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The map label for this gene is pta [H]

Identifier: 108797517

GI number: 108797517

Start: 594117

End: 596231

Strand: Direct

Name: pta [H]

Synonym: Mmcs_0537

Alternate gene names: 108797517

Gene position: 594117-596231 (Clockwise)

Preceding gene: 108797512

Following gene: 108797518

Centisome position: 10.41

GC content: 68.23

Gene sequence:

>2115_bases
ATGTCGCTGATGCGGCAGGCTGTGAGGGTGCCTGACCAGACCGACTCGCGGGTTTCCGCCATCTACGTCGCGTCGCCGGA
GGGCGACACAGGAAAATCCACCATCGCGCTCGGACTGCTCGACCGCCTGACGGCGACCGCGCCCCGGGTCGGGGTGTTCC
GGCCCATCACCCGATCGGGGCCGGCGCGCGACTACATCCTCGAACTGCTGCTCGCACACTCCACCGCGGGTCTGACGTAC
GAGGACAGCGTCGGCGTCACCTACCACCAATTGCACGAGGATCCCGACAGCGCACTCGCCGACATAGTCGACCGCTTCCA
CCGCGTCGCCGACCGATGCGACGTGGTGCTGATTGTCGGCAGCGACTACACCGACGTGGCGAGCCCCAGCGAGCTGTCGA
TGAACGCGCGCATCGCCGCCAACCTCGGCGCGCCGGTCGTCCTCGCCGTCAAGGCCCGCGGGCGCACCCCAGACGACGTG
GTGCAGGTCGTCGAGGTGTGTCTCGACGAGATCGCCGCCCAACACGCCTACACCGCCGCGGTGGTCGCCAACCGGTGCGA
TCCCGACCAGCTCACCGAGGTGCGCGAGGCGCTGAAACGTGACGGCGCCCCGCAGGTCTACGTGCTGCCCGAGGAACCGC
TGCTGGTCGCACCGTCGGTCGCCGAACTGCGCGATGCCGTCGACGGGTCGATGGTCAGCGGTGACGAGTCGCTTCTCGAC
CGCGAGGCGTTGGATGTGCTGGTCGCCGGAATGACCGCCGAGCACGTGCTGGAGCGGCTGACCGAAGGCGTCACGGTCGT
CACGCCGGGCGACCGGTCCGACGTGGTACTCGCCGTCGTGAGCGCCCATGCGGCCGAGGGTTTTCCGTCGCTGTCGAGCA
TCATCCTCAACGGCGGGCTGGAACTGCACCCGTCGATCGCGAAGCTGGTCGCCGGGCTCGGGCTTCGGCTGCCGATCGTC
GCCACCGGGTACGGCACGTTCGAAACCGCCAGCCGGGTGGCAGGCACCAGGGGGCGGGTGACTGCGGCCTCGGTGCGCAA
GATCGACACCGCGCTGACGCTCATGGAGACCCACGTCGACACCGCAGAACTGCTGAGCCGCCTGGCGATCCCGATCCCCA
CTGTCGTCACGCCGCAGATGTTCACCTACCAACTGCTCGACCAGGCCCGGTCGGATCGCAAACGCATCGTGCTGCCCGAG
GGGGACGACGACCGGATCCTCAAAGCGGCCGGGCGACTGCTCCAGCGCGGCGTCGCGGACCTCACGATCCTCGGCGAGGA
GGGCCCGGTACGGGCGCGCGCGGCCGAACTCGGTGTCGACCTCGCGGCGGCAACGGTGCTCGACCCGCGCACCAGTGAGC
TGTGCGACCAGTTCGCCGAGCAATACGCAGAACTGCGCAGGCACAAGGGCGTCACCGTCGAGCAGGCCCGCGAGATCATC
CACGACGTCTCGTACTTCGGCACCATGTTGGTGCACAACGACATGGTCGACGGCATGGTCTCCGGTGCCGCGCACACGAC
GGCGCACACGGTCCGTCCGGCGTTCGAGATCATCAAGACCCTGCCCGATGTGTCGACGGTGTCGAGCATCTTCTTGATGT
GCCTGGCCGACCGCGTGCTCGCCTACGGCGACTGCGCGATCGTTCCCGACCCGACAGCCGAACAGCTGGCCGACATCGCC
ATCTCGTCCGCGCGCACCGCGGCGCAGTTCGGCATCGAGCCGCGGGTGGCGATGCTGTCCTACTCGACAGGGACCTCCGG
TACCGGCGCTGACGTCGAAAAGGTCCGCGAGGCAACGGACCTGGTGCACAAGCGGGAACCCGACCTGCTCGTCGAGGGGC
CGATCCAGTACGACGCCGCAGTGGAACCGTCGGTCGCCAAGACCAAGATGCCGGATTCACCCGTCGCCGGCCGCGCCACC
GTGCTGATCTTCCCCGACCTCAACACCGGCAACAACACGTACAAGGCGGTGCAGCGCAGCGCAGGGGCCATCGCCATCGG
TCCGGTGCTGCAGGGGCTCAACAAACCGGTCAACGACCTGTCACGCGGTGCGTTGGTAGAGGACATCGTCAACACGGTCG
CGATCACCGCGATCCAGGCCCAGGGAGATCGATGA

Upstream 100 bases:

>100_bases
GCTAACGGCGTGTGCGTGCGAAGGTAGCAAATAGTTAGTCAATAACCAAACTATTAACACTCTGCGCGTTCAAACCTGTT
CGAGCGGCCTGCTGGCCGCG

Downstream 100 bases:

>100_bases
CCCGCACAGTGCTCGTGCTCAACTCCGGGTCCTCGTCGCTGAAATTCCAACTGCTCGAACCGGACTCCGGGGCCTCACTG
GCCGACGGGATCGTCGAGCG

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSLMRQAVRVPDQTDSRVSAIYVASPEGDTGKSTIALGLLDRLTATAPRVGVFRPITRSGPARDYILELLLAHSTAGLTY
EDSVGVTYHQLHEDPDSALADIVDRFHRVADRCDVVLIVGSDYTDVASPSELSMNARIAANLGAPVVLAVKARGRTPDDV
VQVVEVCLDEIAAQHAYTAAVVANRCDPDQLTEVREALKRDGAPQVYVLPEEPLLVAPSVAELRDAVDGSMVSGDESLLD
REALDVLVAGMTAEHVLERLTEGVTVVTPGDRSDVVLAVVSAHAAEGFPSLSSIILNGGLELHPSIAKLVAGLGLRLPIV
ATGYGTFETASRVAGTRGRVTAASVRKIDTALTLMETHVDTAELLSRLAIPIPTVVTPQMFTYQLLDQARSDRKRIVLPE
GDDDRILKAAGRLLQRGVADLTILGEEGPVRARAAELGVDLAAATVLDPRTSELCDQFAEQYAELRRHKGVTVEQAREII
HDVSYFGTMLVHNDMVDGMVSGAAHTTAHTVRPAFEIIKTLPDVSTVSSIFLMCLADRVLAYGDCAIVPDPTAEQLADIA
ISSARTAAQFGIEPRVAMLSYSTGTSGTGADVEKVREATDLVHKREPDLLVEGPIQYDAAVEPSVAKTKMPDSPVAGRAT
VLIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLNKPVNDLSRGALVEDIVNTVAITAIQAQGDR

Sequences:

>Translated_704_residues
MSLMRQAVRVPDQTDSRVSAIYVASPEGDTGKSTIALGLLDRLTATAPRVGVFRPITRSGPARDYILELLLAHSTAGLTY
EDSVGVTYHQLHEDPDSALADIVDRFHRVADRCDVVLIVGSDYTDVASPSELSMNARIAANLGAPVVLAVKARGRTPDDV
VQVVEVCLDEIAAQHAYTAAVVANRCDPDQLTEVREALKRDGAPQVYVLPEEPLLVAPSVAELRDAVDGSMVSGDESLLD
REALDVLVAGMTAEHVLERLTEGVTVVTPGDRSDVVLAVVSAHAAEGFPSLSSIILNGGLELHPSIAKLVAGLGLRLPIV
ATGYGTFETASRVAGTRGRVTAASVRKIDTALTLMETHVDTAELLSRLAIPIPTVVTPQMFTYQLLDQARSDRKRIVLPE
GDDDRILKAAGRLLQRGVADLTILGEEGPVRARAAELGVDLAAATVLDPRTSELCDQFAEQYAELRRHKGVTVEQAREII
HDVSYFGTMLVHNDMVDGMVSGAAHTTAHTVRPAFEIIKTLPDVSTVSSIFLMCLADRVLAYGDCAIVPDPTAEQLADIA
ISSARTAAQFGIEPRVAMLSYSTGTSGTGADVEKVREATDLVHKREPDLLVEGPIQYDAAVEPSVAKTKMPDSPVAGRAT
VLIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLNKPVNDLSRGALVEDIVNTVAITAIQAQGDR
>Mature_703_residues
SLMRQAVRVPDQTDSRVSAIYVASPEGDTGKSTIALGLLDRLTATAPRVGVFRPITRSGPARDYILELLLAHSTAGLTYE
DSVGVTYHQLHEDPDSALADIVDRFHRVADRCDVVLIVGSDYTDVASPSELSMNARIAANLGAPVVLAVKARGRTPDDVV
QVVEVCLDEIAAQHAYTAAVVANRCDPDQLTEVREALKRDGAPQVYVLPEEPLLVAPSVAELRDAVDGSMVSGDESLLDR
EALDVLVAGMTAEHVLERLTEGVTVVTPGDRSDVVLAVVSAHAAEGFPSLSSIILNGGLELHPSIAKLVAGLGLRLPIVA
TGYGTFETASRVAGTRGRVTAASVRKIDTALTLMETHVDTAELLSRLAIPIPTVVTPQMFTYQLLDQARSDRKRIVLPEG
DDDRILKAAGRLLQRGVADLTILGEEGPVRARAAELGVDLAAATVLDPRTSELCDQFAEQYAELRRHKGVTVEQAREIIH
DVSYFGTMLVHNDMVDGMVSGAAHTTAHTVRPAFEIIKTLPDVSTVSSIFLMCLADRVLAYGDCAIVPDPTAEQLADIAI
SSARTAAQFGIEPRVAMLSYSTGTSGTGADVEKVREATDLVHKREPDLLVEGPIQYDAAVEPSVAKTKMPDSPVAGRATV
LIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLNKPVNDLSRGALVEDIVNTVAITAIQAQGDR

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0280

COG function: function code C; Phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=718, Percent_Identity=38.3008356545961, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1788800, Length=311, Percent_Identity=39.871382636656, Blast_Score=209, Evalue=7e-55,
Organism=Escherichia coli, GI1788806, Length=336, Percent_Identity=31.8452380952381, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 74880; Mature: 74749

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMRQAVRVPDQTDSRVSAIYVASPEGDTGKSTIALGLLDRLTATAPRVGVFRPITRSG
CCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PARDYILELLLAHSTAGLTYEDSVGVTYHQLHEDPDSALADIVDRFHRVADRCDVVLIVG
CHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEC
SDYTDVASPSELSMNARIAANLGAPVVLAVKARGRTPDDVVQVVEVCLDEIAAQHAYTAA
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVANRCDPDQLTEVREALKRDGAPQVYVLPEEPLLVAPSVAELRDAVDGSMVSGDESLLD
HHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHCCCCCCCCHHHHH
REALDVLVAGMTAEHVLERLTEGVTVVTPGDRSDVVLAVVSAHAAEGFPSLSSIILNGGL
HHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCEEEEEEHHHHHCCCCHHHHHHHCCCC
ELHPSIAKLVAGLGLRLPIVATGYGTFETASRVAGTRGRVTAASVRKIDTALTLMETHVD
EECHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCC
TAELLSRLAIPIPTVVTPQMFTYQLLDQARSDRKRIVLPEGDDDRILKAAGRLLQRGVAD
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCC
LTILGEEGPVRARAAELGVDLAAATVLDPRTSELCDQFAEQYAELRRHKGVTVEQAREII
EEEECCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
HDVSYFGTMLVHNDMVDGMVSGAAHTTAHTVRPAFEIIKTLPDVSTVSSIFLMCLADRVL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AYGDCAIVPDPTAEQLADIAISSARTAAQFGIEPRVAMLSYSTGTSGTGADVEKVREATD
HCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
LVHKREPDLLVEGPIQYDAAVEPSVAKTKMPDSPVAGRATVLIFPDLNTGNNTYKAVQRS
HHHCCCCCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHC
AGAIAIGPVLQGLNKPVNDLSRGALVEDIVNTVAITAIQAQGDR
CCCEEEHHHHHHCCCCHHHHHCCHHHHHHHHHHHHEEEECCCCC
>Mature Secondary Structure 
SLMRQAVRVPDQTDSRVSAIYVASPEGDTGKSTIALGLLDRLTATAPRVGVFRPITRSG
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PARDYILELLLAHSTAGLTYEDSVGVTYHQLHEDPDSALADIVDRFHRVADRCDVVLIVG
CHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEC
SDYTDVASPSELSMNARIAANLGAPVVLAVKARGRTPDDVVQVVEVCLDEIAAQHAYTAA
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVANRCDPDQLTEVREALKRDGAPQVYVLPEEPLLVAPSVAELRDAVDGSMVSGDESLLD
HHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHCCCCCCCCHHHHH
REALDVLVAGMTAEHVLERLTEGVTVVTPGDRSDVVLAVVSAHAAEGFPSLSSIILNGGL
HHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCEEEEEEHHHHHCCCCHHHHHHHCCCC
ELHPSIAKLVAGLGLRLPIVATGYGTFETASRVAGTRGRVTAASVRKIDTALTLMETHVD
EECHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCC
TAELLSRLAIPIPTVVTPQMFTYQLLDQARSDRKRIVLPEGDDDRILKAAGRLLQRGVAD
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCC
LTILGEEGPVRARAAELGVDLAAATVLDPRTSELCDQFAEQYAELRRHKGVTVEQAREII
EEEECCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
HDVSYFGTMLVHNDMVDGMVSGAAHTTAHTVRPAFEIIKTLPDVSTVSSIFLMCLADRVL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AYGDCAIVPDPTAEQLADIAISSARTAAQFGIEPRVAMLSYSTGTSGTGADVEKVREATD
HCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
LVHKREPDLLVEGPIQYDAAVEPSVAKTKMPDSPVAGRATVLIFPDLNTGNNTYKAVQRS
HHHCCCCCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHC
AGAIAIGPVLQGLNKPVNDLSRGALVEDIVNTVAITAIQAQGDR
CCCEEEHHHHHHCCCCHHHHHCCHHHHHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]