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The map label for this gene is cobT [H]

Identifier: 110633905

GI number: 110633905

Start: 1669714

End: 1670685

Strand: Direct

Name: cobT [H]

Synonym: Meso_1552

Alternate gene names: 110633905

Gene position: 1669714-1670685 (Clockwise)

Preceding gene: 110633902

Following gene: 110633907

Centisome position: 37.84

GC content: 64.4

Gene sequence:

>972_bases
ATGACGAACGGCTTGCCCTTCGATGATATCCGTAACTTGATTGCCGGACTTCCTGCCATGGACCAGACGGCAGCATCGCG
AGTGCAAGCCGATCTGGCGGCGGACGGGCACGAGCTGGGGCAGGTGCGGGATGTCGCCCAATGGTTTGCAGCCGCTACCG
GTCGCGCCCCCGCGCGCGTATCGCGCCCTATGGTAGCGCTTTTCGCAGCGACGCACGCAGTGTCTGGAAAAAGAGGCATG
GCCGATCCGATAGGCGAAGCGCAATCCCGCGTGGAGGCGATCGCGGCGGGCGCCGCGCCCGTAAGCCAGCTTTGCGCCGA
CTACAATCTCGGGCTGAATGTGTTTGACTTGGCGCTGGAGCTGCCTGTCGCAGACTTTTCAGCAGGCCCCGCGCTTGAAG
AGCGGGCCGCAGCCGCCACGATGGCTTTTGGCATGGAAGCGATCGCAGCCGGCCCCGACCTCATCTGTCTGGGCACGGTA
AACGCCGCCGGCGAGCTCTCGGCCTCGGCGCTCCTTTGCGCGGTTTTGAATCAGGATATCTCCGAATGGGCAGAGTTCGG
CGCGGACGATCTCTCACTCGTCAATCAAGCGCTGGAACTTCACCAAGATCATCTCCGCGACCCGTTGGAAGCACTGCGGC
GGCTGGGCGGCAGGGAAACCGCAGCGCTCGCCGGCGCTATTATCGCAGCGCGGGCGCAGAAGATTGCGGTGATCCTCGAT
GGACCTATCGCGACAGCGGCGGCGGCTGTTCTCTATGCTATGAATCAGAATGCGCTGGAGCACTGCCTTCTGGCAGCGGC
CCAAACGGGTGGGCATCGCAAGGCGGCGGCACTTATCGGCCTGAAACCGGTTCTTAACGTTGAAGGATTGAGCAGCGGCG
GTGTCGCGGGCGCTCTTGCCGCAGGGGTGGTCCGGGGAGCGAGTGAAATCTCGGCGCGGAGGGCGGAGGTGAACGCGCGG
CTGCGCGCCTGA

Upstream 100 bases:

>100_bases
CGCACTTGCAGATGGGGGGCGTGACGGGTCGACGCAAGCCGCGGCATTGCCACAGCCGCATCCTGCCGTTATGCCCGGCG
CCAGCCCAGGAGACAATGAC

Downstream 100 bases:

>100_bases
AACTTCAGCCAACGGCACGCTTTTTTTGGCGGACTGGCGGCGCGACGGCTTCCTCGACCACACGACTTCGTGGAAAGATC
ACAGTTGCGACGGTTCCTTC

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTNGLPFDDIRNLIAGLPAMDQTAASRVQADLAADGHELGQVRDVAQWFAAATGRAPARVSRPMVALFAATHAVSGKRGM
ADPIGEAQSRVEAIAAGAAPVSQLCADYNLGLNVFDLALELPVADFSAGPALEERAAAATMAFGMEAIAAGPDLICLGTV
NAAGELSASALLCAVLNQDISEWAEFGADDLSLVNQALELHQDHLRDPLEALRRLGGRETAALAGAIIAARAQKIAVILD
GPIATAAAAVLYAMNQNALEHCLLAAAQTGGHRKAAALIGLKPVLNVEGLSSGGVAGALAAGVVRGASEISARRAEVNAR
LRA

Sequences:

>Translated_323_residues
MTNGLPFDDIRNLIAGLPAMDQTAASRVQADLAADGHELGQVRDVAQWFAAATGRAPARVSRPMVALFAATHAVSGKRGM
ADPIGEAQSRVEAIAAGAAPVSQLCADYNLGLNVFDLALELPVADFSAGPALEERAAAATMAFGMEAIAAGPDLICLGTV
NAAGELSASALLCAVLNQDISEWAEFGADDLSLVNQALELHQDHLRDPLEALRRLGGRETAALAGAIIAARAQKIAVILD
GPIATAAAAVLYAMNQNALEHCLLAAAQTGGHRKAAALIGLKPVLNVEGLSSGGVAGALAAGVVRGASEISARRAEVNAR
LRA
>Mature_322_residues
TNGLPFDDIRNLIAGLPAMDQTAASRVQADLAADGHELGQVRDVAQWFAAATGRAPARVSRPMVALFAATHAVSGKRGMA
DPIGEAQSRVEAIAAGAAPVSQLCADYNLGLNVFDLALELPVADFSAGPALEERAAAATMAFGMEAIAAGPDLICLGTVN
AAGELSASALLCAVLNQDISEWAEFGADDLSLVNQALELHQDHLRDPLEALRRLGGRETAALAGAIIAARAQKIAVILDG
PIATAAAAVLYAMNQNALEHCLLAAAQTGGHRKAAALIGLKPVLNVEGLSSGGVAGALAAGVVRGASEISARRAEVNARL
RA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=342, Percent_Identity=23.9766081871345, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 32912; Mature: 32781

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGLPFDDIRNLIAGLPAMDQTAASRVQADLAADGHELGQVRDVAQWFAAATGRAPARV
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHH
SRPMVALFAATHAVSGKRGMADPIGEAQSRVEAIAAGAAPVSQLCADYNLGLNVFDLALE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHH
LPVADFSAGPALEERAAAATMAFGMEAIAAGPDLICLGTVNAAGELSASALLCAVLNQDI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
SEWAEFGADDLSLVNQALELHQDHLRDPLEALRRLGGRETAALAGAIIAARAQKIAVILD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEC
GPIATAAAAVLYAMNQNALEHCLLAAAQTGGHRKAAALIGLKPVLNVEGLSSGGVAGALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHCCCCCCCCCCHHHHHH
AGVVRGASEISARRAEVNARLRA
HHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNGLPFDDIRNLIAGLPAMDQTAASRVQADLAADGHELGQVRDVAQWFAAATGRAPARV
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHH
SRPMVALFAATHAVSGKRGMADPIGEAQSRVEAIAAGAAPVSQLCADYNLGLNVFDLALE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHH
LPVADFSAGPALEERAAAATMAFGMEAIAAGPDLICLGTVNAAGELSASALLCAVLNQDI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
SEWAEFGADDLSLVNQALELHQDHLRDPLEALRRLGGRETAALAGAIIAARAQKIAVILD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEC
GPIATAAAAVLYAMNQNALEHCLLAAAQTGGHRKAAALIGLKPVLNVEGLSSGGVAGALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHCCCCCCCCCCHHHHHH
AGVVRGASEISARRAEVNARLRA
HHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA