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The map label for this gene is selA [H]

Identifier: 109946703

GI number: 109946703

Start: 68449

End: 69627

Strand: Reverse

Name: selA [H]

Synonym: Hac_0070

Alternate gene names: 109946703

Gene position: 69627-68449 (Counterclockwise)

Preceding gene: 109946704

Following gene: 109946702

Centisome position: 4.48

GC content: 35.54

Gene sequence:

>1179_bases
ATGGCTAATATCACGACTAAAGAAACGCCCCAAATAATCTCCGATCTCTTGAAAAACCCTTACCAAAAGATCATCAATGC
GAGTGCGAGCGTTTTTGATGAAAGCCATGGGCGATCGTTTTTTAGCCAAAAATTTTATGAAAGGATTGAACCTTGCTTAA
AAGAAATCTTAACCCACCCCATTGATTTGGAATGCGATCTAAACACCGCCAAAAAAACCAACCGCTTAACCCCCTTAAAA
AAGCTTTTTAAAGCGTGTTTTGACACTGAAGAAATTTTGATTGTCAATAATAACACAAGCGCTTTAATTCTTATTGCTAA
CGCTTTAGCCTTGCAACAAGAAATCATTGTTTCTTATGGCGAATTAGTGGGCATGGGAGGGAATTTTAAGATTAAAGACA
TTTTGTTAGCCAGTGGGGCTAGGTTGCATTTAGTGGGAAATACCAATCGCACTTATTTAAGGGATTACCGCTTAGCCTTG
AATGAAAATAGTAAAATGCTATTTAAAATCCATAACCCCACTTTTAAAAAAGACACGCCTTTTAAAGATTTGCAAGCCCT
AGCTAAAGAGCATGGTTTGATAGATTATTACAATTTAGGGGATGTGGATCTATTCAATAAAAGGGCTTTGGAAGAAATTT
TAGCCCTAAAACCATCGCTTTTAAGCTTTAGTGCAGATAAGTTCTTTAATGGCGTGCAAGCTGGCATTATTATGGGGCAA
AAAGAATTGATTGAGACCTTAAAAAACCACCCCCTTTATAGAGCTTTGAGAACGGATAAAATCACGCTCACTTTACTTTT
CCATAGCCTAAAAGCATGGATAAGCCATAAAGAAGAGATTAAATTCTATGAATTACTCAATCAAACTAAAGACGAATTGT
TACAAAAAGCTTTAAAACTCTACGCTCTTTTAAAACCTTTAGAATTAGATGTGAGCATAGCGTCTAGCTTTTCTAAAATA
GGGAATTTGTCCCATACAGAATTAGAATCCTTTTGCGTGAAGATCCGGTCTAAAAACACCCAGATTTTAGATTGTGAGAA
GCTTTATTTAAGACTTTTTCAAAAAGGCGTTATTTCAAGAATCTCATGCGAATTTGTGTGTTTTGAAGTCTTTAGCTTGG
ATGGAGAAGATTTGGAAAAAATCGCTCTAGTTTTAGAAGAAATCCTTAATAAGGCTTAA

Upstream 100 bases:

>100_bases
AAGGATTTTAAAAAAGTAGTTTTATTAAAAATTTAGCGAGCTTGAATTAAAATCGTGCCTTATTAACTCTCAAAAAGGAA
AAGCAAACGCGCTTTCATCT

Downstream 100 bases:

>100_bases
AAATTCGCTATAATAGAATCTCTTTTAAAATACTCTCTCCTACAAAAATTTAAAGGAACTCAAAAATGGAAAAAATCAGC
GACCTTATAGAATGCATTGC

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MANITTKETPQIISDLLKNPYQKIINASASVFDESHGRSFFSQKFYERIEPCLKEILTHPIDLECDLNTAKKTNRLTPLK
KLFKACFDTEEILIVNNNTSALILIANALALQQEIIVSYGELVGMGGNFKIKDILLASGARLHLVGNTNRTYLRDYRLAL
NENSKMLFKIHNPTFKKDTPFKDLQALAKEHGLIDYYNLGDVDLFNKRALEEILALKPSLLSFSADKFFNGVQAGIIMGQ
KELIETLKNHPLYRALRTDKITLTLLFHSLKAWISHKEEIKFYELLNQTKDELLQKALKLYALLKPLELDVSIASSFSKI
GNLSHTELESFCVKIRSKNTQILDCEKLYLRLFQKGVISRISCEFVCFEVFSLDGEDLEKIALVLEEILNKA

