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The map label for this gene is mutS [H]

Identifier: 109947309

GI number: 109947309

Start: 648666

End: 650909

Strand: Direct

Name: mutS [H]

Synonym: Hac_0739

Alternate gene names: 109947309

Gene position: 648666-650909 (Clockwise)

Preceding gene: 109947308

Following gene: 109947312

Centisome position: 41.74

GC content: 36.05

Gene sequence:

>2244_bases
ATGATGAATCACACTATACCAAAACCCTTAGAAGAAAGCCTAGATTTAAAAGAGTTTATCGCTCTTTTTAAAACCTTTTT
TGCAAAAGAAGGGGGTATTATTGCTTTAGAAAACGATCTCAAACAGGCTTTCACTTATTTGAATGAAGTGGATGCGATCG
GTTTGCCCACCCCTAAAAGCGTGAAAGAGAGCGATCTTATTCTTATCAAACTCACCAAATTAGGAACACTCCATTTAGAT
GAAATTGACGAGATTGTCAAACGATTGCACTACATTGTCATTTTACAAAACACTTTTAAAAATTTTACGCATTTAAAATT
TTATGAACGCCTTAATGCTATTGTTTTGCCTTTATTTTTTAATGATTTAATCCATTTATTTGATGATGAAGGGAAAATCA
AACAAGGGGCTAACGCCACCCTAGACGCTTTAAATGAGAGTTTGAACCGCCTTAAAAAAGAGAGTGCTAAAATCATTCAC
AATTACGCGCATTCTAAAGAGCTTGCCCCTTATTTAGTGGATACCCAAAGCCATCTTAAGCATGGTTATGAATGCCTTTT
GTTAAAAAGCGGGTTTTCTAGAGCGATTAAGGGCGTTGTTCTAGAAAGGAGCGCTAATGGTTATTTTTATCTTTTGCCTG
AAAGCGCGCAAAAAATCGCGCAAAAAATCTCACAAATTGATAATGAAATAGATTGCTGTATTATTGAAATGTGTCAAACT
TTAAGTCATAGCTTGCAAAAACACCTTTTATTTTTAAGATTCCTTTTCAAAGAATTTGATTTTTTAGACAGCTTGCAAGC
CCGGCTCAATTTCGCTAAAGCCTACAATTTAGAATTTGTCATGCCAAGTTTTACGCAAAAGAAAATGGTTTTAGAAAACT
TTTCGCACCCCATTTTAAAAGATCCAAAGCCCTTAAATTTGAAGTTTGAAAAATCAATGCTCGCTGTTACTGGCGTGAAT
GCTGGCGGGAAAACCATGCTCTTAAAATCGCTTTTAAGTGCGGCTTTTTTAAGCAAATACCTCATTCCTATGAAAATCAA
TGCTCATCATTCGGTTATTCCTTATTTTAAAGAAATCCACGCTATTATCAACGACCCTCAAAATAGTGCAAACAATATCT
CTACTTTTGCAGGCAGAATGAAGCAATTCAGTGCTCTTTTATCCAAAGAAAACATGCTTTTAGGCGTTGATGAAATTGAG
TTAGGGACTGATGCTGATGAAGCGAGCAGTTTGTATAAAACTTTGTTGGAAAAATTGCTTGAACAAAACAATCAAATCAT
TATCACCACCCACCACAAACGCCTGAGCGTGTTAATGGCAGAAAATCAAGAAGTGGAATTACTAGCTGCTCTTTATGATG
AAGAAAAAGAACGGCCCACTTACACTTTTTTAAAAGGGGTTGTTGGCAAAAGTTATGCGTTTGAAACCGCTCTGCGTTAT
GGCGTGCCGCGTTTTTTGATTGAAAAAGCGAAGGCATTTTATGGCGAAGATAAGGAAAAATTGAATGTTTTGATTGAAAA
TTCAAGCACGCTAGAAAGGGAATTGAAACAAAAAAATGAACATTTAGAGAACGCTTTAAAAGAGCAAGAAGGTTTAAAAA
ACGCTTGGCTTTTAGAAATAGAAAAACAAAAAGAAATCTTTCACAATAAAAAATTGGAATTGGAAAAATCCTACCAACAA
GCCTTGAATGTGCTAAAAAGCGAAGTCGCTTCAAAAGATACAAGCTCTATGCATAAAGAAATTCATAAAGCGAGCGAGAT
TTTAAACAAACATAAAAGTAGTCATGAAACCCCACAAATCACAACAAGCTTTCAAGCTAACGAAAAAGCACGCTATAAAA
ATGAAAGCGTGCTGATCGCACAGATTTTAGATAAGGGCTATTATTTGATAGAAACCGAGTTTGGCATGCGCTTAAAAGTG
CATGGGAGTTTGTTGAAAAAAATCCAAAAACCCCCTAAAAACAAATTCAAACCCCCTAAAACAATCATTCCTAAACCTAA
AGAAGCGAGTTTGCACCTTGATTTAAGGGGACAACGCAGCGAAGAAGCTTTGGATTCACTGGACGCCTTTTTAAACAACG
CGCTTTTAGGAGGCTTTGAAGAAGTGCTTGTTTGTCATGGCAAAGGGAGCGGGATTTTAGAAAAGTTTGTGAAAGAATTT
TTAAAAAACCACCCTAAAGTGGTAAGCTTTAGCGACGCTCCTATCAATTTAGGCGGTAGTGGGGTTAAAATCGTTAAATT
GTAG

Upstream 100 bases:

>100_bases
CTTTGAGTTTTTTGGGTAAAAAACAAACCCCCATGAAAGATGTTCTTGTGGATTTAGATTCTTGTCAAACGCTTCAAAAA
GATCCCTTAATCCAACCCTA

Downstream 100 bases:

>100_bases
GTTTTGGTGTTTGTTTTCAAAAATCTTATCGGATTTGTTTGTCTCAAAGATTTATTTTAAAAATCATAAATAGTCAAACG
AGCTCACACAAACCGCCACC

Product: recombination and DNA strand exchange inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MMNHTIPKPLEESLDLKEFIALFKTFFAKEGGIIALENDLKQAFTYLNEVDAIGLPTPKSVKESDLILIKLTKLGTLHLD
EIDEIVKRLHYIVILQNTFKNFTHLKFYERLNAIVLPLFFNDLIHLFDDEGKIKQGANATLDALNESLNRLKKESAKIIH
NYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSRAIKGVVLERSANGYFYLLPESAQKIAQKISQIDNEIDCCIIEMCQT
LSHSLQKHLLFLRFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILKDPKPLNLKFEKSMLAVTGVN
AGGKTMLLKSLLSAAFLSKYLIPMKINAHHSVIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIE
LGTDADEASSLYKTLLEKLLEQNNQIIITTHHKRLSVLMAENQEVELLAALYDEEKERPTYTFLKGVVGKSYAFETALRY
GVPRFLIEKAKAFYGEDKEKLNVLIENSSTLERELKQKNEHLENALKEQEGLKNAWLLEIEKQKEIFHNKKLELEKSYQQ
ALNVLKSEVASKDTSSMHKEIHKASEILNKHKSSHETPQITTSFQANEKARYKNESVLIAQILDKGYYLIETEFGMRLKV
HGSLLKKIQKPPKNKFKPPKTIIPKPKEASLHLDLRGQRSEEALDSLDAFLNNALLGGFEEVLVCHGKGSGILEKFVKEF
LKNHPKVVSFSDAPINLGGSGVKIVKL

Sequences:

>Translated_747_residues
MMNHTIPKPLEESLDLKEFIALFKTFFAKEGGIIALENDLKQAFTYLNEVDAIGLPTPKSVKESDLILIKLTKLGTLHLD
EIDEIVKRLHYIVILQNTFKNFTHLKFYERLNAIVLPLFFNDLIHLFDDEGKIKQGANATLDALNESLNRLKKESAKIIH
NYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSRAIKGVVLERSANGYFYLLPESAQKIAQKISQIDNEIDCCIIEMCQT
LSHSLQKHLLFLRFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILKDPKPLNLKFEKSMLAVTGVN
AGGKTMLLKSLLSAAFLSKYLIPMKINAHHSVIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIE
LGTDADEASSLYKTLLEKLLEQNNQIIITTHHKRLSVLMAENQEVELLAALYDEEKERPTYTFLKGVVGKSYAFETALRY
GVPRFLIEKAKAFYGEDKEKLNVLIENSSTLERELKQKNEHLENALKEQEGLKNAWLLEIEKQKEIFHNKKLELEKSYQQ
ALNVLKSEVASKDTSSMHKEIHKASEILNKHKSSHETPQITTSFQANEKARYKNESVLIAQILDKGYYLIETEFGMRLKV
HGSLLKKIQKPPKNKFKPPKTIIPKPKEASLHLDLRGQRSEEALDSLDAFLNNALLGGFEEVLVCHGKGSGILEKFVKEF
LKNHPKVVSFSDAPINLGGSGVKIVKL
>Mature_747_residues
MMNHTIPKPLEESLDLKEFIALFKTFFAKEGGIIALENDLKQAFTYLNEVDAIGLPTPKSVKESDLILIKLTKLGTLHLD
EIDEIVKRLHYIVILQNTFKNFTHLKFYERLNAIVLPLFFNDLIHLFDDEGKIKQGANATLDALNESLNRLKKESAKIIH
NYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSRAIKGVVLERSANGYFYLLPESAQKIAQKISQIDNEIDCCIIEMCQT
LSHSLQKHLLFLRFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILKDPKPLNLKFEKSMLAVTGVN
AGGKTMLLKSLLSAAFLSKYLIPMKINAHHSVIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIE
LGTDADEASSLYKTLLEKLLEQNNQIIITTHHKRLSVLMAENQEVELLAALYDEEKERPTYTFLKGVVGKSYAFETALRY
GVPRFLIEKAKAFYGEDKEKLNVLIENSSTLERELKQKNEHLENALKEQEGLKNAWLLEIEKQKEIFHNKKLELEKSYQQ
ALNVLKSEVASKDTSSMHKEIHKASEILNKHKSSHETPQITTSFQANEKARYKNESVLIAQILDKGYYLIETEFGMRLKV
HGSLLKKIQKPPKNKFKPPKTIIPKPKEASLHLDLRGQRSEEALDSLDAFLNNALLGGFEEVLVCHGKGSGILEKFVKEF
LKNHPKVVSFSDAPINLGGSGVKIVKL

Specific function: This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Possible That It Carries Out The Mismatch Recognition Step. This Protein Has A Weak Atpase Activity. [C]

COG id: COG1193

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Smr domain [H]

Homologues:

Organism=Escherichia coli, GI1789089, Length=250, Percent_Identity=27.2, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005747
- InterPro:   IPR000432
- InterPro:   IPR007696
- InterPro:   IPR002625 [H]

Pfam domain/function: PF00488 MutS_V; PF01713 Smr [H]

EC number: NA

Molecular weight: Translated: 84965; Mature: 84965

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50828 SMR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNHTIPKPLEESLDLKEFIALFKTFFAKEGGIIALENDLKQAFTYLNEVDAIGLPTPKS
CCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCC
VKESDLILIKLTKLGTLHLDEIDEIVKRLHYIVILQNTFKNFTHLKFYERLNAIVLPLFF
CCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHEEHHHHH
NDLIHLFDDEGKIKQGANATLDALNESLNRLKKESAKIIHNYAHSKELAPYLVDTQSHLK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHC
HGYECLLLKSGFSRAIKGVVLERSANGYFYLLPESAQKIAQKISQIDNEIDCCIIEMCQT
CCCEEEEECCCHHHHHHHHHEEECCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSHSLQKHLLFLRFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCCCC
DPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKYLIPMKINAHHSVIPYFKEIH
CCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
AIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLL
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCHHHHHHHHHHHHHHHH
EQNNQIIITTHHKRLSVLMAENQEVELLAALYDEEKERPTYTFLKGVVGKSYAFETALRY
HCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
GVPRFLIEKAKAFYGEDKEKLNVLIENSSTLERELKQKNEHLENALKEQEGLKNAWLLEI
CCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
EKQKEIFHNKKLELEKSYQQALNVLKSEVASKDTSSMHKEIHKASEILNKHKSSHETPQI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
TTSFQANEKARYKNESVLIAQILDKGYYLIETEFGMRLKVHGSLLKKIQKPPKNKFKPPK
EECCCCCCHHHHCCCCCHHHHHHHCCEEEEEECCCCEEEECHHHHHHHCCCCCCCCCCCC
TIIPKPKEASLHLDLRGQRSEEALDSLDAFLNNALLGGFEEVLVCHGKGSGILEKFVKEF
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHH
LKNHPKVVSFSDAPINLGGSGVKIVKL
HHCCCCEEEECCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MMNHTIPKPLEESLDLKEFIALFKTFFAKEGGIIALENDLKQAFTYLNEVDAIGLPTPKS
CCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCC
VKESDLILIKLTKLGTLHLDEIDEIVKRLHYIVILQNTFKNFTHLKFYERLNAIVLPLFF
CCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHEEHHHHH
NDLIHLFDDEGKIKQGANATLDALNESLNRLKKESAKIIHNYAHSKELAPYLVDTQSHLK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHC
HGYECLLLKSGFSRAIKGVVLERSANGYFYLLPESAQKIAQKISQIDNEIDCCIIEMCQT
CCCEEEEECCCHHHHHHHHHEEECCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSHSLQKHLLFLRFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCCCC
DPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKYLIPMKINAHHSVIPYFKEIH
CCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
AIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLL
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCHHHHHHHHHHHHHHHH
EQNNQIIITTHHKRLSVLMAENQEVELLAALYDEEKERPTYTFLKGVVGKSYAFETALRY
HCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
GVPRFLIEKAKAFYGEDKEKLNVLIENSSTLERELKQKNEHLENALKEQEGLKNAWLLEI
CCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
EKQKEIFHNKKLELEKSYQQALNVLKSEVASKDTSSMHKEIHKASEILNKHKSSHETPQI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
TTSFQANEKARYKNESVLIAQILDKGYYLIETEFGMRLKVHGSLLKKIQKPPKNKFKPPK
EECCCCCCHHHHCCCCCHHHHHHHCCEEEEEECCCCEEEECHHHHHHHCCCCCCCCCCCC
TIIPKPKEASLHLDLRGQRSEEALDSLDAFLNNALLGGFEEVLVCHGKGSGILEKFVKEF
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHH
LKNHPKVVSFSDAPINLGGSGVKIVKL
HHCCCCEEEECCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]