Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 109946646

GI number: 109946646

Start: 5021

End: 6886

Strand: Direct

Name: recG [H]

Synonym: Hac_0006

Alternate gene names: 109946646

Gene position: 5021-6886 (Clockwise)

Preceding gene: 109946643

Following gene: 109946647

Centisome position: 0.32

GC content: 36.17

Gene sequence:

>1866_bases
TTGCAAGAAATAAATCATTTATTAAAAACATTGAATGTGAAATCGCTTTTAGAAGCCTTGCTTGTTTATACGCCTAAGGG
TTATAAAGATTTAAGCTTGTTAGAGCGTTTTGAAATGGGTTTGAGCGGCGTTTTAGAAGTGGATGTTTTAGATAAAAAAA
ACTATGCCAAAGTTTTAAAGATTTTTGCTTATTCCAAACAATTTTGCAAAAATTTAGAGCTTGTCTTTTTCAATTACAGC
GCGTTCCATTACAACCAATTTAAAATCGGCGAGAGTTTATTGATTTATGGTAAATTAGAGCAAAGCTCTTTTAATCAAGC
TTATATTATTAACACGCCTAAAATCCTTAAAGAATTTGGCGGCATTTCTTTGCTTTTTAAAAAAGCCAAAAACCATAAAA
AAATCCAAGAAAATTTGCAAAAACTCATTTCTTTAGAAAATCTAAAAAATGAAGGTATTAAAGAAAATATCGCGCATCTG
TTATTAGAAATCTTTTTCCCCACTCCACATTTTCTCAAAGATTATGAATACTATAAAACTTTCCCTTCACAGCATTTAAA
TGCATTAAAATATATTGAAATGCTTTTTTATATGAAAAATTTAGAGCGTAAAAAATTGCAATTCAACGCTAAAATCATAT
GCCCCAATAATAGCGAGCGCTTAAATCATTTCATCGCTTCTTTACCCTTTAAACTCACTAACGACCAACAAAACGCCATT
AAAGAAATCCAAAACGATCTCACTAGCCCTATAGCGTGTAAGCGTTTGATTGTAGGCGATGTGGGGTGCGGGAAAACGAT
GGTGATTTTAGCGAGCATGGTATTAGCTTATCCTAATAAAACCCTTTTAATGGCGCCCACTTCCATTCTCGCTAAACAGC
TTTATAACGAAGCCTTAAAATTTTTACCCCCTTATTTTGAAGTGGAATTATTGCTAGGCGGGAGTCATAAAAAAAATCAT
TTATTTGAAAAAATCACTCATGTTGTTATAGGCACGCAAGCGTTGTTATTTGATAAGCGCGATTTAGATGAATTTGCTCT
GGTGATCACTGATGAGCAGCACAGGTTTGGCACAAAACAGCGCTACCAATTAGAAAAAATGGCGAGCAGTAAGGGCAATA
AACCCCATTCCTTGCAATTTTCCGCAACCCCCATTCCTCGCACTCTAGCTCTAGCCAAAAGCGCGTTTGTCCAAACGACT
ATGATTAGAGGAATCCCCTACCCTAAAGAGATTAAAACTCTGGTTTTGCATAAAAGGGAATTTAAATTAGTTATGGAGAA
AATTAGCGAAGAAATCGCTAAAAACCATCAAGTCATTGTCGTTTATCCTCTTGTGAATGAGAGCGAAAAAATCCCCTATT
TATCGCTGAGTGAGGGGGCAAGCTTTTGGCAAAAACGCTTTAAAAATGTTTATATCACTTCAGGGCAAGATAAAAATAAA
GAAGAGGTGATTGAAGAATTTAGAGAGTCAGGGAGTATTCTTTTAGCGACCACGCTCATTGAAGTGGGCATTTCTTTACC
GCGATTGAGCGTGATGGTGGTTTTAGCGCCTGAAAGGTTAGGCTTAGCGACCTTGCACCAATTAAGGGGGCGTGTGTCTC
GTAATGGTTTGAAAGGCTATTGTTTTTTATGCACGATTCAAGAAGAAAACGAACGATTAGAAAAGTTTGCTGAGGAATTA
GACGGGTTTAAGATCGCTGAATTGGATTTAGAATACAGAAAGAGCGGAGATTTACTCCAGGGTGGGGAGCAGAGCGGGAA
TAGCTTTGAATACATTGATTTGGCTAAAGATGAAAGCATTATCGCTGAAGTGAAACAGGATTTTTTAAAAAATGTCAGTG
TTTCACAAGGAACATTGAACATTTGA

Upstream 100 bases:

>100_bases
TAATGTATAATTTGATTATCTTATCACAAAATGGTTAAAATACTAGGATAAAACTAATAAGGTTAAGGCTTTTTATGGGA
TTAGCTAGGGTAAGAACAAA

Downstream 100 bases:

>100_bases
AAATTAAGGTGGAATTGGGTAATTTAAATCATTTAAAATAAAGGACAGAGATGCAAAATAAAGAGATTTGTGAAGAAGAA
AGCGTTAATGAAAAAAATTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MQEINHLLKTLNVKSLLEALLVYTPKGYKDLSLLERFEMGLSGVLEVDVLDKKNYAKVLKIFAYSKQFCKNLELVFFNYS
AFHYNQFKIGESLLIYGKLEQSSFNQAYIINTPKILKEFGGISLLFKKAKNHKKIQENLQKLISLENLKNEGIKENIAHL
LLEIFFPTPHFLKDYEYYKTFPSQHLNALKYIEMLFYMKNLERKKLQFNAKIICPNNSERLNHFIASLPFKLTNDQQNAI
KEIQNDLTSPIACKRLIVGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSHKKNH
LFEKITHVVIGTQALLFDKRDLDEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVQTT
MIRGIPYPKEIKTLVLHKREFKLVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYITSGQDKNK
EEVIEEFRESGSILLATTLIEVGISLPRLSVMVVLAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAEEL
DGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDESIIAEVKQDFLKNVSVSQGTLNI

Sequences:

>Translated_621_residues
MQEINHLLKTLNVKSLLEALLVYTPKGYKDLSLLERFEMGLSGVLEVDVLDKKNYAKVLKIFAYSKQFCKNLELVFFNYS
AFHYNQFKIGESLLIYGKLEQSSFNQAYIINTPKILKEFGGISLLFKKAKNHKKIQENLQKLISLENLKNEGIKENIAHL
LLEIFFPTPHFLKDYEYYKTFPSQHLNALKYIEMLFYMKNLERKKLQFNAKIICPNNSERLNHFIASLPFKLTNDQQNAI
KEIQNDLTSPIACKRLIVGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSHKKNH
LFEKITHVVIGTQALLFDKRDLDEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVQTT
MIRGIPYPKEIKTLVLHKREFKLVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYITSGQDKNK
EEVIEEFRESGSILLATTLIEVGISLPRLSVMVVLAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAEEL
DGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDESIIAEVKQDFLKNVSVSQGTLNI
>Mature_621_residues
MQEINHLLKTLNVKSLLEALLVYTPKGYKDLSLLERFEMGLSGVLEVDVLDKKNYAKVLKIFAYSKQFCKNLELVFFNYS
AFHYNQFKIGESLLIYGKLEQSSFNQAYIINTPKILKEFGGISLLFKKAKNHKKIQENLQKLISLENLKNEGIKENIAHL
LLEIFFPTPHFLKDYEYYKTFPSQHLNALKYIEMLFYMKNLERKKLQFNAKIICPNNSERLNHFIASLPFKLTNDQQNAI
KEIQNDLTSPIACKRLIVGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSHKKNH
LFEKITHVVIGTQALLFDKRDLDEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVQTT
MIRGIPYPKEIKTLVLHKREFKLVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYITSGQDKNK
EEVIEEFRESGSILLATTLIEVGISLPRLSVMVVLAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAEEL
DGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDESIIAEVKQDFLKNVSVSQGTLNI

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=586, Percent_Identity=31.2286689419795, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787357, Length=396, Percent_Identity=32.3232323232323, Blast_Score=169, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 71117; Mature: 71117

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEINHLLKTLNVKSLLEALLVYTPKGYKDLSLLERFEMGLSGVLEVDVLDKKNYAKVLK
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
IFAYSKQFCKNLELVFFNYSAFHYNQFKIGESLLIYGKLEQSSFNQAYIINTPKILKEFG
HHHHHHHHHCCCEEEEEECCEEEECEEECCCEEEEEEEECCCCCCCEEEECCHHHHHHHC
GISLLFKKAKNHKKIQENLQKLISLENLKNEGIKENIAHLLLEIFFPTPHFLKDYEYYKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHC
FPSQHLNALKYIEMLFYMKNLERKKLQFNAKIICPNNSERLNHFIASLPFKLTNDQQNAI
CCHHHHHHHHHHHHHHHHHCCHHHHEEECEEEECCCCHHHHHHHHHHCCCEECCCHHHHH
KEIQNDLTSPIACKRLIVGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALK
HHHHHHCCCHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FLPPYFEVELLLGGSHKKNHLFEKITHVVIGTQALLFDKRDLDEFALVITDEQHRFGTKQ
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHCCCHH
RYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVQTTMIRGIPYPKEIKTLVLHKRE
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FKLVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYITSGQDKNK
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHCCEEEEECCCCCCH
EEVIEEFRESGSILLATTLIEVGISLPRLSVMVVLAPERLGLATLHQLRGRVSRNGLKGY
HHHHHHHHHCCCEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
CFLCTIQEENERLEKFAEELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDESI
EEEEEEECHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCCEEEEEECCCHHH
IAEVKQDFLKNVSVSQGTLNI
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQEINHLLKTLNVKSLLEALLVYTPKGYKDLSLLERFEMGLSGVLEVDVLDKKNYAKVLK
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
IFAYSKQFCKNLELVFFNYSAFHYNQFKIGESLLIYGKLEQSSFNQAYIINTPKILKEFG
HHHHHHHHHCCCEEEEEECCEEEECEEECCCEEEEEEEECCCCCCCEEEECCHHHHHHHC
GISLLFKKAKNHKKIQENLQKLISLENLKNEGIKENIAHLLLEIFFPTPHFLKDYEYYKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHC
FPSQHLNALKYIEMLFYMKNLERKKLQFNAKIICPNNSERLNHFIASLPFKLTNDQQNAI
CCHHHHHHHHHHHHHHHHHCCHHHHEEECEEEECCCCHHHHHHHHHHCCCEECCCHHHHH
KEIQNDLTSPIACKRLIVGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALK
HHHHHHCCCHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FLPPYFEVELLLGGSHKKNHLFEKITHVVIGTQALLFDKRDLDEFALVITDEQHRFGTKQ
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHCCCHH
RYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVQTTMIRGIPYPKEIKTLVLHKRE
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FKLVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYITSGQDKNK
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHCCEEEEECCCCCCH
EEVIEEFRESGSILLATTLIEVGISLPRLSVMVVLAPERLGLATLHQLRGRVSRNGLKGY
HHHHHHHHHCCCEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
CFLCTIQEENERLEKFAEELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDESI
EEEEEEECHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCCEEEEEECCCHHH
IAEVKQDFLKNVSVSQGTLNI
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]