTGACCAGAAGCATCAAAAGGCTGGAGGACCGGCTGAGGGTGCCTCTGCTTC
AACGAACCGCACATGGCGTGACGCCATCCGAATACACCAAAGCGATGCTCCCTTTCCTCCAGAGCATCGAGAGCGACTTC
AGGAAAGCCTTGGCGGAAATTGAGGCTGCCACCGGAGCCGGCGCGGGCAAGATCTGCATCGGCTCGACGGCCATGGTGGC
AAACAAGATCGTCCCGCAGGTGCTTGCCCGGTTTGTCCCGCGCTGGCCGCATCTGACCATCGAATTCGTCGAGGACCGCA
AACCCGCCCTGCTCGAAGGATTGCGGAGCGGCAAATACGATTTCGTCATGGCCCTTATGAGCCCCGAGGAGCAGGCGCGG
GACATCCTGCAGCAGGAACTCTTCACCGACACGCTCGTGGTCATTGCCCGCCCGGGCCATCCTCTTACCAAGCTTTCGTC
CCTGTCCGTGCGCGATATCGTCCAGTGCAAATGGATCCTGCCTACGGAGGGGCTCGACCTGCGCAGCCGCCTGGAGAATT
TCTTCCGCAACGAAGGACACGACGTGCCGGCGTTCCCGGTCGAAACGACGCTCTTCACAGCGATCGTCGCTCTTGTGAAG
AGCACCGACCGGATCTCCGCGATTCCATCCGTGGTCGTAAGGGACGAACTGCTCAGCGGCGAGCTTGTAGCGCTGCGCGG
CCCTTGGAACTTCATCCACCGCTCGTTCAGCGCCTATTTCAGGCGCGGGCATACGCTCTCTCCTTCCGCCCGCGAGCTGT
TCCGGGAAACCCGCCGATATATTACCGAACTCGGCGTCAACGTTCAGAAGGCGGCTGCCGAATAG

Upstream 100 bases:

>100_bases
CCTCGATCAAGGTGCGCCTGGGAGGCCTGCCGATGAAAGGCGCGCTCCGCGCGAAATTGTGGTTTCATTGGTTTCCTTGC
CAGTATGAGGAGGCGAACCA

Downstream 100 bases:

>100_bases
GTCAGAGGGCACTTCTGCTGCGCTAATGGAGGATGGCTATACACTTCAGGCATAACCCCGTGCCTCAATGCATTGGCGAA
ATGCTCCAGCTTGGAGTGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNLRSIPVAQLLELLAVVRCGSINRAAQELNTTQPTLTRSIKRLEDRLRVPLLQRTAHGVTPSEYTKAMLPFLQSIESDF
RKALAEIEAATGAGAGKICIGSTAMVANKIVPQVLARFVPRWPHLTIEFVEDRKPALLEGLRSGKYDFVMALMSPEEQAR
DILQQELFTDTLVVIARPGHPLTKLSSLSVRDIVQCKWILPTEGLDLRSRLENFFRNEGHDVPAFPVETTLFTAIVALVK
STDRISAIPSVVVRDELLSGELVALRGPWNFIHRSFSAYFRRGHTLSPSARELFRETRRYITELGVNVQKAAAE

Sequences:

>Translated_314_residues
MNLRSIPVAQLLELLAVVRCGSINRAAQELNTTQPTLTRSIKRLEDRLRVPLLQRTAHGVTPSEYTKAMLPFLQSIESDF
RKALAEIEAATGAGAGKICIGSTAMVANKIVPQVLARFVPRWPHLTIEFVEDRKPALLEGLRSGKYDFVMALMSPEEQAR
DILQQELFTDTLVVIARPGHPLTKLSSLSVRDIVQCKWILPTEGLDLRSRLENFFRNEGHDVPAFPVETTLFTAIVALVK
STDRISAIPSVVVRDELLSGELVALRGPWNFIHRSFSAYFRRGHTLSPSARELFRETRRYITELGVNVQKAAAE
>Mature_314_residues
MNLRSIPVAQLLELLAVVRCGSINRAAQELNTTQPTLTRSIKRLEDRLRVPLLQRTAHGVTPSEYTKAMLPFLQSIESDF
RKALAEIEAATGAGAGKICIGSTAMVANKIVPQVLARFVPRWPHLTIEFVEDRKPALLEGLRSGKYDFVMALMSPEEQAR
DILQQELFTDTLVVIARPGHPLTKLSSLSVRDIVQCKWILPTEGLDLRSRLENFFRNEGHDVPAFPVETTLFTAIVALVK
STDRISAIPSVVVRDELLSGELVALRGPWNFIHRSFSAYFRRGHTLSPSARELFRETRRYITELGVNVQKAAAE

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=260, Percent_Identity=26.5384615384615, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789506, Length=233, Percent_Identity=24.8927038626609, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081904, Length=292, Percent_Identity=22.9452054794521, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693105, Length=274, Percent_Identity=24.8175182481752, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=259, Percent_Identity=26.2548262548263, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789204, Length=266, Percent_Identity=25.187969924812, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=21.900826446281, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=281, Percent_Identity=22.0640569395018, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=292, Percent_Identity=23.972602739726, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=216, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35121; Mature: 35121

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRSIPVAQLLELLAVVRCGSINRAAQELNTTQPTLTRSIKRLEDRLRVPLLQRTAHGV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCC
TPSEYTKAMLPFLQSIESDFRKALAEIEAATGAGAGKICIGSTAMVANKIVPQVLARFVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
RWPHLTIEFVEDRKPALLEGLRSGKYDFVMALMSPEEQARDILQQELFTDTLVVIARPGH
CCCCEEEEECCCCCHHHHHHHHCCCHHEEHHHHCCHHHHHHHHHHHHHHHHEEEEECCCC
PLTKLSSLSVRDIVQCKWILPTEGLDLRSRLENFFRNEGHDVPAFPVETTLFTAIVALVK
CHHHHHCCCHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
STDRISAIPSVVVRDELLSGELVALRGPWNFIHRSFSAYFRRGHTLSPSARELFRETRRY
CCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ITELGVNVQKAAAE
HHHHCCCHHHHCCC
>Mature Secondary Structure
MNLRSIPVAQLLELLAVVRCGSINRAAQELNTTQPTLTRSIKRLEDRLRVPLLQRTAHGV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCC
TPSEYTKAMLPFLQSIESDFRKALAEIEAATGAGAGKICIGSTAMVANKIVPQVLARFVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
RWPHLTIEFVEDRKPALLEGLRSGKYDFVMALMSPEEQARDILQQELFTDTLVVIARPGH
CCCCEEEEECCCCCHHHHHHHHCCCHHEEHHHHCCHHHHHHHHHHHHHHHHEEEEECCCC
PLTKLSSLSVRDIVQCKWILPTEGLDLRSRLENFFRNEGHDVPAFPVETTLFTAIVALVK
CHHHHHCCCHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
STDRISAIPSVVVRDELLSGELVALRGPWNFIHRSFSAYFRRGHTLSPSARELFRETRRY
CCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ITELGVNVQKAAAE
HHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]