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The map label for this gene is lipB [H]

Identifier: 110633937

GI number: 110633937

Start: 1706094

End: 1706912

Strand: Direct

Name: lipB [H]

Synonym: Meso_1585

Alternate gene names: 110633937

Gene position: 1706094-1706912 (Clockwise)

Preceding gene: 110633936

Following gene: 110633938

Centisome position: 38.67

GC content: 61.17

Gene sequence:

>819_bases
GTGGGGGACCGCATTCGCCTGACGATCCTGGGTTGCGGCTCATCCCCCGGCGTCCCGCGCATCATTGGCGACTGGGGTGC
TTGCGACCCGAGCAACCCGAAGAACCGCCGCCTGCGCGCTGCCGCCCTGGTCGAACGGATAAGGCCCGATGGCCGTGTCA
CGCGCGTGGTGATCGATACTGGCCCCGACTTCCGCACACAGATGATCGCAGCGAAGGCGACGAGCCTTGACGCCGTCGTC
TACACGCATCCCCATGCAGACCACATCCATGGGATTGACGATCTGCGCAGCTATGTCCTGGCGCAGCGCCAACTCATGGA
CATTTACGCAGACGAGCAGACGCTGCAGAGGCTCAAGGACGCTTTTGATTATTGCTTTGAGACGCTGCCCGGCAGCAACT
ATCCGCCCATAGTCGTTCCTCATCTCATTCGTCACGAGCAGACCTTCACAGTTTCGGGCGAGGGCGGTCCGCTAACCTTC
ACGCCATTGCCCCAGATCCATGGCGATATCCGCTCGCTCGGCTTTCGCGTCGGCAATATCGCCTATTGCTCGGATGTCAG
CGACTTTCCGCCCGAAACTCTGCCCCTGTTGCAGGGCCTGGAGATATTGGTGCTGGACGCGCTGCAATACAGGCCACATC
CCAGCCATTTGTCTCTAGGTGAGGCGCTGCAATGGATCGGGCGGCTGGCGCCCCGCCGCGCCATTCTCACGCATATGCAC
ACGCCTCTCGATTATGAGGCGGTCCGGCAGGAGACGCCAGACAATGTCGATCCGGCCTATGATGGGATGACGCTTGAAGT
TGAGGCGCTAGACCTTTGA

Upstream 100 bases:

>100_bases
CAATCGGACTATCGCCCGAGGAAGTAGCTCATCTTACGACCGGAAACTTCTTCCGCCTGTTTACCAAAGTTCCGCCCTCA
GGGCAGAAAGGCGCCTGAAG

Downstream 100 bases:

>100_bases
TTTTACGGAAAGGTTGACGCAAGATAAGCAGCATCGCCGCACCGGATGAGGGGTAGGCGCGGTCATGCAGGGCAGCACGG
CGGGCCGGTAAGGTTGCTGC

Product: beta-lactamase-like

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MGDRIRLTILGCGSSPGVPRIIGDWGACDPSNPKNRRLRAAALVERIRPDGRVTRVVIDTGPDFRTQMIAAKATSLDAVV
YTHPHADHIHGIDDLRSYVLAQRQLMDIYADEQTLQRLKDAFDYCFETLPGSNYPPIVVPHLIRHEQTFTVSGEGGPLTF
TPLPQIHGDIRSLGFRVGNIAYCSDVSDFPPETLPLLQGLEILVLDALQYRPHPSHLSLGEALQWIGRLAPRRAILTHMH
TPLDYEAVRQETPDNVDPAYDGMTLEVEALDL

Sequences:

>Translated_272_residues
MGDRIRLTILGCGSSPGVPRIIGDWGACDPSNPKNRRLRAAALVERIRPDGRVTRVVIDTGPDFRTQMIAAKATSLDAVV
YTHPHADHIHGIDDLRSYVLAQRQLMDIYADEQTLQRLKDAFDYCFETLPGSNYPPIVVPHLIRHEQTFTVSGEGGPLTF
TPLPQIHGDIRSLGFRVGNIAYCSDVSDFPPETLPLLQGLEILVLDALQYRPHPSHLSLGEALQWIGRLAPRRAILTHMH
TPLDYEAVRQETPDNVDPAYDGMTLEVEALDL
>Mature_271_residues
GDRIRLTILGCGSSPGVPRIIGDWGACDPSNPKNRRLRAAALVERIRPDGRVTRVVIDTGPDFRTQMIAAKATSLDAVVY
THPHADHIHGIDDLRSYVLAQRQLMDIYADEQTLQRLKDAFDYCFETLPGSNYPPIVVPHLIRHEQTFTVSGEGGPLTFT
PLPQIHGDIRSLGFRVGNIAYCSDVSDFPPETLPLLQGLEILVLDALQYRPHPSHLSLGEALQWIGRLAPRRAILTHMHT
PLDYEAVRQETPDNVDPAYDGMTLEVEALDL

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 30254; Mature: 30123

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRIRLTILGCGSSPGVPRIIGDWGACDPSNPKNRRLRAAALVERIRPDGRVTRVVIDT
CCCEEEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEC
GPDFRTQMIAAKATSLDAVVYTHPHADHIHGIDDLRSYVLAQRQLMDIYADEQTLQRLKD
CCCHHHHHHHHHHCCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AFDYCFETLPGSNYPPIVVPHLIRHEQTFTVSGEGGPLTFTPLPQIHGDIRSLGFRVGNI
HHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCE
AYCSDVSDFPPETLPLLQGLEILVLDALQYRPHPSHLSLGEALQWIGRLAPRRAILTHMH
EEECCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHC
TPLDYEAVRQETPDNVDPAYDGMTLEVEALDL
CCCCHHHHHHCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
GDRIRLTILGCGSSPGVPRIIGDWGACDPSNPKNRRLRAAALVERIRPDGRVTRVVIDT
CCEEEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEC
GPDFRTQMIAAKATSLDAVVYTHPHADHIHGIDDLRSYVLAQRQLMDIYADEQTLQRLKD
CCCHHHHHHHHHHCCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AFDYCFETLPGSNYPPIVVPHLIRHEQTFTVSGEGGPLTFTPLPQIHGDIRSLGFRVGNI
HHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCE
AYCSDVSDFPPETLPLLQGLEILVLDALQYRPHPSHLSLGEALQWIGRLAPRRAILTHMH
EEECCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHC
TPLDYEAVRQETPDNVDPAYDGMTLEVEALDL
CCCCHHHHHHCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]