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The map label for this gene is acdA [H]

Identifier: 108801361

GI number: 108801361

Start: 4676798

End: 4677958

Strand: Reverse

Name: acdA [H]

Synonym: Mmcs_4398

Alternate gene names: 108801361

Gene position: 4677958-4676798 (Counterclockwise)

Preceding gene: 108801362

Following gene: 108801360

Centisome position: 81.99

GC content: 69.08

Gene sequence:

>1161_bases
GTGAGCATCGACGACTTCCGCGCCACCGTGCGGGCGTGGTGTGCCGAACACGTGCCGTCGGACTGGCGCGAGAAGCAGAC
CGGCGTGGGCGACGAGGAGTTCGTCCGCTTCCAGAAGGCCTGGTTCGCCGAACTGCACAGCGCCGGCTACGCGGTCCCGC
ACTGGCCCGCCGAATGGGGTGGCGGGCTGTCGGTGGCCGAGCAGATCGTGCTGTACCAGGAGTTGGCCGCCCACGACGCG
CCGCGCCTGGTGCTGGCGTTCGTCGGTATCCACCACGCCGCGTCGACGCTGCTGGTGGCCGGCACCGACGAGCAGCGGCG
CAGGCACCTGCCTGCGATCCTCGACGGCGAGATCTGGGTGCAGGGTTTCTCCGAACCCGAAGCCGGATCCGATCTGGCGA
GCCTGCGCACCACCGCGCACCGCACCGGCGACACGTTCGTCGTCAACGGCCAAAAGCTCTGGGCCAGTGGCGGTATGCAC
GCCGACTGGTGTCTGCTGCTGGCCCGCACCGACCCGGATGCACCGAAGCGTAAAGGCATCTCGTACTTCCTGCTCGACAT
GACGACCCCGGGCGTCGACGTGCGGCCGATCCGCAACGCCGTCGGCGACTCCCACTTCTGCGAGATCTTCCTCAACGACG
TCGAGATCCCGGCCGCCAATCTGGTGGGCGCCGAGAACGCGGGCTGGCAGGTCGCGCAGGAGACCCTCGGCGCCGAGCGG
GGGATGACCATGCTCGAACTGGCCGAGCGCCTGGCCAACGCCGGCTTCCGCCGACTCGTGCGGACCAGCCCGGTCGACGA
TCCCGTGGTGGCGGATCGGTTGGCGCAGTTCGAATGCGAGATCACCGCGCTGCGCGGGCTCTGCCGAAAGGTGGTGGAGG
GCCACGACTCCGGTGCGATCGGACCGGCCGACGCGTCGATCGTGAAGCTCTATTACAGCGAACTGCTGCAGCGGCTCACC
GACTTCGGCGCCGAGATCGGCGGTCCGGCCGGCCATACCGAGATCGCCAAACCGATGTCGAGCGGGTGGGAGTCCGGGTC
GTGGGTGCTCGACTTCATCGGCTCCTGGGAGTGGACGATCCCCGGCGGTTCGAGCGAGATCCAGCGCACCATCATCGGTG
AGCGCGGCCTCGGCCTGCCCCGAGAACCGAGCGCAGTCTGA

Upstream 100 bases:

>100_bases
CCATGGCCGGACCGCTGCAGGCCGGGTTCGCCGCCGAGGTCGCCACCATGCGCTCCGAGGACCACCGGCGCAGGCTGCTC
GCGTTCCGGGAGGGTGCGAC

Downstream 100 bases:

>100_bases
TGGGCTTCGAGGAGTTCCATGACGAGTTGCGGTCCGTCGCGGCCGACGTGCTGGACAAAGGGCGCGAGGTGGACTGGCCC
GTACTCGTCGACGCAGGGTG

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSIDDFRATVRAWCAEHVPSDWREKQTGVGDEEFVRFQKAWFAELHSAGYAVPHWPAEWGGGLSVAEQIVLYQELAAHDA
PRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGEIWVQGFSEPEAGSDLASLRTTAHRTGDTFVVNGQKLWASGGMH
ADWCLLLARTDPDAPKRKGISYFLLDMTTPGVDVRPIRNAVGDSHFCEIFLNDVEIPAANLVGAENAGWQVAQETLGAER
GMTMLELAERLANAGFRRLVRTSPVDDPVVADRLAQFECEITALRGLCRKVVEGHDSGAIGPADASIVKLYYSELLQRLT
DFGAEIGGPAGHTEIAKPMSSGWESGSWVLDFIGSWEWTIPGGSSEIQRTIIGERGLGLPREPSAV

Sequences:

