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The map label for this gene is aroA

Identifier: 109947061

GI number: 109947061

Start: 406819

End: 408108

Strand: Reverse

Name: aroA

Synonym: Hac_0459

Alternate gene names: 109947061

Gene position: 408108-406819 (Counterclockwise)

Preceding gene: 109947062

Following gene: 109947060

Centisome position: 26.26

GC content: 37.75

Gene sequence:

>1290_bases
TTGATAGAGCTTGATATTAACGCTAGCGACAAATCGCTCTCACACAGAGCCGTCATTTTTAGTCTGCTTGCCAAAAAGCC
TTGTTTTGTGCGGAATTTTTTAATGGGAGGAGATTGTTTAAGTTCTTTAGAAATCGCTCAAAATTTAGGGGCTAGAGTAG
AGAATATCGCCAAAAATTCTTTTAAGATCACGCCCCCATGGGCCTTAAAAGAGCCTAGAAAGATTTTAAATTGTAACAAT
TCTGGCACTAGCATGCGTTTATACAGTGGGCTTTTAAGCGCTCAAAAAGGGCTTTTTGTTTTAAGTGGGGACAATTCCCT
AAATTCACGCCCCATGAAAAGAATCATTGAGCCTTTAAAGGCTTTTGGGACAAAAATTTTGGGGAGAGAGGATAACCATT
TCGCCCCTTTAGTGATCTTAGGGAGTCCTTTAAAAGCTTGCGATTATGAAAGCCCTATCGCTTCAGCCCAAGTCAAAAGC
GCTTTTATTTTAAGTGCCTTGCAAGCTCAAGGCACAAGCACCTATAGAGAAAGCGAGCTTAGCCGTAACCACACAGAAAT
CATGCTTAAAAGTTTAGGAGCTAATATTAAAGATCAGGACGGCGTTTTAAAAATTTCGCCCCTAGAAAAACCCCTAGAAG
CTTTTGATTTTAAGATAGCCAATGATCCGTCTAGTGCATTTTTTTTCGCTCTCGCTTGCGCTATTCTGCCAAAAAGCCGC
CTTCTTTTAAAAAATGTCCTACTCAATCCCACTCGCATAGAAGCTTTTGAAGTTTTGAAAAAAATGGGCACTCATATAGA
GTGTGTTATCAAGTCCAAAGATTTAGAAATTATAGGCGATATTTATATAGAACATGCCCTTTTAAAAGCGATCACTATTG
ATCAAAATATCGCTAGTCTTATTGATGAAATCCCCGCTTTAGGTATCGCTATGCTTTTTGCAAAAGGTAAAAGCGTGGTC
AAAAACGCTAAAGATTTACGATCTAAAGAAAGCGATAGGATCAAAGCGCTTATTTCTAACCTCAAAGCTTTAGGAATTGA
ATGCGAAGAATTTGAAGACGGATTTTATATAGAGGGATTAGAAGATATAAGCCAGTTAAAGCAGCGCTTTTCTCAAATTA
AACCCCCTATTATTAAAAGCTTTAATGACCACAGGATCGCGATGAGTTTTGCTATTTTAACCTTAATGCTGCCTTTAGAA
ATTGATAATTTAGAATGTGCAAACATTTCTTTCCCGCAATTCAAGCGTTTGCTCAATTTATTTAAAAAAGGGAGTCTCCA
TGGAAATTAA

Upstream 100 bases:

>100_bases
CCTAAATGATGAAGAGGTCAATTTAGCCGTGCAAAGAGTACTAGAAATTTTAGAAAAAAATTTTAACGTCCGCCTCAAAG
GATAAGATAAAGGATAGTAT

Downstream 100 bases:

>100_bases
AATGGCTAAGGATTATGGTTTTTGTTTTGGTGTCAAAAGAGCGATACAGATCGCTGAAAAAAATCAAAATAGCCTGATTT
TTGGCTCGCTCATCCATAAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MIELDINASDKSLSHRAVIFSLLAKKPCFVRNFLMGGDCLSSLEIAQNLGARVENIAKNSFKITPPWALKEPRKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNSRPMKRIIEPLKAFGTKILGREDNHFAPLVILGSPLKACDYESPIASAQVKS
AFILSALQAQGTSTYRESELSRNHTEIMLKSLGANIKDQDGVLKISPLEKPLEAFDFKIANDPSSAFFFALACAILPKSR
LLLKNVLLNPTRIEAFEVLKKMGTHIECVIKSKDLEIIGDIYIEHALLKAITIDQNIASLIDEIPALGIAMLFAKGKSVV
KNAKDLRSKESDRIKALISNLKALGIECEEFEDGFYIEGLEDISQLKQRFSQIKPPIIKSFNDHRIAMSFAILTLMLPLE
IDNLECANISFPQFKRLLNLFKKGSLHGN

Sequences:

>Translated_429_residues
MIELDINASDKSLSHRAVIFSLLAKKPCFVRNFLMGGDCLSSLEIAQNLGARVENIAKNSFKITPPWALKEPRKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNSRPMKRIIEPLKAFGTKILGREDNHFAPLVILGSPLKACDYESPIASAQVKS
AFILSALQAQGTSTYRESELSRNHTEIMLKSLGANIKDQDGVLKISPLEKPLEAFDFKIANDPSSAFFFALACAILPKSR
LLLKNVLLNPTRIEAFEVLKKMGTHIECVIKSKDLEIIGDIYIEHALLKAITIDQNIASLIDEIPALGIAMLFAKGKSVV
KNAKDLRSKESDRIKALISNLKALGIECEEFEDGFYIEGLEDISQLKQRFSQIKPPIIKSFNDHRIAMSFAILTLMLPLE
IDNLECANISFPQFKRLLNLFKKGSLHGN
>Mature_429_residues
MIELDINASDKSLSHRAVIFSLLAKKPCFVRNFLMGGDCLSSLEIAQNLGARVENIAKNSFKITPPWALKEPRKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNSRPMKRIIEPLKAFGTKILGREDNHFAPLVILGSPLKACDYESPIASAQVKS
AFILSALQAQGTSTYRESELSRNHTEIMLKSLGANIKDQDGVLKISPLEKPLEAFDFKIANDPSSAFFFALACAILPKSR
LLLKNVLLNPTRIEAFEVLKKMGTHIECVIKSKDLEIIGDIYIEHALLKAITIDQNIASLIDEIPALGIAMLFAKGKSVV
KNAKDLRSKESDRIKALISNLKALGIECEEFEDGFYIEGLEDISQLKQRFSQIKPPIIKSFNDHRIAMSFAILTLMLPLE
IDNLECANISFPQFKRLLNLFKKGSLHGN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=345, Percent_Identity=26.3768115942029, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=467, Percent_Identity=23.982869379015, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_HELAH (Q17YI6)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664289.1
- ProteinModelPortal:   Q17YI6
- SMR:   Q17YI6
- STRING:   Q17YI6
- GeneID:   4176932
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0459
- NMPDR:   fig|382638.8.peg.448
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   HACI382638:HAC_0459-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 47518; Mature: 47518

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELDINASDKSLSHRAVIFSLLAKKPCFVRNFLMGGDCLSSLEIAQNLGARVENIAKNS
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
FKITPPWALKEPRKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNSRPMKRIIEPLK
EEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AFGTKILGREDNHFAPLVILGSPLKACDYESPIASAQVKSAFILSALQAQGTSTYRESEL
HHHHHHCCCCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SRNHTEIMLKSLGANIKDQDGVLKISPLEKPLEAFDFKIANDPSSAFFFALACAILPKSR
HCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCEECCCCCHHHHHHHHHHHCCHHH
LLLKNVLLNPTRIEAFEVLKKMGTHIECVIKSKDLEIIGDIYIEHALLKAITIDQNIASL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHH
IDEIPALGIAMLFAKGKSVVKNAKDLRSKESDRIKALISNLKALGIECEEFEDGFYIEGL
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCEECCH
EDISQLKQRFSQIKPPIIKSFNDHRIAMSFAILTLMLPLEIDNLECANISFPQFKRLLNL
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCEECCCCCCCCCCHHHHHHHHH
FKKGSLHGN
HHCCCCCCC
>Mature Secondary Structure
MIELDINASDKSLSHRAVIFSLLAKKPCFVRNFLMGGDCLSSLEIAQNLGARVENIAKNS
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
FKITPPWALKEPRKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNSRPMKRIIEPLK
EEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AFGTKILGREDNHFAPLVILGSPLKACDYESPIASAQVKSAFILSALQAQGTSTYRESEL
HHHHHHCCCCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SRNHTEIMLKSLGANIKDQDGVLKISPLEKPLEAFDFKIANDPSSAFFFALACAILPKSR
HCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCEECCCCCHHHHHHHHHHHCCHHH
LLLKNVLLNPTRIEAFEVLKKMGTHIECVIKSKDLEIIGDIYIEHALLKAITIDQNIASL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHH
IDEIPALGIAMLFAKGKSVVKNAKDLRSKESDRIKALISNLKALGIECEEFEDGFYIEGL
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCEECCH
EDISQLKQRFSQIKPPIIKSFNDHRIAMSFAILTLMLPLEIDNLECANISFPQFKRLLNL
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCEECCCCCCCCCCHHHHHHHHH
FKKGSLHGN
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA