Click here to switch to the map view.

The map label for this gene is yieH [H]

Identifier: 110633119

GI number: 110633119

Start: 837041

End: 837730

Strand: Reverse

Name: yieH [H]

Synonym: Meso_0762

Alternate gene names: 110633119

Gene position: 837730-837041 (Counterclockwise)

Preceding gene: 110633121

Following gene: 229259627

Centisome position: 18.99

GC content: 63.04

Gene sequence:

>690_bases
ATGCCAAAACCTGATCTCGTCATTTTCGATTGCGACGGCGTGCTCGTCGATTCCGAAATCGTCGCCGCTCGCGTCGAGGC
GGAGATGCTGCGCGAGGCGGGCTACGACATCACTGCGGACGAGATTGCGGAGCGCTATTCGGGCCTTACCTTCAAGGACA
TCATGATCCATATCGAGAAGGAGGCGCAGATGCTCCTACAGGCCTCCATGATCAAGCAAGCGGAGGCCAAGGTCGACGAG
AGGCTGCGCGCGGAGGTGAAGGCGATACCGGGCGTAGCGGAGGCGGCCGCCTCGCTTTCAGTTAAAAAATGCGTCTGCTC
CAATTCGAGCGAGGAGCGAATCGCCATCATGCTCCAGCGCACGAATCTCGCGCGCTTTTTCGAAGGTGTCATCTTCTCCT
CGCTCGCCACGCCCACCAAGCGGCCGAAGCCGGCGCCGGACGTGTTTCTCTATGCGGCGGAGCAGATGGGCGCGGAGCCC
GCGGGGACGATCGTGATCGAGGATTCCGTCCACGGGATCATGGGGGCGAGGACCGCCGGAATGCGCGTCATCGGCTTCAC
CGGCGCTTCCCACAGCCACCCCCGGCACGCTTCCATGCTGATGGAGGCGGGCGCCGAAACCACGATCAGCCGCATGGCCG
ACCTCAAGTCCACCATTGCCGCGCTTTCGGAGTGGTCGGAGGAGGGGTGA

Upstream 100 bases:

>100_bases
ACCGCCGAGATAGGGCTTCACCCCTCACCGAGCCGGTTGATCCGTATGCGCTTCGGGGTTATGGCCTCGCGTCCCCTCCA
CTTTCGTTGATGTAGAGCCA

Downstream 100 bases:

>100_bases
GGACCTGCCGTCATTGCCCTCACTTTTCTAACACCTAGCCTTCGCGTTGCTCCGGCTAACGCGTTGTAATCGCTTTCTCC
CCCATCAAGGGGGAGATAAC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPKPDLVIFDCDGVLVDSEIVAARVEAEMLREAGYDITADEIAERYSGLTFKDIMIHIEKEAQMLLQASMIKQAEAKVDE
RLRAEVKAIPGVAEAAASLSVKKCVCSNSSEERIAIMLQRTNLARFFEGVIFSSLATPTKRPKPAPDVFLYAAEQMGAEP
AGTIVIEDSVHGIMGARTAGMRVIGFTGASHSHPRHASMLMEAGAETTISRMADLKSTIAALSEWSEEG

Sequences:

>Translated_229_residues
MPKPDLVIFDCDGVLVDSEIVAARVEAEMLREAGYDITADEIAERYSGLTFKDIMIHIEKEAQMLLQASMIKQAEAKVDE
RLRAEVKAIPGVAEAAASLSVKKCVCSNSSEERIAIMLQRTNLARFFEGVIFSSLATPTKRPKPAPDVFLYAAEQMGAEP
AGTIVIEDSVHGIMGARTAGMRVIGFTGASHSHPRHASMLMEAGAETTISRMADLKSTIAALSEWSEEG
>Mature_228_residues
PKPDLVIFDCDGVLVDSEIVAARVEAEMLREAGYDITADEIAERYSGLTFKDIMIHIEKEAQMLLQASMIKQAEAKVDER
LRAEVKAIPGVAEAAASLSVKKCVCSNSSEERIAIMLQRTNLARFFEGVIFSSLATPTKRPKPAPDVFLYAAEQMGAEPA
GTIVIEDSVHGIMGARTAGMRVIGFTGASHSHPRHASMLMEAGAETTISRMADLKSTIAALSEWSEEG

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=197, Percent_Identity=28.9340101522843, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789046, Length=181, Percent_Identity=31.4917127071823, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788021, Length=182, Percent_Identity=29.1208791208791, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20129151, Length=227, Percent_Identity=27.3127753303965, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24758; Mature: 24627

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPDLVIFDCDGVLVDSEIVAARVEAEMLREAGYDITADEIAERYSGLTFKDIMIHIEK
CCCCCEEEEECCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHH
EAQMLLQASMIKQAEAKVDERLRAEVKAIPGVAEAAASLSVKKCVCSNSSEERIAIMLQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEH
TNLARFFEGVIFSSLATPTKRPKPAPDVFLYAAEQMGAEPAGTIVIEDSVHGIMGARTAG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEHHHHCCCCCCEEEECCCCCHHHHCCCCC
MRVIGFTGASHSHPRHASMLMEAGAETTISRMADLKSTIAALSEWSEEG
EEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKPDLVIFDCDGVLVDSEIVAARVEAEMLREAGYDITADEIAERYSGLTFKDIMIHIEK
CCCCEEEEECCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHH
EAQMLLQASMIKQAEAKVDERLRAEVKAIPGVAEAAASLSVKKCVCSNSSEERIAIMLQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEH
TNLARFFEGVIFSSLATPTKRPKPAPDVFLYAAEQMGAEPAGTIVIEDSVHGIMGARTAG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEHHHHCCCCCCEEEECCCCCHHHHCCCCC
MRVIGFTGASHSHPRHASMLMEAGAETTISRMADLKSTIAALSEWSEEG
EEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]