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The map label for this gene is sucC

Identifier: 108801291

GI number: 108801291

Start: 4600835

End: 4601998

Strand: Reverse

Name: sucC

Synonym: Mmcs_4327

Alternate gene names: 108801291

Gene position: 4601998-4600835 (Counterclockwise)

Preceding gene: 108801294

Following gene: 108801290

Centisome position: 80.66

GC content: 66.75

Gene sequence:

>1164_bases
ATGGACCTTTTCGAGTACCAGGCGAAGGAGCTGTTCGCCAAGCACAACGTCCCGACCACGCCTGGCCGGGTGACCGACAC
CGCCGAAGACGCCAAGGCGATCGCCGAGGAGATCGGCAAGCCCGTGATGGTCAAGGCCCAGGTCAAGGTCGGCGGCCGCG
GTAAGGCCGGTGGCGTGAAGTACGCCGCCACCGCAGACGACGCCTTCACCCACGCGCAGAACATCCTCGGCCTCGACATC
AAGGGCCATGTCGTGAAGAAGCTCCTGGTCGCCGAGGCCAGCGACATCGCGGAGGAGTACTACATCTCCTTCCTCCTCGA
CCGCGCCAACCGCACCTACCTGGCCATGTGCTCGGTCGAGGGCGGCGTGGAGATCGAAGAGGTCGCCGCCACCAAGCCCG
ACCGCCTGGCCCGCATCCCCGTCGACGCCACCAAGGGTGTCGACGAGGCCTTCGCGCGCGAGATCGCCGAGAAGGGCCAC
CTGCCCGCCGAGGTGCTCGACGCCGCCGCGGTGACCATCGCCAAGCTGTGGGAGGTGTTCGTCGGCGAGGACGCCACGCT
GGTGGAGGTCAACCCGCTGGTGCGCACGCCCGACGATCAGATCCTGGCGCTCGACGGCAAGGTCACCCTCGACGCGAACG
CCGACTTCCGTCATCCGGAGCACGCCGAGTTCGAGGACCGCGATGCGACCGATCCGCTGGAGCTCAAGGCCAAGGAGAAC
GACCTCAACTACGTCAAACTCGACGGGCAGGTCGGCATCATCGGCAACGGCGCGGGCCTGGTCATGTCGACGCTCGATGT
GGTCGCCTACGCGGGTGAGAAGCACAACGGCGTCAAGCCGGCCAACTTCCTCGACATCGGCGGCGGCGCCTCGGCCGAGG
TGATGGCCAACGGTCTGGACGTCATCCTGAACGACAGCCAGGTCAAGAGTGTGTTCGTCAACGTCTTCGGCGGCATCACG
GCGTGCGATGCCGTCGCCAACGGCATCGTCAAGGCGCTCGAGATCCTCGGCGAGGAAGCCAACAAGCCGCTCGTAGTGCG
CCTCGACGGCAACCGCGTCGAGGAGGGTCGCAAGATCCTCGCCGACGCCAACCACCCGCTGGTGGTGCTGGCGCAGACCA
TGGACGAGGGCGCCGACAAGGCCGCCGAGTTGGCGAACAAGTAA

Upstream 100 bases:

>100_bases
GTGACGACCGGCTGAGCCGGTGTGGATAAGGTTCCCACGAGCCCCCTGGGTGCAAACCTTCGAAATATCGTGACCGTCAA
CGCAGACAGACAGTGAGTCC

Downstream 100 bases:

>100_bases
GGGACCTGCAATGTCGATCTTTCTGAACAAGGACTCCAAGGTCATCGTCCAGGGCATCACCGGCGGTGAGGGCACCAAGC
ACACCGCGCTGATGCTCAAG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDLFEYQAKELFAKHNVPTTPGRVTDTAEDAKAIAEEIGKPVMVKAQVKVGGRGKAGGVKYAATADDAFTHAQNILGLDI
KGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEEVAATKPDRLARIPVDATKGVDEAFAREIAEKGH
LPAEVLDAAAVTIAKLWEVFVGEDATLVEVNPLVRTPDDQILALDGKVTLDANADFRHPEHAEFEDRDATDPLELKAKEN
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHNGVKPANFLDIGGGASAEVMANGLDVILNDSQVKSVFVNVFGGIT
ACDAVANGIVKALEILGEEANKPLVVRLDGNRVEEGRKILADANHPLVVLAQTMDEGADKAAELANK

Sequences:

>Translated_387_residues
MDLFEYQAKELFAKHNVPTTPGRVTDTAEDAKAIAEEIGKPVMVKAQVKVGGRGKAGGVKYAATADDAFTHAQNILGLDI
KGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEEVAATKPDRLARIPVDATKGVDEAFAREIAEKGH
LPAEVLDAAAVTIAKLWEVFVGEDATLVEVNPLVRTPDDQILALDGKVTLDANADFRHPEHAEFEDRDATDPLELKAKEN
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHNGVKPANFLDIGGGASAEVMANGLDVILNDSQVKSVFVNVFGGIT
ACDAVANGIVKALEILGEEANKPLVVRLDGNRVEEGRKILADANHPLVVLAQTMDEGADKAAELANK
>Mature_387_residues
MDLFEYQAKELFAKHNVPTTPGRVTDTAEDAKAIAEEIGKPVMVKAQVKVGGRGKAGGVKYAATADDAFTHAQNILGLDI
KGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEEVAATKPDRLARIPVDATKGVDEAFAREIAEKGH
LPAEVLDAAAVTIAKLWEVFVGEDATLVEVNPLVRTPDDQILALDGKVTLDANADFRHPEHAEFEDRDATDPLELKAKEN
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHNGVKPANFLDIGGGASAEVMANGLDVILNDSQVKSVFVNVFGGIT
ACDAVANGIVKALEILGEEANKPLVVRLDGNRVEEGRKILADANHPLVVLAQTMDEGADKAAELANK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=401, Percent_Identity=34.9127182044888, Blast_Score=243, Evalue=1e-64,
Organism=Homo sapiens, GI157779135, Length=382, Percent_Identity=36.9109947643979, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI294862256, Length=370, Percent_Identity=36.7567567567568, Blast_Score=228, Evalue=7e-60,
Organism=Escherichia coli, GI1786948, Length=371, Percent_Identity=42.5876010781671, Blast_Score=268, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17567829, Length=400, Percent_Identity=35.75, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=33.9195979899498, Blast_Score=231, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6321683, Length=404, Percent_Identity=35.1485148514851, Blast_Score=235, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21356231, Length=402, Percent_Identity=34.3283582089552, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI161078106, Length=403, Percent_Identity=35.9801488833747, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24645208, Length=403, Percent_Identity=35.9801488833747, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI281361397, Length=404, Percent_Identity=35.8910891089109, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281361395, Length=404, Percent_Identity=35.8910891089109, Blast_Score=217, Evalue=1e-56,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_MYCSJ (A3Q5P5)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001072963.1
- ProteinModelPortal:   A3Q5P5
- SMR:   A3Q5P5
- STRING:   A3Q5P5
- EnsemblBacteria:   EBMYCT00000051422
- GeneID:   4880406
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_4707
- eggNOG:   COG0045
- GeneTree:   EBGT00050000017263
- HOGENOM:   HBG315432
- OMA:   KKELYVS
- ProtClustDB:   PRK00696
- BioCyc:   MSP164757:MJLS_4707-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41170; Mature: 41170

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFEYQAKELFAKHNVPTTPGRVTDTAEDAKAIAEEIGKPVMVKAQVKVGGRGKAGGVK
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATADDAFTHAQNILGLDIKGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVE
EEECCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGVEIEEVAATKPDRLARIPVDATKGVDEAFAREIAEKGHLPAEVLDAAAVTIAKLWEVF
CCCCHHHHHCCCCCCEEECCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VGEDATLVEVNPLVRTPDDQILALDGKVTLDANADFRHPEHAEFEDRDATDPLELKAKEN
HCCCCEEEEECCCEECCCCCEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECC
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHNGVKPANFLDIGGGASAEVMANGLD
CCCEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHCCCE
VILNDSQVKSVFVNVFGGITACDAVANGIVKALEILGEEANKPLVVRLDGNRVEEGRKIL
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCHHHE
ADANHPLVVLAQTMDEGADKAAELANK
ECCCCCEEEEEEHHCCCHHHHHHHHCC
>Mature Secondary Structure
MDLFEYQAKELFAKHNVPTTPGRVTDTAEDAKAIAEEIGKPVMVKAQVKVGGRGKAGGVK
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATADDAFTHAQNILGLDIKGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVE
EEECCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGVEIEEVAATKPDRLARIPVDATKGVDEAFAREIAEKGHLPAEVLDAAAVTIAKLWEVF
CCCCHHHHHCCCCCCEEECCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VGEDATLVEVNPLVRTPDDQILALDGKVTLDANADFRHPEHAEFEDRDATDPLELKAKEN
HCCCCEEEEECCCEECCCCCEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECC
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHNGVKPANFLDIGGGASAEVMANGLD
CCCEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHCCCE
VILNDSQVKSVFVNVFGGITACDAVANGIVKALEILGEEANKPLVVRLDGNRVEEGRKIL
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCHHHE
ADANHPLVVLAQTMDEGADKAAELANK
ECCCCCEEEEEEHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA