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The map label for this gene is crtB [H]

Identifier: 110634145

GI number: 110634145

Start: 1920192

End: 1921016

Strand: Reverse

Name: crtB [H]

Synonym: Meso_1794

Alternate gene names: 110634145

Gene position: 1921016-1920192 (Counterclockwise)

Preceding gene: 110634146

Following gene: 110634144

Centisome position: 43.54

GC content: 63.27

Gene sequence:

>825_bases
ATGGCCGTACGCGTTCGCCAAGCCGATCCGGACCGCTATCTTGCCACACTCTATGCGCCCGTTGAAAAGCGTGGCGCGCT
TTTCGCTCTTTATGCCTTCAATGCCGAGATCGCGGCGGTTCGTGAACGGGTGAGTCAGCCGCTCCCCGGCGAAATTCGCC
TGCAATGGTGGCAGGATGCGCTGGAAAACCCGGAAGATCCGGCGGCTGCCGCGGGCCACCCCGTCGCGGCAGCCCTCCTC
GATACGATCCGCGCCCACCATTTGCCTGTCGAGACGTTCCGAAACATGATCGAAGCACGGGTTTTTGACCTCTATGACGA
TCCGATGCCAAGCCGTACCGATCTGGAAGGCTATTGTGGCGAGACTGCCTCGGCGCTGATCCAGCTTTCGGCCCTCGTCC
TTGATCCTGAGGCGGCGGGCAGCACCGCTGCGCTGGCCGGTCATGCCGGCTGCGCCCAGGCAATCGCAGGGCTTCTGAGA
TTGTTGCCGATCCATCGGCGCCGGGGGCAATGCTATATTCCCCACGACCTTCTGCAGGCGGCTGGCACCACGCGCGACGG
CATAATATCCGGCGAGGACCGCGCCGGTTCTGCCCGGGCCATTGCCGCGATGGTGGCGCTCGCGCGGCATCATCTCAGCG
CATTTACAAACGGGGCGGGCGAGCTGCCGGCCTCCTTGCGTCCTGCCTACCTGCCGCTGGCGCTCACCAAGGCCTATCTG
GATCCTATCGAATCGGGGGCGGTTGATCCGTTGTCTGAAAGTGCTTCACTTTCTGTTTTGCGCCGGCACTGGCTTCTTCT
GAAGCATGCGATGCGCGGCTGGTAG

Upstream 100 bases:

>100_bases
GGGGCTGCCGCCCGCACCTTCAATGTACTGCTGGCGGAAGAGAGGGCGGTAGCGGCGGCGCTGATCGCCGTCGACTAAGA
TGACACCCTCCGGCGCCGAA

Downstream 100 bases:

>100_bases
AGCAACCAGCGGAGTTTAAGCCGGCCTCTTGTGCAAATCTGGCGTGCATAGACTGCAATTTCGCCACTCTTCCTTTGCTC
CAATGCGGCGTTTTCATTAC

Product: squalene/phytoene synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MAVRVRQADPDRYLATLYAPVEKRGALFALYAFNAEIAAVRERVSQPLPGEIRLQWWQDALENPEDPAAAAGHPVAAALL
DTIRAHHLPVETFRNMIEARVFDLYDDPMPSRTDLEGYCGETASALIQLSALVLDPEAAGSTAALAGHAGCAQAIAGLLR
LLPIHRRRGQCYIPHDLLQAAGTTRDGIISGEDRAGSARAIAAMVALARHHLSAFTNGAGELPASLRPAYLPLALTKAYL
DPIESGAVDPLSESASLSVLRRHWLLLKHAMRGW

Sequences:

>Translated_274_residues
MAVRVRQADPDRYLATLYAPVEKRGALFALYAFNAEIAAVRERVSQPLPGEIRLQWWQDALENPEDPAAAAGHPVAAALL
DTIRAHHLPVETFRNMIEARVFDLYDDPMPSRTDLEGYCGETASALIQLSALVLDPEAAGSTAALAGHAGCAQAIAGLLR
LLPIHRRRGQCYIPHDLLQAAGTTRDGIISGEDRAGSARAIAAMVALARHHLSAFTNGAGELPASLRPAYLPLALTKAYL
DPIESGAVDPLSESASLSVLRRHWLLLKHAMRGW
>Mature_273_residues
AVRVRQADPDRYLATLYAPVEKRGALFALYAFNAEIAAVRERVSQPLPGEIRLQWWQDALENPEDPAAAAGHPVAAALLD
TIRAHHLPVETFRNMIEARVFDLYDDPMPSRTDLEGYCGETASALIQLSALVLDPEAAGSTAALAGHAGCAQAIAGLLRL
LPIHRRRGQCYIPHDLLQAAGTTRDGIISGEDRAGSARAIAAMVALARHHLSAFTNGAGELPASLRPAYLPLALTKAYLD
PIESGAVDPLSESASLSVLRRHWLLLKHAMRGW

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

Organism=Homo sapiens, GI124517691, Length=247, Percent_Identity=27.5303643724696, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24641447, Length=247, Percent_Identity=30.3643724696356, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 29556; Mature: 29425

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVRQADPDRYLATLYAPVEKRGALFALYAFNAEIAAVRERVSQPLPGEIRLQWWQDA
CCEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHH
LENPEDPAAAAGHPVAAALLDTIRAHHLPVETFRNMIEARVFDLYDDPMPSRTDLEGYCG
HCCCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCC
ETASALIQLSALVLDPEAAGSTAALAGHAGCAQAIAGLLRLLPIHRRRGQCYIPHDLLQA
HHHHHHHHHHHHEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
AGTTRDGIISGEDRAGSARAIAAMVALARHHLSAFTNGAGELPASLRPAYLPLALTKAYL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
DPIESGAVDPLSESASLSVLRRHWLLLKHAMRGW
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVRVRQADPDRYLATLYAPVEKRGALFALYAFNAEIAAVRERVSQPLPGEIRLQWWQDA
CEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHH
LENPEDPAAAAGHPVAAALLDTIRAHHLPVETFRNMIEARVFDLYDDPMPSRTDLEGYCG
HCCCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCC
ETASALIQLSALVLDPEAAGSTAALAGHAGCAQAIAGLLRLLPIHRRRGQCYIPHDLLQA
HHHHHHHHHHHHEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
AGTTRDGIISGEDRAGSARAIAAMVALARHHLSAFTNGAGELPASLRPAYLPLALTKAYL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
DPIESGAVDPLSESASLSVLRRHWLLLKHAMRGW
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537409 [H]