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The map label for this gene is dhmA [H]

Identifier: 108801912

GI number: 108801912

Start: 5240493

End: 5241407

Strand: Reverse

Name: dhmA [H]

Synonym: Mmcs_4949

Alternate gene names: 108801912

Gene position: 5241407-5240493 (Counterclockwise)

Preceding gene: 108801915

Following gene: 108801911

Centisome position: 91.87

GC content: 70.27

Gene sequence:

>915_bases
ATGCAGACGCTGCGCACCCCGGACGAACGGTTTCTGGCTCTGCCCGACTTCCCTTATCCGCCAGGTTATTCCGACATCGA
CGACGGTGACGGTGGCCGGCTGCGGGTGGCCTGGGTGCAGGATGGGCCTGCCGACGGCGAACCGGTGTTGATGCTGCACG
GCGAGCCGTCGTGGTCGTTCCTGTACCGCAAGATGATCCCGATCCTGGCGGGCGCGGGGTTCCGCGTCGTCTGCCCCGAC
CTCGTCGGGTTCGGCCGTTCCGACAAGCCCACGCGCGTCGAGGACCACACCTACGCCCGCCACGTCGAGTGGATGCGCAC
GCTCGCGTTCGATGTGCTCGACCTGCGCGGGGTGACGCTGGTGGGGCAGGACTGGGGTGGGCTGATCGGGCTGCGGTTGG
CCGCCGAACACCCCGACCGGTTCGCCCGCATCGTCGTCGCGAACACCGGGCTGCCGACCGGGGATTTCCCGATGCCCGAC
ATCTGGTGGCAATTCCGCAACGCGATCCAGACTGTGGACGATCTCGACGTGGGGCGATGGGTTCAGGCCGGATGTGCTCA
TCCGATGTCCGACGAGGTGCGCGCCGCCTACGACGCCCCGTTCCCCGACGACTCCTACTGCGCAGGCCCCCGCGCGATGC
CGCTGCTTGTGCCCACCACGCCCGAGGACCCGGCGTCGGCGGCGAACCGCGCGGCGTGGGCGGCGCTGTCCGCCAGCGAC
ACCCCGATGCTCGTCGCGTTCAGCGACAGCGATCCGATCACCGGCGCGATGGCGCCGATCTTCGCCCGCGAGATGCGCGG
CGCCGCGGGCATCGACCACCCGACGATCCGCGAAGCGGGACACTTCCTGCAGGAGGACGCGGGCGAGGACCTCGCCCGGG
CGGTCGTCGAGTTCTGCCGCAGGCGGTCCTGTTGA

Upstream 100 bases:

>100_bases
CGTCAATGCCGGGGCCGTCCCGAGCAGTATCGGTGTGCGGGCCTCCGCCGATCATGATAATCGGGAAAATCCGCTTGCCG
ACGCGAGTAAGTTCGCGGTC

Downstream 100 bases:

>100_bases
ATACCTGACGTGGATCAGCAGTTCTTCACCGTCGAGGCCGAGCTGCCCGGGCGACGCGGCCGGGCCGGGGTGATCCGCAC
CCCGCACGGGGAGATCCGCA

Product: haloalkane dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MQTLRTPDERFLALPDFPYPPGYSDIDDGDGGRLRVAWVQDGPADGEPVLMLHGEPSWSFLYRKMIPILAGAGFRVVCPD
LVGFGRSDKPTRVEDHTYARHVEWMRTLAFDVLDLRGVTLVGQDWGGLIGLRLAAEHPDRFARIVVANTGLPTGDFPMPD
IWWQFRNAIQTVDDLDVGRWVQAGCAHPMSDEVRAAYDAPFPDDSYCAGPRAMPLLVPTTPEDPASAANRAAWAALSASD
TPMLVAFSDSDPITGAMAPIFAREMRGAAGIDHPTIREAGHFLQEDAGEDLARAVVEFCRRRSC

Sequences:

>Translated_304_residues
MQTLRTPDERFLALPDFPYPPGYSDIDDGDGGRLRVAWVQDGPADGEPVLMLHGEPSWSFLYRKMIPILAGAGFRVVCPD
LVGFGRSDKPTRVEDHTYARHVEWMRTLAFDVLDLRGVTLVGQDWGGLIGLRLAAEHPDRFARIVVANTGLPTGDFPMPD
IWWQFRNAIQTVDDLDVGRWVQAGCAHPMSDEVRAAYDAPFPDDSYCAGPRAMPLLVPTTPEDPASAANRAAWAALSASD
TPMLVAFSDSDPITGAMAPIFAREMRGAAGIDHPTIREAGHFLQEDAGEDLARAVVEFCRRRSC
>Mature_304_residues
MQTLRTPDERFLALPDFPYPPGYSDIDDGDGGRLRVAWVQDGPADGEPVLMLHGEPSWSFLYRKMIPILAGAGFRVVCPD
LVGFGRSDKPTRVEDHTYARHVEWMRTLAFDVLDLRGVTLVGQDWGGLIGLRLAAEHPDRFARIVVANTGLPTGDFPMPD
IWWQFRNAIQTVDDLDVGRWVQAGCAHPMSDEVRAAYDAPFPDDSYCAGPRAMPLLVPTTPEDPASAANRAAWAALSASD
TPMLVAFSDSDPITGAMAPIFAREMRGAAGIDHPTIREAGHFLQEDAGEDLARAVVEFCRRRSC

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=117, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562298, Length=135, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324392, Length=127, Percent_Identity=33.0708661417323, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33376; Mature: 33376

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLRTPDERFLALPDFPYPPGYSDIDDGDGGRLRVAWVQDGPADGEPVLMLHGEPSWSF
CCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHH
LYRKMIPILAGAGFRVVCPDLVGFGRSDKPTRVEDHTYARHVEWMRTLAFDVLDLRGVTL
HHHHHHHHHHCCCCEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
VGQDWGGLIGLRLAAEHPDRFARIVVANTGLPTGDFPMPDIWWQFRNAIQTVDDLDVGRW
ECCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHH
VQAGCAHPMSDEVRAAYDAPFPDDSYCAGPRAMPLLVPTTPEDPASAANRAAWAALSASD
HHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHEEEECCCC
TPMLVAFSDSDPITGAMAPIFAREMRGAAGIDHPTIREAGHFLQEDAGEDLARAVVEFCR
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RRSC
HCCC
>Mature Secondary Structure
MQTLRTPDERFLALPDFPYPPGYSDIDDGDGGRLRVAWVQDGPADGEPVLMLHGEPSWSF
CCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHH
LYRKMIPILAGAGFRVVCPDLVGFGRSDKPTRVEDHTYARHVEWMRTLAFDVLDLRGVTL
HHHHHHHHHHCCCCEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEE
VGQDWGGLIGLRLAAEHPDRFARIVVANTGLPTGDFPMPDIWWQFRNAIQTVDDLDVGRW
ECCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHH
VQAGCAHPMSDEVRAAYDAPFPDDSYCAGPRAMPLLVPTTPEDPASAANRAAWAALSASD
HHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHEEEECCCC
TPMLVAFSDSDPITGAMAPIFAREMRGAAGIDHPTIREAGHFLQEDAGEDLARAVVEFCR
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RRSC
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA