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The map label for this gene is argG [H]

Identifier: 108799932

GI number: 108799932

Start: 3130918

End: 3132120

Strand: Reverse

Name: argG [H]

Synonym: Mmcs_2966

Alternate gene names: 108799932

Gene position: 3132120-3130918 (Counterclockwise)

Preceding gene: 108799933

Following gene: 108799931

Centisome position: 54.9

GC content: 66.92

Gene sequence:

>1203_bases
ATGTCCGAACGCGTCATCCTGGCGTACTCCGGCGGTCTGGACACCTCGGTGGCGATCAGCTGGATCGGCAAGGAGACCGG
GCGCGAGGTGGTGGCGGTCGCCATCGACCTCGGTCAGGGCGGCGAGGACATGGACGTCGTGCGCCAGCGTGCCCTCGACT
GCGGTGCGGTCGAAGCCGTCGTCATCGACGCCCGCGACGAGTTCGCCGAGGACTACTGCCTGCCCGCGATCCAGTCCAAC
GCGCTCTACATGGACCGCTATCCGCTGGTGTCCGCGCTCAGCCGGCCGCTGATCGTCAAACACCTCGTGGACGCCGCCCG
CGAACACAAGGGCGGCATCGTCGCGCACGGCTGCACGGGCAAGGGCAACGACCAGGTCCGCTTCGAGGTCGGGTTCGCCT
CGCTGGCACCGGACCTCGAGGTGCTCGCCCCGGTCCGCGACTATGCGTGGACGCGCGAGAAGGCGATCGCGTTCGCCGAG
GAGAACGCGATCCCGATCAACGTCACCAAGCGCTCACCGTTCTCGATCGACCAGAACGTGTGGGGCCGCGCGGTGGAGAC
CGGATTCCTCGAGCACCTGTGGAACGCGCCCACCAAGGACGTCTACGACTACACCGAGGATCCGACACTCAACTGGAGCA
CCCCCGACGAGGTGATCGTCGGGTTCGACAAGGGTGTGCCGGTGTCCATCGACGGCCGCGACGTGACCGTGCTGCAGGCG
ATCGAGGAACTCAACCGCCGTGCGGGCGCGCAGGGTGTGGGCCGCCTCGACGTCGTCGAGGACCGGTTGGTCGGCATCAA
GAGCCGCGAGATCTACGAGGCCCCCGGTGCGATGGTGCTCATCACAGCGCACACCGAACTCGAACACGTCACGCTGGAAC
GCGAACTCGGCCGGTTCAAGCGCACCACCGACCAGAAGTGGGGTGAGCTGGTCTACGACGGGCTGTGGTTCTCCCCGCTG
AAGACCGCGCTCGAGTCGTTCGTCGCCAAGACGCAGGAACACGTCAGCGGTGAGATCCGGCTGGTGCTGCACGGCGGCCA
CATCGCCGTGAATGGACGCCGGAGCCAGGAATCTCTGTACGACTTCAACCTGGCCACCTACGACGAGGGCGACACCTTCG
ACCAGTCCTCGGCCAAGGGCTTCGTGCACGTGCACGGCCTGAGCTCGAGCATCTCCGCGCGCCGCGACCTCGGCATCAAG
TGA

Upstream 100 bases:

>100_bases
ATCGCCGGCGACGACACCATCATGGTGGTGGCCCGCGAGCCCATGACGGGCGTCGAGCTGGCCGCCACCCTTGAGAACCT
GAAGTAAGAGGAGATTGGTC

Downstream 100 bases:

>100_bases
GCGATCGGTGAGCACCAACGAAGGCTCACTGTGGGGCGGCCGGTTCGCCGACGGACCCGCCGACGCGCTGGCGGCGCTGA
GCAAGTCGACGCATTTCGAC

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEDMDVVRQRALDCGAVEAVVIDARDEFAEDYCLPAIQSN
ALYMDRYPLVSALSRPLIVKHLVDAAREHKGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAE
ENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYDYTEDPTLNWSTPDEVIVGFDKGVPVSIDGRDVTVLQA
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRTTDQKWGELVYDGLWFSPL
KTALESFVAKTQEHVSGEIRLVLHGGHIAVNGRRSQESLYDFNLATYDEGDTFDQSSAKGFVHVHGLSSSISARRDLGIK

Sequences:

>Translated_400_residues
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEDMDVVRQRALDCGAVEAVVIDARDEFAEDYCLPAIQSN
ALYMDRYPLVSALSRPLIVKHLVDAAREHKGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAE
ENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYDYTEDPTLNWSTPDEVIVGFDKGVPVSIDGRDVTVLQA
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRTTDQKWGELVYDGLWFSPL
KTALESFVAKTQEHVSGEIRLVLHGGHIAVNGRRSQESLYDFNLATYDEGDTFDQSSAKGFVHVHGLSSSISARRDLGIK
>Mature_399_residues
SERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEDMDVVRQRALDCGAVEAVVIDARDEFAEDYCLPAIQSNA
LYMDRYPLVSALSRPLIVKHLVDAAREHKGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEE
NAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYDYTEDPTLNWSTPDEVIVGFDKGVPVSIDGRDVTVLQAI
EELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRTTDQKWGELVYDGLWFSPLK
TALESFVAKTQEHVSGEIRLVLHGGHIAVNGRRSQESLYDFNLATYDEGDTFDQSSAKGFVHVHGLSSSISARRDLGIK

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=408, Percent_Identity=39.4607843137255, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI16950633, Length=408, Percent_Identity=39.4607843137255, Blast_Score=277, Evalue=1e-74,
Organism=Escherichia coli, GI1789563, Length=395, Percent_Identity=29.3670886075949, Blast_Score=121, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324514, Length=400, Percent_Identity=35.25, Blast_Score=255, Evalue=8e-69,
Organism=Drosophila melanogaster, GI21358151, Length=400, Percent_Identity=36.5, Blast_Score=261, Evalue=6e-70,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44050; Mature: 43919

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEDMDVVRQRALDCGAVEAV
CCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
VIDARDEFAEDYCLPAIQSNALYMDRYPLVSALSRPLIVKHLVDAAREHKGGIVAHGCTG
EEECCHHHHHHHCCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCC
KGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNV
CCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHH
WGRAVETGFLEHLWNAPTKDVYDYTEDPTLNWSTPDEVIVGFDKGVPVSIDGRDVTVLQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHH
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFK
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RTTDQKWGELVYDGLWFSPLKTALESFVAKTQEHVSGEIRLVLHGGHIAVNGRRSQESLY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCCHHE
DFNLATYDEGDTFDQSSAKGFVHVHGLSSSISARRDLGIK
ECCEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCC
>Mature Secondary Structure 
SERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEDMDVVRQRALDCGAVEAV
CCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
VIDARDEFAEDYCLPAIQSNALYMDRYPLVSALSRPLIVKHLVDAAREHKGGIVAHGCTG
EEECCHHHHHHHCCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCC
KGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNV
CCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHH
WGRAVETGFLEHLWNAPTKDVYDYTEDPTLNWSTPDEVIVGFDKGVPVSIDGRDVTVLQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHH
IEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFK
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RTTDQKWGELVYDGLWFSPLKTALESFVAKTQEHVSGEIRLVLHGGHIAVNGRRSQESLY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCCHHE
DFNLATYDEGDTFDQSSAKGFVHVHGLSSSISARRDLGIK
ECCEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA