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The map label for this gene is dcm [H]

Identifier: 109946897

GI number: 109946897

Start: 233955

End: 235211

Strand: Reverse

Name: dcm [H]

Synonym: Hac_0283

Alternate gene names: 109946897

Gene position: 235211-233955 (Counterclockwise)

Preceding gene: 109946898

Following gene: 109946895

Centisome position: 15.14

GC content: 33.49

Gene sequence:

>1257_bases
ATGGCATATAATGTTTGTGAATTTTTTGTGGGAGCTGGTGGTTCGCATTTAGGCTTTATCCAACAAGGTTTTAAAACGCT
CTATGTTAATGATATAGACAAAGATGCCCTAAAAACTTTACTTCATAACAATAAAGAATTAAAAGATGCAATTATAGATC
AAACAAGCATTACAGAAATTGACCCTAAAAAATTACAAACACAAATAAAACAAGAGATTGATGTTATTTTTGCTGGCATT
GTGTGCAAAAGTTTTTCCTTAGCTGGGGAGCGCTCACCCAACGATAAACGCAATTATTTTTACCGCTATTATTTGGATAT
CATCAAAACCCTAAGGCCAAAAATCAGCATTATAGAAAATGTAAAAGGCATGCTAAACGCTAAAATTTTGCCACAAAATT
TAGATCCTAAAATTTTACAAGAAGTGGATATTTTATATCAAGAGTTAGAAAATTATAAGGGCAAAAAAGCGGAGTTAAGA
AAAAAAAATTCTATCACTAAAGAATTTGAAAATTACGGCTTAAATTTACGCCAAAAAAAACAAGACTTGCAAAAGGAACT
CAATCATTTATTGCATGGTGTCATAGATGATATTTTAAAAATTTATGAAAACTTGGGCTATCGTGTAGAGTTTAAAGTCT
TAAACAGTGCATGGTATGGGAGTGCGACCAAAAGAGAAAGATTGATCATAGTGGCTATTAGAAACGATTTGCCCTTTAAT
TTTGCATTCCCTAAACCCACCCATTTAAACGATGAAATCAATACTAAGTTAGATTTCAAAGATTTACCGACAAGCTTTAA
AAAACCTTTTTTGATTAGAGACGCTCTTGATTTGATTGATTATTCCAACTCAGATGATACAGACAATTTGCCCATGCAAC
ACAACCCTAAAACAATTGAGCGCTTTAAATACATACAAGAAGGCAAAAATATCCAAGAATGCATTGAGAGTTTGCCTAAA
CATTTACAAATCTCTAAATTCTATTCTAGAGGCAATACCATGCGTTTAAAAATGGACGCCCTATCTCCTACTTTAGTGCC
AGGGCATAGTAATTTTCCATTACACCCAATAGAGCATAGAAGTATCACCATTAGAGAAGCGGCAAGCATTACCGGCTTCC
CTACTTCTTACAAATTTTTTGGCTCACACACCAAGCGTTGCGAACAAGTGGGTAACGCTGTGCCTATTGCTTTGTCAAGC
GCGATTGCTAAAGAAGTTAAAAAATTTTTAGATAGTTTAAAATCAAAAGCTATTTAA

Upstream 100 bases:

>100_bases
ATCTTTAACCCTTTTACTAGCAATAAAGAAAATTTTATTAAGCATATTGAAAAATATTCACTATACAATAAATATAAAGA
AAGATATGAGGAAATCTTAA

Downstream 100 bases:

>100_bases
ACGCCCAAAAAAACCCACTAAAATAACTTCTTAAATCCATATCTTAAAATAAAGTTTTTGACTAGTCTTTTTCTTTTGCT
CTACAATTCTTTGATGCGAT

Product: site-specific DNA-methyltransferase

Products: NA

Alternate protein names: M.SinI; Cytosine-specific methyltransferase SinI [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MAYNVCEFFVGAGGSHLGFIQQGFKTLYVNDIDKDALKTLLHNNKELKDAIIDQTSITEIDPKKLQTQIKQEIDVIFAGI
VCKSFSLAGERSPNDKRNYFYRYYLDIIKTLRPKISIIENVKGMLNAKILPQNLDPKILQEVDILYQELENYKGKKAELR
KKNSITKEFENYGLNLRQKKQDLQKELNHLLHGVIDDILKIYENLGYRVEFKVLNSAWYGSATKRERLIIVAIRNDLPFN
FAFPKPTHLNDEINTKLDFKDLPTSFKKPFLIRDALDLIDYSNSDDTDNLPMQHNPKTIERFKYIQEGKNIQECIESLPK
HLQISKFYSRGNTMRLKMDALSPTLVPGHSNFPLHPIEHRSITIREAASITGFPTSYKFFGSHTKRCEQVGNAVPIALSS
AIAKEVKKFLDSLKSKAI

Sequences:

>Translated_418_residues
MAYNVCEFFVGAGGSHLGFIQQGFKTLYVNDIDKDALKTLLHNNKELKDAIIDQTSITEIDPKKLQTQIKQEIDVIFAGI
VCKSFSLAGERSPNDKRNYFYRYYLDIIKTLRPKISIIENVKGMLNAKILPQNLDPKILQEVDILYQELENYKGKKAELR
KKNSITKEFENYGLNLRQKKQDLQKELNHLLHGVIDDILKIYENLGYRVEFKVLNSAWYGSATKRERLIIVAIRNDLPFN
FAFPKPTHLNDEINTKLDFKDLPTSFKKPFLIRDALDLIDYSNSDDTDNLPMQHNPKTIERFKYIQEGKNIQECIESLPK
HLQISKFYSRGNTMRLKMDALSPTLVPGHSNFPLHPIEHRSITIREAASITGFPTSYKFFGSHTKRCEQVGNAVPIALSS
AIAKEVKKFLDSLKSKAI
>Mature_417_residues
AYNVCEFFVGAGGSHLGFIQQGFKTLYVNDIDKDALKTLLHNNKELKDAIIDQTSITEIDPKKLQTQIKQEIDVIFAGIV
CKSFSLAGERSPNDKRNYFYRYYLDIIKTLRPKISIIENVKGMLNAKILPQNLDPKILQEVDILYQELENYKGKKAELRK
KNSITKEFENYGLNLRQKKQDLQKELNHLLHGVIDDILKIYENLGYRVEFKVLNSAWYGSATKRERLIIVAIRNDLPFNF
AFPKPTHLNDEINTKLDFKDLPTSFKKPFLIRDALDLIDYSNSDDTDNLPMQHNPKTIERFKYIQEGKNIQECIESLPKH
LQISKFYSRGNTMRLKMDALSPTLVPGHSNFPLHPIEHRSITIREAASITGFPTSYKFFGSHTKRCEQVGNAVPIALSSA
IAKEVKKFLDSLKSKAI

Specific function: This methylase recognizes the double-stranded sequence GGWCC, causes specific methylation on C-4 on both strands, and protects the DNA from cleavage by the SinI endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525
- InterPro:   IPR010093 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 48045; Mature: 47914

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYNVCEFFVGAGGSHLGFIQQGFKTLYVNDIDKDALKTLLHNNKELKDAIIDQTSITEI
CCCCHHHHHHCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCCC
DPKKLQTQIKQEIDVIFAGIVCKSFSLAGERSPNDKRNYFYRYYLDIIKTLRPKISIIEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHH
VKGMLNAKILPQNLDPKILQEVDILYQELENYKGKKAELRKKNSITKEFENYGLNLRQKK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
QDLQKELNHLLHGVIDDILKIYENLGYRVEFKVLNSAWYGSATKRERLIIVAIRNDLPFN
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHCCCCCCCCCEEEEEEECCCCCE
FAFPKPTHLNDEINTKLDFKDLPTSFKKPFLIRDALDLIDYSNSDDTDNLPMQHNPKTIE
ECCCCCCCCCCCCCCEECHHHCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
RFKYIQEGKNIQECIESLPKHLQISKFYSRGNTMRLKMDALSPTLVPGHSNFPLHPIEHR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCCCCCCCC
SITIREAASITGFPTSYKFFGSHTKRCEQVGNAVPIALSSAIAKEVKKFLDSLKSKAI
CEEEEHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYNVCEFFVGAGGSHLGFIQQGFKTLYVNDIDKDALKTLLHNNKELKDAIIDQTSITEI
CCCHHHHHHCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCCCC
DPKKLQTQIKQEIDVIFAGIVCKSFSLAGERSPNDKRNYFYRYYLDIIKTLRPKISIIEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHH
VKGMLNAKILPQNLDPKILQEVDILYQELENYKGKKAELRKKNSITKEFENYGLNLRQKK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
QDLQKELNHLLHGVIDDILKIYENLGYRVEFKVLNSAWYGSATKRERLIIVAIRNDLPFN
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHCCCCCCCCCEEEEEEECCCCCE
FAFPKPTHLNDEINTKLDFKDLPTSFKKPFLIRDALDLIDYSNSDDTDNLPMQHNPKTIE
ECCCCCCCCCCCCCCEECHHHCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
RFKYIQEGKNIQECIESLPKHLQISKFYSRGNTMRLKMDALSPTLVPGHSNFPLHPIEHR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCCCCCCCC
SITIREAASITGFPTSYKFFGSHTKRCEQVGNAVPIALSSAIAKEVKKFLDSLKSKAI
CEEEEHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2836359 [H]