>Translated_386_residues
MSIDDFRATVRAWCAEHVPSDWREKQTGVGDEEFVRFQKAWFAELHSAGYAVPHWPAEWGGGLSVAEQIVLYQELAAHDA
PRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGEIWVQGFSEPEAGSDLASLRTTAHRTGDTFVVNGQKLWASGGMH
ADWCLLLARTDPDAPKRKGISYFLLDMTTPGVDVRPIRNAVGDSHFCEIFLNDVEIPAANLVGAENAGWQVAQETLGAER
GMTMLELAERLANAGFRRLVRTSPVDDPVVADRLAQFECEITALRGLCRKVVEGHDSGAIGPADASIVKLYYSELLQRLT
DFGAEIGGPAGHTEIAKPMSSGWESGSWVLDFIGSWEWTIPGGSSEIQRTIIGERGLGLPREPSAV
>Mature_385_residues
SIDDFRATVRAWCAEHVPSDWREKQTGVGDEEFVRFQKAWFAELHSAGYAVPHWPAEWGGGLSVAEQIVLYQELAAHDAP
RLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGEIWVQGFSEPEAGSDLASLRTTAHRTGDTFVVNGQKLWASGGMHA
DWCLLLARTDPDAPKRKGISYFLLDMTTPGVDVRPIRNAVGDSHFCEIFLNDVEIPAANLVGAENAGWQVAQETLGAERG
MTMLELAERLANAGFRRLVRTSPVDDPVVADRLAQFECEITALRGLCRKVVEGHDSGAIGPADASIVKLYYSELLQRLTD
FGAEIGGPAGHTEIAKPMSSGWESGSWVLDFIGSWEWTIPGGSSEIQRTIIGERGLGLPREPSAV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=387, Percent_Identity=25.5813953488372, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=27.4611398963731, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=27.4611398963731, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=26.4094955489614, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4501859, Length=323, Percent_Identity=28.4829721362229, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4501857, Length=285, Percent_Identity=25.6140350877193, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI7656849, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI21361497, Length=249, Percent_Identity=27.710843373494, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4557235, Length=300, Percent_Identity=27, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38505218, Length=257, Percent_Identity=29.1828793774319, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI76496475, Length=300, Percent_Identity=27, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557233, Length=358, Percent_Identity=26.2569832402235, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI211971008, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI48976061, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=348, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786223, Length=274, Percent_Identity=24.0875912408759, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=350, Percent_Identity=27.4285714285714, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17570075, Length=393, Percent_Identity=26.972010178117, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17534899, Length=345, Percent_Identity=27.8260869565217, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17538396, Length=332, Percent_Identity=27.1084337349398, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=290, Percent_Identity=29.3103448275862, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=275, Percent_Identity=29.0909090909091, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=204, Percent_Identity=32.3529411764706, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=271, Percent_Identity=27.3062730627306, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=305, Percent_Identity=27.8688524590164, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=209, Percent_Identity=30.622009569378, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=209, Percent_Identity=30.622009569378, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=204, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=304, Percent_Identity=25.9868421052632, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=262, Percent_Identity=25.9541984732824, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666513, Length=271, Percent_Identity=29.1512915129151, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355753, Length=334, Percent_Identity=27.2455089820359, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=354, Percent_Identity=26.8361581920904, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363737, Length=299, Percent_Identity=27.0903010033445, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356377, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646207, Length=188, Percent_Identity=30.3191489361702, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42101; Mature: 41970

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDDFRATVRAWCAEHVPSDWREKQTGVGDEEFVRFQKAWFAELHSAGYAVPHWPAEWG
CCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHC
GGLSVAEQIVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGEIWV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCEECCCEEE
QGFSEPEAGSDLASLRTTAHRTGDTFVVNGQKLWASGGMHADWCLLLARTDPDAPKRKGI
ECCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCEEEEEECCCCCCHHHCCC
SYFLLDMTTPGVDVRPIRNAVGDSHFCEIFLNDVEIPAANLVGAENAGWQVAQETLGAER
EEEEEEECCCCCCHHHHHHHHCCCCEEHEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHH
GMTMLELAERLANAGFRRLVRTSPVDDPVVADRLAQFECEITALRGLCRKVVEGHDSGAI
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPADASIVKLYYSELLQRLTDFGAEIGGPAGHTEIAKPMSSGWESGSWVLDFIGSWEWTI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEECCCEEEEC
PGGSSEIQRTIIGERGLGLPREPSAV
CCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIDDFRATVRAWCAEHVPSDWREKQTGVGDEEFVRFQKAWFAELHSAGYAVPHWPAEWG
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHC
GGLSVAEQIVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGEIWV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCEECCCEEE
QGFSEPEAGSDLASLRTTAHRTGDTFVVNGQKLWASGGMHADWCLLLARTDPDAPKRKGI
ECCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCEEEEEECCCCCCHHHCCC
SYFLLDMTTPGVDVRPIRNAVGDSHFCEIFLNDVEIPAANLVGAENAGWQVAQETLGAER
EEEEEEECCCCCCHHHHHHHHCCCCEEHEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHH
GMTMLELAERLANAGFRRLVRTSPVDDPVVADRLAQFECEITALRGLCRKVVEGHDSGAI
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPADASIVKLYYSELLQRLTDFGAEIGGPAGHTEIAKPMSSGWESGSWVLDFIGSWEWTI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEECCCEEEEC
PGGSSEIQRTIIGERGLGLPREPSAV
CCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]