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The map label for this gene is pspA [C]

Identifier: 109948135

GI number: 109948135

Start: 1445558

End: 1446436

Strand: Reverse

Name: pspA [C]

Synonym: Hac_1658

Alternate gene names: 109948135

Gene position: 1446436-1445558 (Counterclockwise)

Preceding gene: 109948138

Following gene: 109948134

Centisome position: 93.08

GC content: 39.25

Gene sequence:

>879_bases
ATGTGGAGTTTCATTCAAAAAATCTTTAAGGCTTTAGTGATCATGCCTTTAGATTTTATTACGAAATATTTCAAGTCGTT
TGTGTTATTGTTGATTGTGTTAGTCTTTTTTAGTGCTAAAGAAAGTGCCCCAAGCACTCCGCCTAATCTCGCCAAACTCT
ATTTGAATGGGGCGATTTTTAGCACGGAATATTTTAACAAAGAAGTGGATAAGATTTTAAAAACCCCTAGCATTAAGGGC
GTTTTGCTTTTGATTGACTCCCCTGGTGGGGCTGTGTCAGCGAGCGTGGAATTGAGCGAAAAAATTGCTGATTTGAAGCA
AAAAATACCTGTTCTAGCGTATGCTAGGGGGGTTATGGCGAGCGGGAGTTATTATGCGGGCATGCAAGCGAGTGAAGTTT
ATGCCTCTAAAGCGAGCTTGATTGGCTCTATTGGGGTGATTTTTTCAGGTGCGAATGTGGAAAACTTGCTCAATAAAGTC
GGTGTAGCCACTCAAGGCGTGCATGCAGGCGAATATAAAGAAATAGGCACTTTCACTAGGGCGTGGAAACCTAACGAAAA
GGATTTTTTACAAAATTTAGTCAATGAGCAATACCAAATGTTTGTGAATGATGTCGCTAAAGCGAGAAACTTAAACCCCA
AGGATTATAAAAATTTTGCTGAAGGGAAAGTTTTTAGCGCTCAAAAGGCTTTAAGTTTAAAGCTTATTGATAAGATTAGC
ACGATCAAACAAGCCCAAAATCGTTTAATGGAATTGAGTAAGGTCAAAAAAGCTTATTGGCTAGAAAAAAGCCCTATGGA
GCGTTTTATTGAAAAAGCCACGCAATCAGCGACAAATATCATCACGCAAGCGCTTGGGTATCAATTATTGATGAGGTAA

Upstream 100 bases:

>100_bases
TTCTTATCTTAGGACAAAATTTACACGCCATGATTTAATCCTTAAAACATTTGAAGTATAATACACTCTTATAGTCAAAT
TTTAAGTTTAGGAAAATTGC

Downstream 100 bases:

>100_bases
GATGTTAGAATTCATTTTAAAATTCCAAGCCAAAGACGCTAAAGGCCTGGTGAGTGCGATTAGCACCACCATCGCTAACA
AGGGCTATAATATTGTCAAA

Product: protease IV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MWSFIQKIFKALVIMPLDFITKYFKSFVLLLIVLVFFSAKESAPSTPPNLAKLYLNGAIFSTEYFNKEVDKILKTPSIKG
VLLLIDSPGGAVSASVELSEKIADLKQKIPVLAYARGVMASGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKV
GVATQGVHAGEYKEIGTFTRAWKPNEKDFLQNLVNEQYQMFVNDVAKARNLNPKDYKNFAEGKVFSAQKALSLKLIDKIS
TIKQAQNRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQALGYQLLMR

Sequences:

>Translated_292_residues
MWSFIQKIFKALVIMPLDFITKYFKSFVLLLIVLVFFSAKESAPSTPPNLAKLYLNGAIFSTEYFNKEVDKILKTPSIKG
VLLLIDSPGGAVSASVELSEKIADLKQKIPVLAYARGVMASGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKV
GVATQGVHAGEYKEIGTFTRAWKPNEKDFLQNLVNEQYQMFVNDVAKARNLNPKDYKNFAEGKVFSAQKALSLKLIDKIS
TIKQAQNRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQALGYQLLMR
>Mature_292_residues
MWSFIQKIFKALVIMPLDFITKYFKSFVLLLIVLVFFSAKESAPSTPPNLAKLYLNGAIFSTEYFNKEVDKILKTPSIKG
VLLLIDSPGGAVSASVELSEKIADLKQKIPVLAYARGVMASGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKV
GVATQGVHAGEYKEIGTFTRAWKPNEKDFLQNLVNEQYQMFVNDVAKARNLNPKDYKNFAEGKVFSAQKALSLKLIDKIS
TIKQAQNRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQALGYQLLMR

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=247, Percent_Identity=29.5546558704453, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787527, Length=248, Percent_Identity=25.4032258064516, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 32464; Mature: 32464

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSFIQKIFKALVIMPLDFITKYFKSFVLLLIVLVFFSAKESAPSTPPNLAKLYLNGAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHH
STEYFNKEVDKILKTPSIKGVLLLIDSPGGAVSASVELSEKIADLKQKIPVLAYARGVMA
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHC
SGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKVGVATQGVHAGEYKEIGTFTR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHH
AWKPNEKDFLQNLVNEQYQMFVNDVAKARNLNPKDYKNFAEGKVFSAQKALSLKLIDKIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TIKQAQNRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQALGYQLLMR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWSFIQKIFKALVIMPLDFITKYFKSFVLLLIVLVFFSAKESAPSTPPNLAKLYLNGAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHH
STEYFNKEVDKILKTPSIKGVLLLIDSPGGAVSASVELSEKIADLKQKIPVLAYARGVMA
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHC
SGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKVGVATQGVHAGEYKEIGTFTR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHH
AWKPNEKDFLQNLVNEQYQMFVNDVAKARNLNPKDYKNFAEGKVFSAQKALSLKLIDKIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TIKQAQNRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQALGYQLLMR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]