Sequences:

>Translated_392_residues
MANITTKETPQIISDLLKNPYQKIINASASVFDESHGRSFFSQKFYERIEPCLKEILTHPIDLECDLNTAKKTNRLTPLK
KLFKACFDTEEILIVNNNTSALILIANALALQQEIIVSYGELVGMGGNFKIKDILLASGARLHLVGNTNRTYLRDYRLAL
NENSKMLFKIHNPTFKKDTPFKDLQALAKEHGLIDYYNLGDVDLFNKRALEEILALKPSLLSFSADKFFNGVQAGIIMGQ
KELIETLKNHPLYRALRTDKITLTLLFHSLKAWISHKEEIKFYELLNQTKDELLQKALKLYALLKPLELDVSIASSFSKI
GNLSHTELESFCVKIRSKNTQILDCEKLYLRLFQKGVISRISCEFVCFEVFSLDGEDLEKIALVLEEILNKA
>Mature_391_residues
ANITTKETPQIISDLLKNPYQKIINASASVFDESHGRSFFSQKFYERIEPCLKEILTHPIDLECDLNTAKKTNRLTPLKK
LFKACFDTEEILIVNNNTSALILIANALALQQEIIVSYGELVGMGGNFKIKDILLASGARLHLVGNTNRTYLRDYRLALN
ENSKMLFKIHNPTFKKDTPFKDLQALAKEHGLIDYYNLGDVDLFNKRALEEILALKPSLLSFSADKFFNGVQAGIIMGQK
ELIETLKNHPLYRALRTDKITLTLLFHSLKAWISHKEEIKFYELLNQTKDELLQKALKLYALLKPLELDVSIASSFSKIG
NLSHTELESFCVKIRSKNTQILDCEKLYLRLFQKGVISRISCEFVCFEVFSLDGEDLEKIALVLEEILNKA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=322, Percent_Identity=35.7142857142857, Blast_Score=161, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 44684; Mature: 44552

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANITTKETPQIISDLLKNPYQKIINASASVFDESHGRSFFSQKFYERIEPCLKEILTHP
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
IDLECDLNTAKKTNRLTPLKKLFKACFDTEEILIVNNNTSALILIANALALQQEIIVSYG
CCEEECCCHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHH
ELVGMGGNFKIKDILLASGARLHLVGNTNRTYLRDYRLALNENSKMLFKIHNPTFKKDTP
HHCCCCCCEEEHHHHEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
FKDLQALAKEHGLIDYYNLGDVDLFNKRALEEILALKPSLLSFSADKFFNGVQAGIIMGQ
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHCHHHHHHHCCH
KELIETLKNHPLYRALRTDKITLTLLFHSLKAWISHKEEIKFYELLNQTKDELLQKALKL
HHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YALLKPLELDVSIASSFSKIGNLSHTELESFCVKIRSKNTQILDCEKLYLRLFQKGVISR
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHH
ISCEFVCFEVFSLDGEDLEKIALVLEEILNKA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANITTKETPQIISDLLKNPYQKIINASASVFDESHGRSFFSQKFYERIEPCLKEILTHP
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
IDLECDLNTAKKTNRLTPLKKLFKACFDTEEILIVNNNTSALILIANALALQQEIIVSYG
CCEEECCCHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHH
ELVGMGGNFKIKDILLASGARLHLVGNTNRTYLRDYRLALNENSKMLFKIHNPTFKKDTP
HHCCCCCCEEEHHHHEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
FKDLQALAKEHGLIDYYNLGDVDLFNKRALEEILALKPSLLSFSADKFFNGVQAGIIMGQ
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHCHHHHHHHCCH
KELIETLKNHPLYRALRTDKITLTLLFHSLKAWISHKEEIKFYELLNQTKDELLQKALKL
HHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YALLKPLELDVSIASSFSKIGNLSHTELESFCVKIRSKNTQILDCEKLYLRLFQKGVISR
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHH
ISCEFVCFEVFSLDGEDLEKIALVLEEILNKA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA