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The map label for this gene is desA2 [H]

Identifier: 108801094

GI number: 108801094

Start: 4396751

End: 4397578

Strand: Reverse

Name: desA2 [H]

Synonym: Mmcs_4130

Alternate gene names: 108801094

Gene position: 4397578-4396751 (Counterclockwise)

Preceding gene: 108801095

Following gene: 108801093

Centisome position: 77.08

GC content: 66.18

Gene sequence:

>828_bases
ATGGCACAGAAACCTGTCCCTAACGCGCTGACCCTCGAGCTGGAGCCGGTCGTCAAGGACGAACTGCGTCGCCACCTCGA
CTCCGAGGACCTCTGGTTCGCGCACGACTACGTGCCGTTCGACCAGGGCGAGAACTTCGCGTTCCTCGGCGGTCGGGACT
GGGACCCGTCGCAGGTGACGCTGCCCAAACACGTCACCGACGCGCTCGAGATCCTGTTGATCACCAAGGACAACCTCGCC
GGCTACCACCGCGAACTCGTCGAGCACTTCATCCTCGAGGAGAAGTGGGGCCGTTGGATCGGCCGCTGGACCGCCGAGGA
ACATCTGCATGCCGTCGCGCTGCGCAACTACCTGGTCGTCACCCGCGAGGTGGACCCGGTCGCCAACGAGGACGTGCGCG
TCGAGCACGTCATGAAGGGCTACCGCGCCGACCGCTTCAGCCAGATCGAGACGCTGGTGTTCATGGCGTTCTTCGAGCGG
TCCCACGCCGTGTTCACCCGCAACCTCGAGGCGCAGATCGCCGAGCCGGTCCTCAAGGGACTGGTCGGCCGGATCGCCGC
CGACGAGGAGCGCCACGAGGTGTTCTTCGCCAACCTGGTCGCGCACTGCCTGCAGACCCACCGCGACGAGACCGTGGCGG
CGATCGCCGCGCGGGCCCGCGAACTCGGGGTGGTCGGCGGTGACATCGACGCCTACCTGGACAAGGTGGCCGCGATGGCC
GAACACGGCATCTTCGACGAGGCCCAGTTGCGCAAGGTCATCTCCGACCGGATCAGCGCCTGGGAACTGTCCGGTGAACC
GGTGTTGCAGGAGTTCACGAACGCTTAA

Upstream 100 bases:

>100_bases
GAGATGCTCGACGCCAACCCGCTGTATCCGGGTCTCACGCTCTGAGGCGACGCGCCGCGGGAATTTTACGATTCCCACAG
GATTGGGTTACTGTAACCGC

Downstream 100 bases:

>100_bases
CCTGGCGCGCGCCACACACCGGCGCGCCTGCGCGGCGCAGTCCCTGCGACGGGAGTAGCGTCGGCTCCGATGGCTAGCGA
ATTGCTCTGCTGTCCGGGCG

Product: fatty acid desaturase, type 2

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA2 [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MAQKPVPNALTLELEPVVKDELRRHLDSEDLWFAHDYVPFDQGENFAFLGGRDWDPSQVTLPKHVTDALEILLITKDNLA
GYHRELVEHFILEEKWGRWIGRWTAEEHLHAVALRNYLVVTREVDPVANEDVRVEHVMKGYRADRFSQIETLVFMAFFER
SHAVFTRNLEAQIAEPVLKGLVGRIAADEERHEVFFANLVAHCLQTHRDETVAAIAARARELGVVGGDIDAYLDKVAAMA
EHGIFDEAQLRKVISDRISAWELSGEPVLQEFTNA

Sequences:

>Translated_275_residues
MAQKPVPNALTLELEPVVKDELRRHLDSEDLWFAHDYVPFDQGENFAFLGGRDWDPSQVTLPKHVTDALEILLITKDNLA
GYHRELVEHFILEEKWGRWIGRWTAEEHLHAVALRNYLVVTREVDPVANEDVRVEHVMKGYRADRFSQIETLVFMAFFER
SHAVFTRNLEAQIAEPVLKGLVGRIAADEERHEVFFANLVAHCLQTHRDETVAAIAARARELGVVGGDIDAYLDKVAAMA
EHGIFDEAQLRKVISDRISAWELSGEPVLQEFTNA
>Mature_274_residues
AQKPVPNALTLELEPVVKDELRRHLDSEDLWFAHDYVPFDQGENFAFLGGRDWDPSQVTLPKHVTDALEILLITKDNLAG
YHRELVEHFILEEKWGRWIGRWTAEEHLHAVALRNYLVVTREVDPVANEDVRVEHVMKGYRADRFSQIETLVFMAFFERS
HAVFTRNLEAQIAEPVLKGLVGRIAADEERHEVFFANLVAHCLQTHRDETVAAIAARARELGVVGGDIDAYLDKVAAMAE
HGIFDEAQLRKVISDRISAWELSGEPVLQEFTNA

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 31370; Mature: 31239

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKPVPNALTLELEPVVKDELRRHLDSEDLWFAHDYVPFDQGENFAFLGGRDWDPSQVT
CCCCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCEE
LPKHVTDALEILLITKDNLAGYHRELVEHFILEEKWGRWIGRWTAEEHLHAVALRNYLVV
CHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TREVDPVANEDVRVEHVMKGYRADRFSQIETLVFMAFFERSHAVFTRNLEAQIAEPVLKG
EECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHH
LVGRIAADEERHEVFFANLVAHCLQTHRDETVAAIAARARELGVVGGDIDAYLDKVAAMA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EHGIFDEAQLRKVISDRISAWELSGEPVLQEFTNA
HCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHCCC
>Mature Secondary Structure 
AQKPVPNALTLELEPVVKDELRRHLDSEDLWFAHDYVPFDQGENFAFLGGRDWDPSQVT
CCCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCEE
LPKHVTDALEILLITKDNLAGYHRELVEHFILEEKWGRWIGRWTAEEHLHAVALRNYLVV
CHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TREVDPVANEDVRVEHVMKGYRADRFSQIETLVFMAFFERSHAVFTRNLEAQIAEPVLKG
EECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHH
LVGRIAADEERHEVFFANLVAHCLQTHRDETVAAIAARARELGVVGGDIDAYLDKVAAMA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EHGIFDEAQLRKVISDRISAWELSGEPVLQEFTNA
HCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]