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The map label for this gene is dapL [H]

Identifier: 108800993

GI number: 108800993

Start: 4294685

End: 4295677

Strand: Reverse

Name: dapL [H]

Synonym: Mmcs_4029

Alternate gene names: 108800993

Gene position: 4295677-4294685 (Counterclockwise)

Preceding gene: 108800994

Following gene: 108800992

Centisome position: 75.29

GC content: 72.81

Gene sequence:

>993_bases
GTGGACGAGGTGGCGCCCGTCATCCGTGAGGCGCTCGCGGCGGCCAGTGGCGCGCCCGGGTATCCGACGACCGCGGGAAC
ACCCGAGCTACGGGCGTCGGCGAAGGCCGCGCTCGAACGCCGCTGCGGCATCACCGGCCTGGCGGACGACGCCGTGCTGC
CCGTCATCGGCAGCAAGGAGCTCATCGCGTGGCTGCCCACGCTGCTCGGGGCGGGATCGGACGATCTGGTGGTGGTGCCC
GAACTCGCGTACCCCACCTACGACGTCGGCGCCCGGCTGGCCGGAGCCCAGGTGATCCGGGCCGATTCGCTCACCCAGTT
GGGCCCGCAGCGGCCGGCGCTGATCTTCCTCAACTCGCCGAGCAACCCGACCGGACGGGTACTGGGCGTCGACCACCTCC
GCAAGGTCGTCGGCTGGGCCCGCGACCGCGGGGTGCTCGTCGCCTCCGACGAGTGCTACCTCGGCCTCGCCTGGGACGCC
GAACCGGTCTCCGTGCTGCACCCCTCGGTCTGCGACGGCGACCACACCGGCCTGCTGGCCGTGCATTCGTTGTCCAAGAC
GTCGTCGCTGGCCGGCTACCGCGCCGGCTTCGTCGCAGGCGACCCGGCGGTCATCGCCGAACTGCTCGCGGTGCGTAAGC
ACGCCGGGATGATGGTGCCGACCCCGGTGCAGGCGGCGATGGTGGCCGCCCTCGACGACGACGCCCACGAACGCGAGCAA
CGCGAGCGTTATGCGCGCCGCCGCGAGGTGCTGTTGCCCGCGCTGAAGGCCGCCGGTTACACCGTCGACCATTCCGAGGC
CGGGCTGTACCTGTGGGCCACCCGCGGTGAACCGTGCCGGCAGACGGTCGACCGGCTGGCGCGGCTCGGGATCCTCGCCG
CGCCGGGGGAGTTCTACGGACCACGCGGCGCACAGCACGTCCGACTGGCGCTGACCGCCACCGACGAGCGGATCGCCGCC
GCCGCCGAACGGCTTTCGGCGAATCAGGGTTAG

Upstream 100 bases:

>100_bases
CGCGAAGCTGCCGGAGTTCCCCTGGGACACGCTGGCGGCGGCCGGCGCGCAGGCTCGCGCGCACCCGGACGGCATCGTCG
ACCTGTCGGTCGGCACCCCT

Downstream 100 bases:

>100_bases
CCCGCCGGCACCCGTAATACCGTCGATGCCGTGGACCGGCTTCCGTTCAGCACCGCCGACAAAGCCGAGCGTTACCGCAC
CGAGCGCTTCGCCGGGGCCG

Product: N-succinyldiaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDEVAPVIREALAAASGAPGYPTTAGTPELRASAKAALERRCGITGLADDAVLPVIGSKELIAWLPTLLGAGSDDLVVVP
ELAYPTYDVGARLAGAQVIRADSLTQLGPQRPALIFLNSPSNPTGRVLGVDHLRKVVGWARDRGVLVASDECYLGLAWDA
EPVSVLHPSVCDGDHTGLLAVHSLSKTSSLAGYRAGFVAGDPAVIAELLAVRKHAGMMVPTPVQAAMVAALDDDAHEREQ
RERYARRREVLLPALKAAGYTVDHSEAGLYLWATRGEPCRQTVDRLARLGILAAPGEFYGPRGAQHVRLALTATDERIAA
AAERLSANQG

Sequences:

>Translated_330_residues
MDEVAPVIREALAAASGAPGYPTTAGTPELRASAKAALERRCGITGLADDAVLPVIGSKELIAWLPTLLGAGSDDLVVVP
ELAYPTYDVGARLAGAQVIRADSLTQLGPQRPALIFLNSPSNPTGRVLGVDHLRKVVGWARDRGVLVASDECYLGLAWDA
EPVSVLHPSVCDGDHTGLLAVHSLSKTSSLAGYRAGFVAGDPAVIAELLAVRKHAGMMVPTPVQAAMVAALDDDAHEREQ
RERYARRREVLLPALKAAGYTVDHSEAGLYLWATRGEPCRQTVDRLARLGILAAPGEFYGPRGAQHVRLALTATDERIAA
AAERLSANQG
>Mature_330_residues
MDEVAPVIREALAAASGAPGYPTTAGTPELRASAKAALERRCGITGLADDAVLPVIGSKELIAWLPTLLGAGSDDLVVVP
ELAYPTYDVGARLAGAQVIRADSLTQLGPQRPALIFLNSPSNPTGRVLGVDHLRKVVGWARDRGVLVASDECYLGLAWDA
EPVSVLHPSVCDGDHTGLLAVHSLSKTSSLAGYRAGFVAGDPAVIAELLAVRKHAGMMVPTPVQAAMVAALDDDAHEREQ
RERYARRREVLLPALKAAGYTVDHSEAGLYLWATRGEPCRQTVDRLARLGILAAPGEFYGPRGAQHVRLALTATDERIAA
AAERLSANQG

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=346, Percent_Identity=30.635838150289, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786816, Length=342, Percent_Identity=24.8538011695906, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=290, Percent_Identity=21.0344827586207, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 34778; Mature: 34778

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEVAPVIREALAAASGAPGYPTTAGTPELRASAKAALERRCGITGLADDAVLPVIGSKE
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
LIAWLPTLLGAGSDDLVVVPELAYPTYDVGARLAGAQVIRADSLTQLGPQRPALIFLNSP
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCHHEEECCCHHHCCCCCCEEEEEECC
SNPTGRVLGVDHLRKVVGWARDRGVLVASDECYLGLAWDAEPVSVLHPSVCDGDHTGLLA
CCCCCCEECHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHCCCCCCCCCCCCEEE
VHSLSKTSSLAGYRAGFVAGDPAVIAELLAVRKHAGMMVPTPVQAAMVAALDDDAHEREQ
EECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHH
RERYARRREVLLPALKAAGYTVDHSEAGLYLWATRGEPCRQTVDRLARLGILAAPGEFYG
HHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCHHHHHHHHHHHCCEEECCCCCCC
PRGAQHVRLALTATDERIAAAAERLSANQG
CCCCCEEEEEEEECHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDEVAPVIREALAAASGAPGYPTTAGTPELRASAKAALERRCGITGLADDAVLPVIGSKE
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
LIAWLPTLLGAGSDDLVVVPELAYPTYDVGARLAGAQVIRADSLTQLGPQRPALIFLNSP
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCHHEEECCCHHHCCCCCCEEEEEECC
SNPTGRVLGVDHLRKVVGWARDRGVLVASDECYLGLAWDAEPVSVLHPSVCDGDHTGLLA
CCCCCCEECHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHCCCCCCCCCCCCEEE
VHSLSKTSSLAGYRAGFVAGDPAVIAELLAVRKHAGMMVPTPVQAAMVAALDDDAHEREQ
EECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHH
RERYARRREVLLPALKAAGYTVDHSEAGLYLWATRGEPCRQTVDRLARLGILAAPGEFYG
HHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCHHHHHHHHHHHCCEEECCCCCCC
PRGAQHVRLALTATDERIAAAAERLSANQG
CCCCCEEEEEEEECHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA