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The map label for this gene is cutL [H]

Identifier: 110632421

GI number: 110632421

Start: 80786

End: 83131

Strand: Direct

Name: cutL [H]

Synonym: Meso_0059

Alternate gene names: 110632421

Gene position: 80786-83131 (Clockwise)

Preceding gene: 110632420

Following gene: 110632422

Centisome position: 1.83

GC content: 63.34

Gene sequence:

>2346_bases
ATGGGCATCGAAGGCATCGGCGCGCGGGTCACGCGCAAGGAGGACCAGCGGTTCGTCACCGGTCTCGGCCGTTACGTGGA
CGACATGGTCGTCCCCGGCATGAAATATGCGGTTTTTGTGCGCAGCCCGCACGCACACGCGACGATAAAGGCAATCGATA
CGGCCTCGGCAAAAGCTATGCCCGGCGTGATTGGCGTGCTCACCGGGCCGGAGCTCAAGAGCGACGGGATCGGCAATATC
ATTTGCGGCTGGATGATCCACTCCAAGGATGGCAGTCCCATGAAGATGGGAGCCTGGTCGCCGCTCGCCACCGATAAAGT
GCGCTATGTGGGCGATGCTGTCGCGATCGTCGTGGCCGAAACGCGAGGACAGGCCCGCGACGCGGCGGAGGCGGTAGCGG
TCGATTATGACGAGCTTCCCGCCGTCACCGATGCGCAAAAGGCGCTGGAAGCAGGCGCGCCGCAAATCCATCCGGAAGCC
CCGAACAATCTCATCTTCGATTGGGAGCTCGGCGATTCCGCGGATGCTGAGCGGGCGCTTGCGGGCGCGGCCCACGTCAC
CCGCATGCGGATCGTCAACAACCGCCTCATTCCTAACGCAATCGAGCCTCGCGCGGCTCTCGGGCATTATGACAAGGCGG
AGGACCATTTCACGCTCTGGACAACGAGTCAGAACCCGCATTTGGCCCGCCTCGTCATGAGCGCCTTCTACAATGTCGCG
CCGGAAAACAAGCTGCGCGTCATCGCGCCGGATGTGGGCGGCGGTTTCGGCTCCAAGATCTACATCTATCCGGAGGAGAT
CGTCTGCCTCTGGGCTTCGAAACGCACCGGCGTACCGGTGAAATGGGTGGCGGACCGCACGGAGAGCTTCCTCTGTGATG
CCCATGGACGCGATCATGTTACGGAAGTCTCGATGGGCTTCGACGCGGACAACCGAATCGTGGGCCTGAAGGTCGACACC
ATTGCCAATCTCGGCGCCTATATGTCGCTCTTCTCCTCCTGCGTGCCTACCTATCTCTACGCCACCTTGCTTTCCGGCCA
GTACGAAATCCCGCATATTCACTGCAACGTGCGCACCGTCTACACCAACACCGCACCTGTTGACGCCTATCGCGGCGCGG
GACGGCCGGAGGCAACTTACCTTTTGGAGCGGGTGATGGAGACCGCCGCGCGCGAGCTTGGCGTCTCGCCGGCGGAATTG
CGCCGCAAGAATTTCATCCGCGAATTCCCGCATCAAACGCCGGTGATCATGAATTATGACGCCGGGGATTATGAGGCGTC
GCTCGAAGCTGCCATGCGAGCTGCCGATTATGCAGGCTTCCCCGCCCGCCGCGAGGAGGCGAAGCGGCGCGGCAAGCTGC
GCGGCATCGGCATGAGCTGCTACATCGAGGCCTGCGGTCTTGCGCCCTCGCAGGCGGTGGGCAGCCTTGGCGCTGGCATC
GGGCTTTGGGAATCGGCTGAGGTGCGCGTGAACGCCGCCGGCACGATCGAGGTGCTCACTGGCTCGCACAGCCACGGCCA
GGGCCACGAGACCACCTTTGCCCAGGTGGTGGCGGACAGGCTGGGCGTGCCGCTTGATTCGGTGTCCGTCGTCCATGGCG
ATACCGACAAGGTGCAGATGGGCATGGGCACCTATGGCTCGCGCTCCGGGGCTGTTGGCATATCGGCCATCGTGAAGGCT
CTGGACAAGGTGGAGGCAAAGGCGAAGAAGATCGCCGCCCACCTGCTCGAGGCGGACGAGGGCGACATCGTCATCGAGAA
CGGCGAGGTGAAGGTGGCCGGCACGGACCGCAGCCTGCCCTGGTTACAGGTGGCGCTCGCCGCCTATACGGCGCACAACC
TGCCGGCTGGCATGGAGCCGGGCCTGAAGGAGACCTCCTTCTATGATCCGACCAATTTCACCTTCCCCGCGGGCTGCTAT
ATCTGCGAGGTGGAGGTCGATCCCGAGACGGGCGTGACGGAGATCGTGCAGTTCGTTGCGGCGGACGATTTCGGCACCAT
CATCAATCCCCTTATCGTTGAGGGGCAGGTCCATGGCGGCATCACGCAGGGCGTGGGACAGGCACTGCTCGAAGGCTGCG
TTTACGAACCGTCTTCCGGCCAGCTCGTCACGGCGTCCTATATGGACTACACCATGCCGCGTGCGAGTGACGTGCCCTCC
TTCCTCGTTTCGACAACCGTCACGCCAAGCCCGAGCAATCCACTGGGCATCAAGGGCTGTGGAGAGGCGGGCGCTATCGG
CTCCCCGCCTGCCGTGATCAATGCGATAACGGATGCCATCGGCAACAACGACCTGACCATGCCGGCCACGCCGCAAAGGG
TGTGGACGGCGCTCCGGAAGCACTGA

Upstream 100 bases:

>100_bases
TGCAAATGTGCTGAGGATGCAACTCTCCTGAGTGCCGGCGCAGGCGTGGCGATGCCATTCTTACGCGTTCCCTATTCGCT
CATTTCGACGGAGGAGCAAC

Downstream 100 bases:

>100_bases
CCGGCGCAAAGAGGAGAAGCCAATGTACCAAACCACTTACCATCGCCCCTCCTCGGTCACCGAGGCCGTAAAGATGCTGG
GCGAGGCCGAGGACGGAAAG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MGIEGIGARVTRKEDQRFVTGLGRYVDDMVVPGMKYAVFVRSPHAHATIKAIDTASAKAMPGVIGVLTGPELKSDGIGNI
ICGWMIHSKDGSPMKMGAWSPLATDKVRYVGDAVAIVVAETRGQARDAAEAVAVDYDELPAVTDAQKALEAGAPQIHPEA
PNNLIFDWELGDSADAERALAGAAHVTRMRIVNNRLIPNAIEPRAALGHYDKAEDHFTLWTTSQNPHLARLVMSAFYNVA
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKRTGVPVKWVADRTESFLCDAHGRDHVTEVSMGFDADNRIVGLKVDT
IANLGAYMSLFSSCVPTYLYATLLSGQYEIPHIHCNVRTVYTNTAPVDAYRGAGRPEATYLLERVMETAARELGVSPAEL
RRKNFIREFPHQTPVIMNYDAGDYEASLEAAMRAADYAGFPARREEAKRRGKLRGIGMSCYIEACGLAPSQAVGSLGAGI
GLWESAEVRVNAAGTIEVLTGSHSHGQGHETTFAQVVADRLGVPLDSVSVVHGDTDKVQMGMGTYGSRSGAVGISAIVKA
LDKVEAKAKKIAAHLLEADEGDIVIENGEVKVAGTDRSLPWLQVALAAYTAHNLPAGMEPGLKETSFYDPTNFTFPAGCY
ICEVEVDPETGVTEIVQFVAADDFGTIINPLIVEGQVHGGITQGVGQALLEGCVYEPSSGQLVTASYMDYTMPRASDVPS
FLVSTTVTPSPSNPLGIKGCGEAGAIGSPPAVINAITDAIGNNDLTMPATPQRVWTALRKH

Sequences:

>Translated_781_residues
MGIEGIGARVTRKEDQRFVTGLGRYVDDMVVPGMKYAVFVRSPHAHATIKAIDTASAKAMPGVIGVLTGPELKSDGIGNI
ICGWMIHSKDGSPMKMGAWSPLATDKVRYVGDAVAIVVAETRGQARDAAEAVAVDYDELPAVTDAQKALEAGAPQIHPEA
PNNLIFDWELGDSADAERALAGAAHVTRMRIVNNRLIPNAIEPRAALGHYDKAEDHFTLWTTSQNPHLARLVMSAFYNVA
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKRTGVPVKWVADRTESFLCDAHGRDHVTEVSMGFDADNRIVGLKVDT
IANLGAYMSLFSSCVPTYLYATLLSGQYEIPHIHCNVRTVYTNTAPVDAYRGAGRPEATYLLERVMETAARELGVSPAEL
RRKNFIREFPHQTPVIMNYDAGDYEASLEAAMRAADYAGFPARREEAKRRGKLRGIGMSCYIEACGLAPSQAVGSLGAGI
GLWESAEVRVNAAGTIEVLTGSHSHGQGHETTFAQVVADRLGVPLDSVSVVHGDTDKVQMGMGTYGSRSGAVGISAIVKA
LDKVEAKAKKIAAHLLEADEGDIVIENGEVKVAGTDRSLPWLQVALAAYTAHNLPAGMEPGLKETSFYDPTNFTFPAGCY
ICEVEVDPETGVTEIVQFVAADDFGTIINPLIVEGQVHGGITQGVGQALLEGCVYEPSSGQLVTASYMDYTMPRASDVPS
FLVSTTVTPSPSNPLGIKGCGEAGAIGSPPAVINAITDAIGNNDLTMPATPQRVWTALRKH
>Mature_780_residues
GIEGIGARVTRKEDQRFVTGLGRYVDDMVVPGMKYAVFVRSPHAHATIKAIDTASAKAMPGVIGVLTGPELKSDGIGNII
CGWMIHSKDGSPMKMGAWSPLATDKVRYVGDAVAIVVAETRGQARDAAEAVAVDYDELPAVTDAQKALEAGAPQIHPEAP
NNLIFDWELGDSADAERALAGAAHVTRMRIVNNRLIPNAIEPRAALGHYDKAEDHFTLWTTSQNPHLARLVMSAFYNVAP
ENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKRTGVPVKWVADRTESFLCDAHGRDHVTEVSMGFDADNRIVGLKVDTI
ANLGAYMSLFSSCVPTYLYATLLSGQYEIPHIHCNVRTVYTNTAPVDAYRGAGRPEATYLLERVMETAARELGVSPAELR
RKNFIREFPHQTPVIMNYDAGDYEASLEAAMRAADYAGFPARREEAKRRGKLRGIGMSCYIEACGLAPSQAVGSLGAGIG
LWESAEVRVNAAGTIEVLTGSHSHGQGHETTFAQVVADRLGVPLDSVSVVHGDTDKVQMGMGTYGSRSGAVGISAIVKAL
DKVEAKAKKIAAHLLEADEGDIVIENGEVKVAGTDRSLPWLQVALAAYTAHNLPAGMEPGLKETSFYDPTNFTFPAGCYI
CEVEVDPETGVTEIVQFVAADDFGTIINPLIVEGQVHGGITQGVGQALLEGCVYEPSSGQLVTASYMDYTMPRASDVPSF
LVSTTVTPSPSNPLGIKGCGEAGAIGSPPAVINAITDAIGNNDLTMPATPQRVWTALRKH

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=809, Percent_Identity=26.823238566131, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI91823271, Length=789, Percent_Identity=25.3485424588086, Blast_Score=157, Evalue=3e-38,
Organism=Escherichia coli, GI1789230, Length=769, Percent_Identity=29.9089726918075, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789246, Length=834, Percent_Identity=26.2589928057554, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1786478, Length=779, Percent_Identity=24.390243902439, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17539860, Length=798, Percent_Identity=24.6867167919799, Blast_Score=155, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17540638, Length=820, Percent_Identity=24.390243902439, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=563, Percent_Identity=24.5115452930728, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17737937, Length=791, Percent_Identity=25.2844500632111, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24647199, Length=760, Percent_Identity=21.8421052631579, Blast_Score=93, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24647195, Length=415, Percent_Identity=26.0240963855422, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647197, Length=415, Percent_Identity=26.0240963855422, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83417; Mature: 83286

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEGIGARVTRKEDQRFVTGLGRYVDDMVVPGMKYAVFVRSPHAHATIKAIDTASAKAM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCC
PGVIGVLTGPELKSDGIGNIICGWMIHSKDGSPMKMGAWSPLATDKVRYVGDAVAIVVAE
CCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCHHHHHCCEEEEEEEC
TRGQARDAAEAVAVDYDELPAVTDAQKALEAGAPQIHPEAPNNLIFDWELGDSADAERAL
CCCCCHHHHHHHEECHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHH
AGAAHVTRMRIVNNRLIPNAIEPRAALGHYDKAEDHFTLWTTSQNPHLARLVMSAFYNVA
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKRTGVPVKWVADRTESFLCDAHGRDHV
CCCCEEEEECCCCCCCCCEEEEECCEEEEEEECCCCCCCEEEECCCCHHEEECCCCCCCE
TEVSMGFDADNRIVGLKVDTIANLGAYMSLFSSCVPTYLYATLLSGQYEIPHIHCNVRTV
EEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
YTNTAPVDAYRGAGRPEATYLLERVMETAARELGVSPAELRRKNFIREFPHQTPVIMNYD
EECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECC
AGDYEASLEAAMRAADYAGFPARREEAKRRGKLRGIGMSCYIEACGLAPSQAVGSLGAGI
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHCCCC
GLWESAEVRVNAAGTIEVLTGSHSHGQGHETTFAQVVADRLGVPLDSVSVVHGDTDKVQM
CCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEE
GMGTYGSRSGAVGISAIVKALDKVEAKAKKIAAHLLEADEGDIVIENGEVKVAGTDRSLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCH
WLQVALAAYTAHNLPAGMEPGLKETSFYDPTNFTFPAGCYICEVEVDPETGVTEIVQFVA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHH
ADDFGTIINPLIVEGQVHGGITQGVGQALLEGCVYEPSSGQLVTASYMDYTMPRASDVPS
CCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCEEEEEHHHCCCCCCCCCCH
FLVSTTVTPSPSNPLGIKGCGEAGAIGSPPAVINAITDAIGNNDLTMPATPQRVWTALRK
HHHEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
H
C
>Mature Secondary Structure 
GIEGIGARVTRKEDQRFVTGLGRYVDDMVVPGMKYAVFVRSPHAHATIKAIDTASAKAM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCC
PGVIGVLTGPELKSDGIGNIICGWMIHSKDGSPMKMGAWSPLATDKVRYVGDAVAIVVAE
CCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCHHHHHCCEEEEEEEC
TRGQARDAAEAVAVDYDELPAVTDAQKALEAGAPQIHPEAPNNLIFDWELGDSADAERAL
CCCCCHHHHHHHEECHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHH
AGAAHVTRMRIVNNRLIPNAIEPRAALGHYDKAEDHFTLWTTSQNPHLARLVMSAFYNVA
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKRTGVPVKWVADRTESFLCDAHGRDHV
CCCCEEEEECCCCCCCCCEEEEECCEEEEEEECCCCCCCEEEECCCCHHEEECCCCCCCE
TEVSMGFDADNRIVGLKVDTIANLGAYMSLFSSCVPTYLYATLLSGQYEIPHIHCNVRTV
EEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
YTNTAPVDAYRGAGRPEATYLLERVMETAARELGVSPAELRRKNFIREFPHQTPVIMNYD
EECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECC
AGDYEASLEAAMRAADYAGFPARREEAKRRGKLRGIGMSCYIEACGLAPSQAVGSLGAGI
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHCCCC
GLWESAEVRVNAAGTIEVLTGSHSHGQGHETTFAQVVADRLGVPLDSVSVVHGDTDKVQM
CCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEE
GMGTYGSRSGAVGISAIVKALDKVEAKAKKIAAHLLEADEGDIVIENGEVKVAGTDRSLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCH
WLQVALAAYTAHNLPAGMEPGLKETSFYDPTNFTFPAGCYICEVEVDPETGVTEIVQFVA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHH
ADDFGTIINPLIVEGQVHGGITQGVGQALLEGCVYEPSSGQLVTASYMDYTMPRASDVPS
CCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCEEEEEHHHCCCCCCCCCCH
FLVSTTVTPSPSNPLGIKGCGEAGAIGSPPAVINAITDAIGNNDLTMPATPQRVWTALRK
HHHEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]