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The map label for this gene is mmgC [H]

Identifier: 108801360

GI number: 108801360

Start: 4675839

End: 4676798

Strand: Reverse

Name: mmgC [H]

Synonym: Mmcs_4397

Alternate gene names: 108801360

Gene position: 4676798-4675839 (Counterclockwise)

Preceding gene: 108801361

Following gene: 108801359

Centisome position: 81.97

GC content: 68.96

Gene sequence:

>960_bases
ATGGGCTTCGAGGAGTTCCATGACGAGTTGCGGTCCGTCGCGGCCGACGTGCTGGACAAAGGGCGCGAGGTGGACTGGCC
CGTACTCGTCGACGCAGGGTGGGTGGGCCTCGAGGTGCCCGAGCACCTCGGTGGCGCCGGCGCCACCTTCGCCGAGACCG
CGGTGATCTGCCGGGAAATGGGCCGCGCCGCCACCGCCGGAAGCTTCCTCGGCAGCGCCGTCCTCGCGGTCGGCACGCTG
AATGCGTTGCAGCCGAGCGACACCCGGGACCAGCTGCTGGCCGGCATCGCATCCGGCGACGTCCGGGTCGCCGTCGCACT
CGAATCGCTGGACTTCGTCCCCGACGCCGACGGCGCCGACCGGCTTCTGGTGGTGACCAACGGCGCGGTCGCGGTGGCCG
AACTCGATGTGACGCCAGTGCCCGTCGTCGACGAGACACGCCGACTGGGGAAGGTCTCGTCGCGCACGTTGGAGCCACCG
ACGATGCTGCGCTTCGAGGGGGACGCCGACAACGCGGTGCGCCGGCTGCACGACCGGGCCGCCGTCGCCGTCGCCTGCGA
CAGTCTCGGACTCGCCGAGGCGATGCTGTCCGCAACCGTCGAATACGCCAAGGTGCGTTCACAATTCGGCAGGCCCATCG
GATCTTTCCAGGCGGTCAAACACGCCTGCGCCGACATGCTCGTGCAGATCGAGGTGTCCCGCCAACTGGTCGAGGCGGCC
GTCGACGCCGTCGTCGCCGGCGACGCGACCGCGGCCGCGGCCATGGCGAAGTCCCACGTCTGCAGTGCGGCGGTCGACGT
CGCGGGCAAGGCCATGCAATTGCACGGAGGTATCGGATACACCTGGGAGAGCGGCGTCCACGTCTATCTCAAACGTGCCG
CGCTCAACCGCTCGCTGTTCGGATCCCCTGCGGCACACCGCAGACAACTCGCTCAACGCTATCGGAATCAAGGAGAGTAA

Upstream 100 bases:

>100_bases
GCTCCTGGGAGTGGACGATCCCCGGCGGTTCGAGCGAGATCCAGCGCACCATCATCGGTGAGCGCGGCCTCGGCCTGCCC
CGAGAACCGAGCGCAGTCTG

Downstream 100 bases:

>100_bases
TTCCATGGGTGTCCCCGTCTACAAACGCATTCTCGACCTGTTCGAGGCCGAGGGTGTGAACACGTTGTTCGGCATCCCGG
ATCCGAACTTCGTGCACATG

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MGFEEFHDELRSVAADVLDKGREVDWPVLVDAGWVGLEVPEHLGGAGATFAETAVICREMGRAATAGSFLGSAVLAVGTL
NALQPSDTRDQLLAGIASGDVRVAVALESLDFVPDADGADRLLVVTNGAVAVAELDVTPVPVVDETRRLGKVSSRTLEPP
TMLRFEGDADNAVRRLHDRAAVAVACDSLGLAEAMLSATVEYAKVRSQFGRPIGSFQAVKHACADMLVQIEVSRQLVEAA
VDAVVAGDATAAAAMAKSHVCSAAVDVAGKAMQLHGGIGYTWESGVHVYLKRAALNRSLFGSPAAHRRQLAQRYRNQGE

Sequences:

>Translated_319_residues
MGFEEFHDELRSVAADVLDKGREVDWPVLVDAGWVGLEVPEHLGGAGATFAETAVICREMGRAATAGSFLGSAVLAVGTL
NALQPSDTRDQLLAGIASGDVRVAVALESLDFVPDADGADRLLVVTNGAVAVAELDVTPVPVVDETRRLGKVSSRTLEPP
TMLRFEGDADNAVRRLHDRAAVAVACDSLGLAEAMLSATVEYAKVRSQFGRPIGSFQAVKHACADMLVQIEVSRQLVEAA
VDAVVAGDATAAAAMAKSHVCSAAVDVAGKAMQLHGGIGYTWESGVHVYLKRAALNRSLFGSPAAHRRQLAQRYRNQGE
>Mature_318_residues
GFEEFHDELRSVAADVLDKGREVDWPVLVDAGWVGLEVPEHLGGAGATFAETAVICREMGRAATAGSFLGSAVLAVGTLN
ALQPSDTRDQLLAGIASGDVRVAVALESLDFVPDADGADRLLVVTNGAVAVAELDVTPVPVVDETRRLGKVSSRTLEPPT
MLRFEGDADNAVRRLHDRAAVAVACDSLGLAEAMLSATVEYAKVRSQFGRPIGSFQAVKHACADMLVQIEVSRQLVEAAV
DAVVAGDATAAAAMAKSHVCSAAVDVAGKAMQLHGGIGYTWESGVHVYLKRAALNRSLFGSPAAHRRQLAQRYRNQGE

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786223, Length=124, Percent_Identity=33.0645161290323, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 33523; Mature: 33392

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFEEFHDELRSVAADVLDKGREVDWPVLVDAGWVGLEVPEHLGGAGATFAETAVICREM
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHH
GRAATAGSFLGSAVLAVGTLNALQPSDTRDQLLAGIASGDVRVAVALESLDFVPDADGAD
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCC
RLLVVTNGAVAVAELDVTPVPVVDETRRLGKVSSRTLEPPTMLRFEGDADNAVRRLHDRA
EEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
AVAVACDSLGLAEAMLSATVEYAKVRSQFGRPIGSFQAVKHACADMLVQIEVSRQLVEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAVVAGDATAAAAMAKSHVCSAAVDVAGKAMQLHGGIGYTWESGVHVYLKRAALNRSLF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEECCCHHHHHHHHHHHHHHC
GSPAAHRRQLAQRYRNQGE
CCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GFEEFHDELRSVAADVLDKGREVDWPVLVDAGWVGLEVPEHLGGAGATFAETAVICREM
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHH
GRAATAGSFLGSAVLAVGTLNALQPSDTRDQLLAGIASGDVRVAVALESLDFVPDADGAD
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCC
RLLVVTNGAVAVAELDVTPVPVVDETRRLGKVSSRTLEPPTMLRFEGDADNAVRRLHDRA
EEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
AVAVACDSLGLAEAMLSATVEYAKVRSQFGRPIGSFQAVKHACADMLVQIEVSRQLVEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAVVAGDATAAAAMAKSHVCSAAVDVAGKAMQLHGGIGYTWESGVHVYLKRAALNRSLF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEECCCHHHHHHHHHHHHHHC
GSPAAHRRQLAQRYRNQGE
CCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]