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The map label for this gene is sufC [H]

Identifier: 110634131

GI number: 110634131

Start: 1901292

End: 1902047

Strand: Reverse

Name: sufC [H]

Synonym: Meso_1780

Alternate gene names: 110634131

Gene position: 1902047-1901292 (Counterclockwise)

Preceding gene: 110634132

Following gene: 110634130

Centisome position: 43.11

GC content: 60.85

Gene sequence:

>756_bases
ATGCTTGAGATCAAGAACCTGCATGCCCGCATCGCCGAAGACGGCACAGAGATCCTGCGCGGGGTGAACCTTGCCGTGAA
ACCGGGCGAAGTGGCTGCCATCATGGGCCCGAACGGCTCCGGCAAATCCACGCTTTCCTATGTGCTCGCCGGCCGGGACG
ACTATGAGGTGACCGAGGGCGATATTCTCTTCAAGGGGCAATCCATTCTGGAGATGGACCCGGCCGAGCGCGCCGCCACG
GGCATTTTCCTCGCTTTCCAATATCCGATGGAGATACCGGGCGTGGCCACCATGGAGTTCCTGAAGGTGGCCATGAATGC
CCAGCGCAGGGCGCGCGGCGAGGAGGAGCTGAAGATCCCCGAGCTTCTGAAGCGCGTGCGCACGGCCGCGCAAGAGCTCG
ACATGGACATGAACATGCTGAAGCGCCCGCTCAATGTAGGTTTTTCCGGCGGTGAGAAGAAGCGCGCGGAGATCCTGCAG
ATGAAGCTCCTGGAGCCTTCTCTCTGCGTGCTGGACGAGACCGATTCAGGGCTCGACATCGATGCGCTCAAGATTGTGGC
AGAAGGCGTCAACGCGCTGCGCTCGCCCGATCGCACCATCGTCGTGATCACGCACTATCAGCGCCTGCTCGACTATATCG
TGCCCGATTCCGTGCATGTGCTTTATAAGGGCCAGGTTGTGAAGTCCGGTGAAAAGGAATTGGCGCAGGAGCTGGAGAAG
AACGGCTATGCCGGGCTGATCGGCGAGGCGGCCTGA

Upstream 100 bases:

>100_bases
ATTGCCGATGGAGTTCGCCGTCGAGGCGCAGAAGCTGATCGGCATTTCGCTTGAAGGTTCGGTCGGCTGAGTGGGCCGCA
GACAGTTTGGGATAGGAATT

Downstream 100 bases:

>100_bases
GGGCAGAGATGATGAATTTGCAGGTTCAGGTAAGACATACCGCCGCCGAGGAGGCGCTGCTTTCGGCCTATTCGGAGCGC
GCCGCCAGCCTTCCCGGAGA

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIKNLHARIAEDGTEILRGVNLAVKPGEVAAIMGPNGSGKSTLSYVLAGRDDYEVTEGDILFKGQSILEMDPAERAAT
GIFLAFQYPMEIPGVATMEFLKVAMNAQRRARGEEELKIPELLKRVRTAAQELDMDMNMLKRPLNVGFSGGEKKRAEILQ
MKLLEPSLCVLDETDSGLDIDALKIVAEGVNALRSPDRTIVVITHYQRLLDYIVPDSVHVLYKGQVVKSGEKELAQELEK
NGYAGLIGEAA

Sequences:

>Translated_251_residues
MLEIKNLHARIAEDGTEILRGVNLAVKPGEVAAIMGPNGSGKSTLSYVLAGRDDYEVTEGDILFKGQSILEMDPAERAAT
GIFLAFQYPMEIPGVATMEFLKVAMNAQRRARGEEELKIPELLKRVRTAAQELDMDMNMLKRPLNVGFSGGEKKRAEILQ
MKLLEPSLCVLDETDSGLDIDALKIVAEGVNALRSPDRTIVVITHYQRLLDYIVPDSVHVLYKGQVVKSGEKELAQELEK
NGYAGLIGEAA
>Mature_251_residues
MLEIKNLHARIAEDGTEILRGVNLAVKPGEVAAIMGPNGSGKSTLSYVLAGRDDYEVTEGDILFKGQSILEMDPAERAAT
GIFLAFQYPMEIPGVATMEFLKVAMNAQRRARGEEELKIPELLKRVRTAAQELDMDMNMLKRPLNVGFSGGEKKRAEILQ
MKLLEPSLCVLDETDSGLDIDALKIVAEGVNALRSPDRTIVVITHYQRLLDYIVPDSVHVLYKGQVVKSGEKELAQELEK
NGYAGLIGEAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=235, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI156105685, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI62526033, Length=233, Percent_Identity=30.4721030042918, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI42741659, Length=211, Percent_Identity=28.436018957346, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI255708477, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787972, Length=246, Percent_Identity=57.7235772357724, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI87082267, Length=169, Percent_Identity=32.5443786982249, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789864, Length=241, Percent_Identity=25.7261410788382, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=244, Percent_Identity=27.0491803278689, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789891, Length=224, Percent_Identity=31.25, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=28.436018957346, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788225, Length=235, Percent_Identity=27.2340425531915, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790525, Length=215, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790467, Length=232, Percent_Identity=28.8793103448276, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786703, Length=218, Percent_Identity=29.8165137614679, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787500, Length=218, Percent_Identity=28.4403669724771, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87081709, Length=252, Percent_Identity=23.015873015873, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789672, Length=216, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=28.2296650717703, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=213, Percent_Identity=27.2300469483568, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994883, Length=249, Percent_Identity=27.3092369477912, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787758, Length=252, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788761, Length=208, Percent_Identity=25.9615384615385, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI87081791, Length=250, Percent_Identity=26.8, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1789963, Length=239, Percent_Identity=28.0334728033473, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=229, Percent_Identity=29.2576419213974, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565938, Length=224, Percent_Identity=29.9107142857143, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71992290, Length=253, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=215, Percent_Identity=28.3720930232558, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=216, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=233, Percent_Identity=27.8969957081545, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=213, Percent_Identity=30.5164319248826, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=216, Percent_Identity=28.7037037037037, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=227, Percent_Identity=29.0748898678414, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=216, Percent_Identity=28.7037037037037, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=244, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319856, Length=246, Percent_Identity=29.2682926829268, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324498, Length=201, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI85816269, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580553, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85724864, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580555, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653245, Length=242, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363262, Length=236, Percent_Identity=26.6949152542373, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27539; Mature: 27539

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKNLHARIAEDGTEILRGVNLAVKPGEVAAIMGPNGSGKSTLSYVLAGRDDYEVTEG
CCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCHHHEEEEECCCCCEECCC
DILFKGQSILEMDPAERAATGIFLAFQYPMEIPGVATMEFLKVAMNAQRRARGEEELKIP
CEEECCCCCEECCCHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
ELLKRVRTAAQELDMDMNMLKRPLNVGFSGGEKKRAEILQMKLLEPSLCVLDETDSGLDI
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVAEGVNALRSPDRTIVVITHYQRLLDYIVPDSVHVLYKGQVVKSGEKELAQELEK
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEEEECEEECCCHHHHHHHHHH
NGYAGLIGEAA
CCCCCCCCCCC
>Mature Secondary Structure
MLEIKNLHARIAEDGTEILRGVNLAVKPGEVAAIMGPNGSGKSTLSYVLAGRDDYEVTEG
CCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCHHHEEEEECCCCCEECCC
DILFKGQSILEMDPAERAATGIFLAFQYPMEIPGVATMEFLKVAMNAQRRARGEEELKIP
CEEECCCCCEECCCHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
ELLKRVRTAAQELDMDMNMLKRPLNVGFSGGEKKRAEILQMKLLEPSLCVLDETDSGLDI
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVAEGVNALRSPDRTIVVITHYQRLLDYIVPDSVHVLYKGQVVKSGEKELAQELEK
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEEEECEEECCCHHHHHHHHHH
NGYAGLIGEAA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]