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The map label for this gene is hypD [H]

Identifier: 109947801

GI number: 109947801

Start: 1102108

End: 1103220

Strand: Reverse

Name: hypD [H]

Synonym: Hac_1286

Alternate gene names: 109947801

Gene position: 1103220-1102108 (Counterclockwise)

Preceding gene: 109947802

Following gene: 109947799

Centisome position: 71.0

GC content: 42.23

Gene sequence:

>1113_bases
ATGAGCGTTAATCATCTCATTTCGCCTTTTAGAGACAAGCAAACCATTTTAGCGCTCTCTAATGAAATCAAAAAACTCGC
CTCCAAACTCACAGAAAAATTAGTCATCATGGAAGTGTGCGGAGGGCATACGCATTCTATAATGAAATACGGGCTTTTGG
ATCTAATGCCCAATCATTTAGAGTTTGTGCATGGACCGGGTTGCCCGGTATGCGTGATGCCAAGAGTACGCCTGGATGAA
GCTTATGAGCTCGCTAGCATGAAAGATAGCGTTATTTTAAGTTTAGGGGATATGATGAAAGTCCCTGGGAGCTATGGGAG
TTTGATAAAAGCGAGGGAAAAGGGGCTGGATGCACGCTTTTTGTATTCGCCCATGCAAGCTTTAGAAATCGCTAAAGAAA
ACCCGCATAAAAAAGTCATTTATTTTGCGATCGGTTTTGAAACCACCACACCCATGACGGCAAGCGTTTTACTCAACGCA
AAAAAAGAAAAGATCAAAAATCTTTTTTTCCACATTAACCACATTTTAGTGCCCCCAAGCGTGAGCGCGATTTTAGAAGA
TCCAACATGCCCAATCAACGCCCTTTTAGCCCCTAGCCATGTGAGCGTGATAAGCGGCGCTCAAATCTATACCCCTTTAG
TGGAGTGCTTTAATATCCCCATTATTGTGAGCGGTTTTGAGCCGGTGGATATATTAGAAAGCGTGTTAATGCTACTAAAA
CAAACCCTAAACAAAGAAGCCAAGCTAGAAATCCAGTATAAAAGAGTGGTTAGTTATGAGGGGAATGTAAAAGCGCAAGA
GTTAGTGCGTGAATGCATGGAAATAAGAGAAAATTTTGAATGGAGAGGCTTGGGGAATATCAAAAATTCCGCTCTAAAAC
TCAAAGAAACATTCGCCTCTTATGACGCTGAAAAAGCGTTTAAAGAATATTTAACCCACAAAACCATAAAAGAAAACAAA
GCATGCAAATGTGCAGAGATCTTAAAAGGCAACGCCAAGCCTTTAGATTGCCCACTATTTGCAAAAACTTGCACCCCACA
AGATCCGATCGGCAGTTGCATGGTCAGCTCTGAGGGGGCGTGTTCGGCGTATTATCGTTACAAGCGCGTTTGA

Upstream 100 bases:

>100_bases
GCTATGTGATGAGTAAGATTGATGAAAAAGAAGCCCTAGAATCCATTGAGCTCTATCAAGAAATGATCGCTAAAATGAAT
GAAGTGCATGAATAATCGCA

Downstream 100 bases:

>100_bases
GTTTTAAAAATTGCTCTTTGGTGAAAGCGCTCAAATTCTCGCAATTGACATTGACGCTAACCGGTTTTTTAGGGGTTTTT
AAAACCGGTTTTTGGTAAGG

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSVNHLISPFRDKQTILALSNEIKKLASKLTEKLVIMEVCGGHTHSIMKYGLLDLMPNHLEFVHGPGCPVCVMPRVRLDE
AYELASMKDSVILSLGDMMKVPGSYGSLIKAREKGLDARFLYSPMQALEIAKENPHKKVIYFAIGFETTTPMTASVLLNA
KKEKIKNLFFHINHILVPPSVSAILEDPTCPINALLAPSHVSVISGAQIYTPLVECFNIPIIVSGFEPVDILESVLMLLK
QTLNKEAKLEIQYKRVVSYEGNVKAQELVRECMEIRENFEWRGLGNIKNSALKLKETFASYDAEKAFKEYLTHKTIKENK
ACKCAEILKGNAKPLDCPLFAKTCTPQDPIGSCMVSSEGACSAYYRYKRV

Sequences:

>Translated_370_residues
MSVNHLISPFRDKQTILALSNEIKKLASKLTEKLVIMEVCGGHTHSIMKYGLLDLMPNHLEFVHGPGCPVCVMPRVRLDE
AYELASMKDSVILSLGDMMKVPGSYGSLIKAREKGLDARFLYSPMQALEIAKENPHKKVIYFAIGFETTTPMTASVLLNA
KKEKIKNLFFHINHILVPPSVSAILEDPTCPINALLAPSHVSVISGAQIYTPLVECFNIPIIVSGFEPVDILESVLMLLK
QTLNKEAKLEIQYKRVVSYEGNVKAQELVRECMEIRENFEWRGLGNIKNSALKLKETFASYDAEKAFKEYLTHKTIKENK
ACKCAEILKGNAKPLDCPLFAKTCTPQDPIGSCMVSSEGACSAYYRYKRV
>Mature_369_residues
SVNHLISPFRDKQTILALSNEIKKLASKLTEKLVIMEVCGGHTHSIMKYGLLDLMPNHLEFVHGPGCPVCVMPRVRLDEA
YELASMKDSVILSLGDMMKVPGSYGSLIKAREKGLDARFLYSPMQALEIAKENPHKKVIYFAIGFETTTPMTASVLLNAK
KEKIKNLFFHINHILVPPSVSAILEDPTCPINALLAPSHVSVISGAQIYTPLVECFNIPIIVSGFEPVDILESVLMLLKQ
TLNKEAKLEIQYKRVVSYEGNVKAQELVRECMEIRENFEWRGLGNIKNSALKLKETFASYDAEKAFKEYLTHKTIKENKA
CKCAEILKGNAKPLDCPLFAKTCTPQDPIGSCMVSSEGACSAYYRYKRV

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=368, Percent_Identity=42.6630434782609, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41317; Mature: 41186

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNHLISPFRDKQTILALSNEIKKLASKLTEKLVIMEVCGGHTHSIMKYGLLDLMPNHL
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
EFVHGPGCPVCVMPRVRLDEAYELASMKDSVILSLGDMMKVPGSYGSLIKAREKGLDARF
HEECCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHH
LYSPMQALEIAKENPHKKVIYFAIGFETTTPMTASVLLNAKKEKIKNLFFHINHILVPPS
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
VSAILEDPTCPINALLAPSHVSVISGAQIYTPLVECFNIPIIVSGFEPVDILESVLMLLK
HHHHHCCCCCCCHHEECCCHHHHHCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
QTLNKEAKLEIQYKRVVSYEGNVKAQELVRECMEIRENFEWRGLGNIKNSALKLKETFAS
HHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
YDAEKAFKEYLTHKTIKENKACKCAEILKGNAKPLDCPLFAKTCTPQDPIGSCMVSSEGA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEECCCCC
CSAYYRYKRV
HHHHHHHCCC
>Mature Secondary Structure 
SVNHLISPFRDKQTILALSNEIKKLASKLTEKLVIMEVCGGHTHSIMKYGLLDLMPNHL
CCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
EFVHGPGCPVCVMPRVRLDEAYELASMKDSVILSLGDMMKVPGSYGSLIKAREKGLDARF
HEECCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHH
LYSPMQALEIAKENPHKKVIYFAIGFETTTPMTASVLLNAKKEKIKNLFFHINHILVPPS
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
VSAILEDPTCPINALLAPSHVSVISGAQIYTPLVECFNIPIIVSGFEPVDILESVLMLLK
HHHHHCCCCCCCHHEECCCHHHHHCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
QTLNKEAKLEIQYKRVVSYEGNVKAQELVRECMEIRENFEWRGLGNIKNSALKLKETFAS
HHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
YDAEKAFKEYLTHKTIKENKACKCAEILKGNAKPLDCPLFAKTCTPQDPIGSCMVSSEGA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEECCCCC
CSAYYRYKRV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]