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The map label for this gene is cutS [H]

Identifier: 110632420

GI number: 110632420

Start: 80163

End: 80648

Strand: Direct

Name: cutS [H]

Synonym: Meso_0058

Alternate gene names: 110632420

Gene position: 80163-80648 (Clockwise)

Preceding gene: 110632419

Following gene: 110632421

Centisome position: 1.82

GC content: 61.93

Gene sequence:

>486_bases
ATGGCTGATATATCGATGGTGATCAATGGCCGCGAGGTGCGGGGCAGTGTGGAGGACAGGATGCTGCTCGTCCATTTCCT
GCGGGAGAGCCAAGGCCTTACAGGCACTCATGTCGGCTGCGACACGTCGCAGTGCGGCGCCTGCGTCGTGCATGTGGATG
GCAAGGCGGTAAAATCCTGCACCATGCTGGCCGCCCAGGCTTCCGGCTGCGAGGTTGTCACCATCGAGGGCCTTGCGAAA
GACGGGCAGTTGCACCCGGTGCAGGCCGCTTTCAAGGAGCATCACGGGCTGCAGTGCGGCTTCTGCACGCCAGGCATGGT
CATGAGCGCGGTCGATATGATTCGCCGTCATCCCGCAGGGCTCGATGAGAAGACCGTGCGGGCGGAACTGGAGGGCAATA
TCTGCCGCTGCACCGGCTATCACAACATTGTAAAGGCGATCATGGCCGCATCCGAAGAGATGAGCGGCAAGGCGCAAGCG
GCGTAG

Upstream 100 bases:

>100_bases
GCTCTCTCCGACTTAGAGGTTATGGACTCCTGCAACTTGTGAGGTAAGCTCGGCGCTATTACGCGCCTTTGAGTGCCGGT
CGCGAATTAGGAGGGAAGCC

Downstream 100 bases:

>100_bases
GAAAGCGAGTAGCTAGGAGGGGATTTAGAATAGGGACTGCAAATGTGCTGAGGATGCAACTCTCCTGAGTGCCGGCGCAG
GCGTGGCGATGCCATTCTTA

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MADISMVINGREVRGSVEDRMLLVHFLRESQGLTGTHVGCDTSQCGACVVHVDGKAVKSCTMLAAQASGCEVVTIEGLAK
DGQLHPVQAAFKEHHGLQCGFCTPGMVMSAVDMIRRHPAGLDEKTVRAELEGNICRCTGYHNIVKAIMAASEEMSGKAQA
A

Sequences:

>Translated_161_residues
MADISMVINGREVRGSVEDRMLLVHFLRESQGLTGTHVGCDTSQCGACVVHVDGKAVKSCTMLAAQASGCEVVTIEGLAK
DGQLHPVQAAFKEHHGLQCGFCTPGMVMSAVDMIRRHPAGLDEKTVRAELEGNICRCTGYHNIVKAIMAASEEMSGKAQA
A
>Mature_160_residues
ADISMVINGREVRGSVEDRMLLVHFLRESQGLTGTHVGCDTSQCGACVVHVDGKAVKSCTMLAAQASGCEVVTIEGLAKD
GQLHPVQAAFKEHHGLQCGFCTPGMVMSAVDMIRRHPAGLDEKTVRAELEGNICRCTGYHNIVKAIMAASEEMSGKAQAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=158, Percent_Identity=35.4430379746835, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI91823271, Length=151, Percent_Identity=36.4238410596026, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=40, Blast_Score=122, Evalue=8e-30,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=43.9189189189189, Blast_Score=115, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=165, Percent_Identity=36.3636363636364, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=33.9869281045752, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=160, Percent_Identity=33.75, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737937, Length=166, Percent_Identity=36.7469879518072, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24647201, Length=151, Percent_Identity=37.0860927152318, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24647199, Length=127, Percent_Identity=39.3700787401575, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647193, Length=133, Percent_Identity=37.593984962406, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647197, Length=133, Percent_Identity=34.5864661654135, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647195, Length=133, Percent_Identity=34.5864661654135, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17084; Mature: 16953

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
11.2 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
10.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADISMVINGREVRGSVEDRMLLVHFLRESQGLTGTHVGCDTSQCGACVVHVDGKAVKSC
CCCEEEEEECHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHH
TMLAAQASGCEVVTIEGLAKDGQLHPVQAAFKEHHGLQCGFCTPGMVMSAVDMIRRHPAG
HHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCC
LDEKTVRAELEGNICRCTGYHNIVKAIMAASEEMSGKAQAA
CCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ADISMVINGREVRGSVEDRMLLVHFLRESQGLTGTHVGCDTSQCGACVVHVDGKAVKSC
CCEEEEEECHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHH
TMLAAQASGCEVVTIEGLAKDGQLHPVQAAFKEHHGLQCGFCTPGMVMSAVDMIRRHPAG
HHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCC
LDEKTVRAELEGNICRCTGYHNIVKAIMAASEEMSGKAQAA
CCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]