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The map label for this gene is htpG

Identifier: 109948000

GI number: 109948000

Start: 1311605

End: 1313470

Strand: Reverse

Name: htpG

Synonym: Hac_1509

Alternate gene names: 109948000

Gene position: 1313470-1311605 (Counterclockwise)

Preceding gene: 109948003

Following gene: 109947997

Centisome position: 84.53

GC content: 35.64

Gene sequence:

>1866_bases
ATGTCTAATCAAGAATACACCTTTCAAACTGAAATCAACCAACTTTTGGATTTGATGATCCACTCTATGTATTCTAATAA
AGAGATTTTTTTAAGGGAGTTGATTTCTAATGCGAGCGACGCTTTGGATAAGCTCAATTATTTAATGCTAACCGATGAAA
AATTAAAAGGGCTAAAGATCACGCCTAGCATTCATTTGAGTTTTGATAGCCAGAAAAAAACCTTAACCATTAAAGATAAT
GGTATAGGCATGGATAAAAACGATTTGATCGAGCATTTAGGCACGATCGCTAAATCAGGCACTAAAAGTTTTTTAAGCGC
TTTGAGTGGGGATAAGAAAAAAGATAGCGCTTTAATTGGTCAATTTGGCGTGGGCTTTTATTCAGCGTTTATGGTAGCGG
GTAAAATTGTCGTTCAAACCAAAAAAGTAACTAGCGAGCAAGCTTATGCATGGGTGAGCGATGGTAAGGGTAAGTTTGAA
ATCAATGAATGTATCAAAGATGAGCAAGGCACAGAAATCACCCTCTTTTTAAAAGATGAAGACGCTAATTTTGCGAGCCG
TTGGGAGATTGATAGCATTGTTAAAAAGTATTCTGAGCATATCCCTTTCCCTATTTTTTTAACTTACACCGATACGAAAA
TGGAAGGCGAAGGGGATCACAAAAAAGAAGTTAAAGAAGAAAAATGCGAGCAAATCAATCAAGCGAGCGCTTTATGGAAA
ATGAATAAAAGCGAATTGAAAGACAAAGATTACAAAGAGTTTTATAAATCATTTGCACATGATAACAGTGAGCCTTTGAG
CTATATCCACAATAAAGTGGAAGGCTCTTTAGAATACACAACGCTTTTTTACATCCCTAGCGTTGCACCCTTTGACATGT
TTAGGGTGGATTATAAAAGTGGGGTCAAACTCTATGTTAAAAGGGTGTTTATCACTGATGATGACAAAGAATTACTGCCG
TCTTATTTGAGGTTTATTAAAGGCGTGATTGATAGCGAAGATCTACCCTTGAATGTGAGCCGCGAAATCTTACAGCAAAA
CAAGATTTTAGCCAATATCCGTTCTGCTTCAGTGAAAAAGATTTTAGGCGAGATTGAAAAATTAAGCAAGGATAATGAAA
ATTACCATAAATTCTATGAGCCTTTTGGGAAAGTGTTAAAAGAAGGCTTGTATGGGGATTTTGAAAACAAAGAAAAACTA
TTAGAATTATTAAGATTCTATTCTAAAGACAAAGAAAAATTGATTTCTTTAAAAGAATACAAAGAGAATCTAAAAGAAAA
TCAAAAAAGCATTTACTACCTTTTAGGCGAAAACCTGGATTTACTAAAGGCGTCCCCAATTTTAGAAAAATACGCTCAAA
AAGGCTATGATGTCTTGTTATTGAGCGATGAAATTGATGCGTTTGTGATGCCAAGCGTGAATGAATACGACAAAATGCCT
TTTAGAGACGCTAGCCATAGCGAGAGCTTGAAAGAGCTTGGTTTAGAAGAAATTAATGATGAGGTGAAAAACCAGTTTAA
AGATTTAATAAAGGCGTTTGAAGAAAATCTTAAAGATGAGATTAAGGGCGTGGAGCTTTCTAGCCATCTCACTTCAGCGG
TGGCTTTAATAGGTGATGAACAAAATGCGATGATGGCTAATTTGATGCGTCAAATGGGTCAAAATATGCCTGAAAGCAAA
AAAACTTTGGAATTAAACCCTAACCATGCGATTTTACAAAAACTCTTAAAATGCGAAGATAAAGAGCAGATGAGCGCTTT
TATTTGGTTGCTTTATGATGGGGCAAAGCTTTTAGAAAAAGGGGCTTTAAAAGATGCCAAAAGCTTTAATGAGCGTTTAA
ACAGCGTGCTATTGAAAGCGTTGTAG

Upstream 100 bases:

>100_bases
TTATCCGGCTTTTGCAAAAGATAGATCCACAGAATGCAAGCAGCTATTTAAACGCGCTTTTTATTGTATAATCTTAAAAA
TTTTATTTAAGGAAAAGTCA

Downstream 100 bases:

>100_bases
AGGTAAAAACTCTTTTTTAGGGGTTTAAACAGAACTGCTTTAAACCCTTTAAACACAAGCCTTTAGCGTTTGAAATGAAT
GAGTGCGATAAAAGCCTTAA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MSNQEYTFQTEINQLLDLMIHSMYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLKITPSIHLSFDSQKKTLTIKDN
GIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVAGKIVVQTKKVTSEQAYAWVSDGKGKFE
INECIKDEQGTEITLFLKDEDANFASRWEIDSIVKKYSEHIPFPIFLTYTDTKMEGEGDHKKEVKEEKCEQINQASALWK
MNKSELKDKDYKEFYKSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSVAPFDMFRVDYKSGVKLYVKRVFITDDDKELLP
SYLRFIKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILGEIEKLSKDNENYHKFYEPFGKVLKEGLYGDFENKEKL
LELLRFYSKDKEKLISLKEYKENLKENQKSIYYLLGENLDLLKASPILEKYAQKGYDVLLLSDEIDAFVMPSVNEYDKMP
FRDASHSESLKELGLEEINDEVKNQFKDLIKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANLMRQMGQNMPESK
KTLELNPNHAILQKLLKCEDKEQMSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL

Sequences:

>Translated_621_residues
MSNQEYTFQTEINQLLDLMIHSMYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLKITPSIHLSFDSQKKTLTIKDN
GIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVAGKIVVQTKKVTSEQAYAWVSDGKGKFE
INECIKDEQGTEITLFLKDEDANFASRWEIDSIVKKYSEHIPFPIFLTYTDTKMEGEGDHKKEVKEEKCEQINQASALWK
MNKSELKDKDYKEFYKSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSVAPFDMFRVDYKSGVKLYVKRVFITDDDKELLP
SYLRFIKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILGEIEKLSKDNENYHKFYEPFGKVLKEGLYGDFENKEKL
LELLRFYSKDKEKLISLKEYKENLKENQKSIYYLLGENLDLLKASPILEKYAQKGYDVLLLSDEIDAFVMPSVNEYDKMP
FRDASHSESLKELGLEEINDEVKNQFKDLIKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANLMRQMGQNMPESK
KTLELNPNHAILQKLLKCEDKEQMSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL
>Mature_620_residues
SNQEYTFQTEINQLLDLMIHSMYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLKITPSIHLSFDSQKKTLTIKDNG
IGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVAGKIVVQTKKVTSEQAYAWVSDGKGKFEI
NECIKDEQGTEITLFLKDEDANFASRWEIDSIVKKYSEHIPFPIFLTYTDTKMEGEGDHKKEVKEEKCEQINQASALWKM
NKSELKDKDYKEFYKSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSVAPFDMFRVDYKSGVKLYVKRVFITDDDKELLPS
YLRFIKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILGEIEKLSKDNENYHKFYEPFGKVLKEGLYGDFENKEKLL
ELLRFYSKDKEKLISLKEYKENLKENQKSIYYLLGENLDLLKASPILEKYAQKGYDVLLLSDEIDAFVMPSVNEYDKMPF
RDASHSESLKELGLEEINDEVKNQFKDLIKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANLMRQMGQNMPESKK
TLELNPNHAILQKLLKCEDKEQMSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=689, Percent_Identity=34.5428156748911, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI155722983, Length=654, Percent_Identity=33.9449541284404, Blast_Score=348, Evalue=6e-96,
Organism=Homo sapiens, GI154146191, Length=401, Percent_Identity=37.4064837905237, Blast_Score=239, Evalue=6e-63,
Organism=Homo sapiens, GI20149594, Length=403, Percent_Identity=36.2282878411911, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI153792590, Length=401, Percent_Identity=37.4064837905237, Blast_Score=237, Evalue=2e-62,
Organism=Escherichia coli, GI1786679, Length=639, Percent_Identity=46.1658841940532, Blast_Score=548, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17559162, Length=662, Percent_Identity=38.9728096676737, Blast_Score=405, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17542208, Length=677, Percent_Identity=37.0753323485968, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=32.7131782945736, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=36.6132723112128, Blast_Score=259, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=687, Percent_Identity=37.7001455604076, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=37.9411764705882, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI17647529, Length=650, Percent_Identity=37.0769230769231, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI21357739, Length=632, Percent_Identity=37.8164556962025, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24586016, Length=645, Percent_Identity=32.8682170542636, Blast_Score=314, Evalue=1e-85,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_HELAH (Q17VU7)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_665228.1
- ProteinModelPortal:   Q17VU7
- STRING:   Q17VU7
- GeneID:   4177543
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1509
- NMPDR:   fig|382638.8.peg.1461
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   KYIANAY
- PhylomeDB:   Q17VU7
- ProtClustDB:   PRK05218
- BioCyc:   HACI382638:HAC_1509-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71286; Mature: 71155

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQEYTFQTEINQLLDLMIHSMYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLKI
CCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
TPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIG
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHH
QFGVGFYSAFMVAGKIVVQTKKVTSEQAYAWVSDGKGKFEINECIKDEQGTEITLFLKDE
HHHHHHHHHHHHHHHHHEEEHHHCCHHHEEEECCCCCCEEHHHHHCCCCCCEEEEEEECC
DANFASRWEIDSIVKKYSEHIPFPIFLTYTDTKMEGEGDHKKEVKEEKCEQINQASALWK
CCCCHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MNKSELKDKDYKEFYKSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSVAPFDMFRVDYKS
CCHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHC
GVKLYVKRVFITDDDKELLPSYLRFIKGVIDSEDLPLNVSREILQQNKILANIRSASVKK
CCEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ILGEIEKLSKDNENYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEY
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
KENLKENQKSIYYLLGENLDLLKASPILEKYAQKGYDVLLLSDEIDAFVMPSVNEYDKMP
HHHHHHCCCEEEEEECCCCCHHHCCHHHHHHHHCCCEEEEEECCCCEEECCCCCHHHCCC
FRDASHSESLKELGLEEINDEVKNQFKDLIKAFEENLKDEIKGVELSSHLTSAVALIGDE
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
QNAMMANLMRQMGQNMPESKKTLELNPNHAILQKLLKCEDKEQMSAFIWLLYDGAKLLEK
CHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHH
GALKDAKSFNERLNSVLLKAL
HCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNQEYTFQTEINQLLDLMIHSMYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLKI
CCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
TPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIG
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHH
QFGVGFYSAFMVAGKIVVQTKKVTSEQAYAWVSDGKGKFEINECIKDEQGTEITLFLKDE
HHHHHHHHHHHHHHHHHEEEHHHCCHHHEEEECCCCCCEEHHHHHCCCCCCEEEEEEECC
DANFASRWEIDSIVKKYSEHIPFPIFLTYTDTKMEGEGDHKKEVKEEKCEQINQASALWK
CCCCHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MNKSELKDKDYKEFYKSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSVAPFDMFRVDYKS
CCHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHC
GVKLYVKRVFITDDDKELLPSYLRFIKGVIDSEDLPLNVSREILQQNKILANIRSASVKK
CCEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ILGEIEKLSKDNENYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEY
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
KENLKENQKSIYYLLGENLDLLKASPILEKYAQKGYDVLLLSDEIDAFVMPSVNEYDKMP
HHHHHHCCCEEEEEECCCCCHHHCCHHHHHHHHCCCEEEEEECCCCEEECCCCCHHHCCC
FRDASHSESLKELGLEEINDEVKNQFKDLIKAFEENLKDEIKGVELSSHLTSAVALIGDE
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
QNAMMANLMRQMGQNMPESKKTLELNPNHAILQKLLKCEDKEQMSAFIWLLYDGAKLLEK
CHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHH
GALKDAKSFNERLNSVLLKAL
HCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA