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The map label for this gene is dcuB [H]

Identifier: 108810976

GI number: 108810976

Start: 940255

End: 940935

Strand: Reverse

Name: dcuB [H]

Synonym: YPN_0811

Alternate gene names: 108810976

Gene position: 940935-940255 (Counterclockwise)

Preceding gene: 108810977

Following gene: 108810975

Centisome position: 20.75

GC content: 44.64

Gene sequence:

>681_bases
ATGATAACTCTACAATTTATAATTATAATTCTATGTTTGCTGTTAGGTACGCGTTACGGAGGGATGGGGCTGGGGTTAAT
AAGTGGTATCGGCTTATTTATTCTGACCTTTATCTTTGGCCTCGAACCAGGAAAACCACCTGTAGATGTAATGCTAACAA
TATTAGCGGTTATTGGTTGTGCTTCAGTACTACAAACCGCAGGCGGGTTAAATGTAATGATGCAATTTGCCGAGCGATTA
TTACGCCGCCACCCACAGCACATTACGTTATTAGCGCCCTTCACGACGTGGTCATTAACCTTTCTTTGCGGCACCGGACA
TGTCGTTTACACCATGTTCCCCATAATTTCCGACATCGCCATTAAAAAAGGTATTCGTCCAGAACGACCAATGGCGGTTG
CATCCGTTGCCTCACAGATGGCAATTACGGCATCTCCAGTATCGGTTGCTGTCGTATCATTAGTTTCAATTATTGGTGCT
AACCATGGCATCGGCCATGCCTATAGCATTCTGGAAATTCTGGCTATTTCAGTTCCCGCCTCTTTGGTTGGAGTGCTAAT
CGCCGCCCTGTGGAGCCTGCGCCGTGGTAAAGATCTGGATAAAGATCCTGATTTTCAGAAAAAAATAAAAGATCCAGAGC
AGCGGGCCTATATATATATGGCTCAACAGATACGTTACTGA

Upstream 100 bases:

>100_bases
TCTGTGCTCTGATAAGAGAAATCGAGTAAGGATTATAGTCATCGAATAAAACCAACAAATACATAACCGAATTTCATTCA
TATTTGAAGCGAGGGACATC

Downstream 100 bases:

>100_bases
ATCAGGTTTTTCCAAAACAAGCTTATTGGTCAACTTGGATATTCTTTGCCGCTATCGTCATTGTCGTCTTGTTGGGCGCT
TTTGCAGACCTGCGCCCTGC

Product: hypothetical protein

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGCASVLQTAGGLNVMMQFAERL
LRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIAIKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGA
NHGIGHAYSILEILAISVPASLVGVLIAALWSLRRGKDLDKDPDFQKKIKDPEQRAYIYMAQQIRY

Sequences:

>Translated_226_residues
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGCASVLQTAGGLNVMMQFAERL
LRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIAIKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGA
NHGIGHAYSILEILAISVPASLVGVLIAALWSLRRGKDLDKDPDFQKKIKDPEQRAYIYMAQQIRY
>Mature_226_residues
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGCASVLQTAGGLNVMMQFAERL
LRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIAIKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGA
NHGIGHAYSILEILAISVPASLVGVLIAALWSLRRGKDLDKDPDFQKKIKDPEQRAYIYMAQQIRY

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=183, Percent_Identity=57.9234972677596, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1790580, Length=212, Percent_Identity=39.1509433962264, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 24473; Mature: 24473

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGC
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ASVLQTAGGLNVMMQFAERLLRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIA
HHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHH
IKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGANHGIGHAYSILEILAISVPA
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
SLVGVLIAALWSLRRGKDLDKDPDFQKKIKDPEQRAYIYMAQQIRY
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITLQFIIIILCLLLGTRYGGMGLGLISGIGLFILTFIFGLEPGKPPVDVMLTILAVIGC
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ASVLQTAGGLNVMMQFAERLLRRHPQHITLLAPFTTWSLTFLCGTGHVVYTMFPIISDIA
HHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHH
IKKGIRPERPMAVASVASQMAITASPVSVAVVSLVSIIGANHGIGHAYSILEILAISVPA
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
SLVGVLIAALWSLRRGKDLDKDPDFQKKIKDPEQRAYIYMAQQIRY
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]