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The map label for this gene is ycfH [H]

Identifier: 110633936

GI number: 110633936

Start: 1705297

End: 1706091

Strand: Direct

Name: ycfH [H]

Synonym: Meso_1584

Alternate gene names: 110633936

Gene position: 1705297-1706091 (Clockwise)

Preceding gene: 110633935

Following gene: 110633937

Centisome position: 38.65

GC content: 61.13

Gene sequence:

>795_bases
ATGCTGGTCGACAGCCATTGCCACCTGGATTTCCCGGATTTCGAAGCGGAGCGGGACCAGATCATCGCCCGCGCTGGCGA
TGCCGGCGTGGGCCTGATGGTCACCATTTCCACCCGCGTCAGGAACTTCGACTCGATCCGCGCGATCGCGGGGCAGTACG
ACAATGTCTATTGCACCGTGGGCACGCATCCGCACAACGCTGCGGAGGAGGAGGATGTCACCGCGGAGGATCTGATCCGT
CTTTCCGAACATCCCAAAGTGGTCGGAATTGGCGAAGCGGGTCTCGACTATTTCTATGACAAATCTCCGCGCGATCAGCA
GGCGAAGGGGTTGCGCACGCATATCGAGGCGGCGCGCCGCACCGGGCTTCCGCTCGTCATCCACGCCCGCGATGCCGATG
ACGACATGGCCGCGATCCTTGGCGAGGAGACAGGGAAGGGCGCTTTTCCCTTCATCCTCCACTGCTTCTCGTCCGGTCCA
GCGCTGGCCTGCACCGGTGTGGAGCTTGGCGGATATATCTCCTTCTCCGGGATCCTGACGTTCAAGAAGTCCGAGGCGCT
GCGGGAGATTGCGGCTTTCGTTCCCCGCGAGAGGCTGCTTGTCGAGACTGACGCGCCTTACCTTGCTCCAGTACCGCATC
GTGGTAAGCGCAATGAGCCTGCTTTCGTGGCGCATACAGCCGCGGTTCTTGCCGAGACAATCGGACTATCGCCCGAGGAA
GTAGCTCATCTTACGACCGGAAACTTCTTCCGCCTGTTTACCAAAGTTCCGCCCTCAGGGCAGAAAGGCGCCTGA

Upstream 100 bases:

>100_bases
CGATGTAGGAGAGACGGCGATGCTCGCGCCGGGAACGCCGCTGCCGGCGCCTCAACCGGTTTTCCCGCGTTATGTGGAGC
AGGAAGGGCAGGAGGGCTGA

Downstream 100 bases:

>100_bases
AGGTGGGGGACCGCATTCGCCTGACGATCCTGGGTTGCGGCTCATCCCCCGGCGTCCCGCGCATCATTGGCGACTGGGGT
GCTTGCGACCCGAGCAACCC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLVDSHCHLDFPDFEAERDQIIARAGDAGVGLMVTISTRVRNFDSIRAIAGQYDNVYCTVGTHPHNAAEEEDVTAEDLIR
LSEHPKVVGIGEAGLDYFYDKSPRDQQAKGLRTHIEAARRTGLPLVIHARDADDDMAAILGEETGKGAFPFILHCFSSGP
ALACTGVELGGYISFSGILTFKKSEALREIAAFVPRERLLVETDAPYLAPVPHRGKRNEPAFVAHTAAVLAETIGLSPEE
VAHLTTGNFFRLFTKVPPSGQKGA

Sequences:

>Translated_264_residues
MLVDSHCHLDFPDFEAERDQIIARAGDAGVGLMVTISTRVRNFDSIRAIAGQYDNVYCTVGTHPHNAAEEEDVTAEDLIR
LSEHPKVVGIGEAGLDYFYDKSPRDQQAKGLRTHIEAARRTGLPLVIHARDADDDMAAILGEETGKGAFPFILHCFSSGP
ALACTGVELGGYISFSGILTFKKSEALREIAAFVPRERLLVETDAPYLAPVPHRGKRNEPAFVAHTAAVLAETIGLSPEE
VAHLTTGNFFRLFTKVPPSGQKGA
>Mature_264_residues
MLVDSHCHLDFPDFEAERDQIIARAGDAGVGLMVTISTRVRNFDSIRAIAGQYDNVYCTVGTHPHNAAEEEDVTAEDLIR
LSEHPKVVGIGEAGLDYFYDKSPRDQQAKGLRTHIEAARRTGLPLVIHARDADDDMAAILGEETGKGAFPFILHCFSSGP
ALACTGVELGGYISFSGILTFKKSEALREIAAFVPRERLLVETDAPYLAPVPHRGKRNEPAFVAHTAAVLAETIGLSPEE
VAHLTTGNFFRLFTKVPPSGQKGA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=274, Percent_Identity=32.1167883211679, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI226061853, Length=280, Percent_Identity=32.5, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI110349734, Length=273, Percent_Identity=31.5018315018315, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=30.8880308880309, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI14042943, Length=264, Percent_Identity=26.1363636363636, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI225903424, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=31.6239316239316, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI225903439, Length=228, Percent_Identity=27.6315789473684, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=44.5736434108527, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=33.2046332046332, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=32.4324324324324, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=31.3167259786477, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=26.3358778625954, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=223, Percent_Identity=30.9417040358744, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=30.0353356890459, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221330018, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24586117, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28609; Mature: 28609

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDFPDFEAERDQIIARAGDAGVGLMVTISTRVRNFDSIRAIAGQYDNVYCTV
CEECCCCCCCCCCCCCCHHHHEEECCCCCCEEEEEEEHHHCCHHHHHHHHCCCCCEEEEE
GTHPHNAAEEEDVTAEDLIRLSEHPKVVGIGEAGLDYFYDKSPRDQQAKGLRTHIEAARR
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
TGLPLVIHARDADDDMAAILGEETGKGAFPFILHCFSSGPALACTGVELGGYISFSGILT
CCCEEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECEEECCEEEEEEEEE
FKKSEALREIAAFVPRERLLVETDAPYLAPVPHRGKRNEPAFVAHTAAVLAETIGLSPEE
EHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
VAHLTTGNFFRLFTKVPPSGQKGA
HHEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MLVDSHCHLDFPDFEAERDQIIARAGDAGVGLMVTISTRVRNFDSIRAIAGQYDNVYCTV
CEECCCCCCCCCCCCCCHHHHEEECCCCCCEEEEEEEHHHCCHHHHHHHHCCCCCEEEEE
GTHPHNAAEEEDVTAEDLIRLSEHPKVVGIGEAGLDYFYDKSPRDQQAKGLRTHIEAARR
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
TGLPLVIHARDADDDMAAILGEETGKGAFPFILHCFSSGPALACTGVELGGYISFSGILT
CCCEEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECEEECCEEEEEEEEE
FKKSEALREIAAFVPRERLLVETDAPYLAPVPHRGKRNEPAFVAHTAAVLAETIGLSPEE
EHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
VAHLTTGNFFRLFTKVPPSGQKGA
HHEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]