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The map label for this gene is ackA [H]

Identifier: 108797518

GI number: 108797518

Start: 596228

End: 597427

Strand: Direct

Name: ackA [H]

Synonym: Mmcs_0538

Alternate gene names: 108797518

Gene position: 596228-597427 (Clockwise)

Preceding gene: 108797517

Following gene: 108797519

Centisome position: 10.45

GC content: 67.42

Gene sequence:

>1200_bases
ATGACCCGCACAGTGCTCGTGCTCAACTCCGGGTCCTCGTCGCTGAAATTCCAACTGCTCGAACCGGACTCCGGGGCCTC
ACTGGCCGACGGGATCGTCGAGCGCATCGGTGAGGATTCGTCGTCGGCGAGCCTGGTGTGCGGCGAGCGGGAGGTCACGC
ACAGCGAGCGGGTACCCGACCACGAGGCCGCGCTACGTACGGCATACGGCCTGTTCGACGAGGCCGGCGCCGAATTGGGC
AGCGTCGGTCTCGTGGCGGTCGGGCACCGCGTCGTGCATGGTGGGCCCGATCTCTACCAGCCGACGCTGATCGACGACGC
GTTGGTCGACACGCTCGAGAGCCTGGCCCCGTTGGCGCCTCTGCACAACCCGCCCGCGGTCCTCGGCATACGCGGGGCTC
GTAAGGCCTTCCCGGACCTGCCCCACGTCGCGGTGTTCGACACCGCCTACTTCCACGACCTACCGGTTGCGGCAGCCACA
TACGCGATCGACCGGGACCTCTCCGAGCAGTGGCACATCCGGCGTTACGGGTTTCACGGCACCTCACACCAGTACGTCAG
TGAGCAGGCGGCGCTGTTCCTCGACGTCCCGCTGTCGTCGCTCAGCCAGATCGTGTTGCACCTCGGCAACGGAGCGTCGG
CGTCGGCGATCCTCGGCGGCCGCCCGATCGACACCTCGATGGGCCTGACGCCGATGGAGGGTCTGGTGATGGGCACCCGA
TCCGGCGACGTCGACCCGGGAGTGCTCGTATACCTCTGGCGCACAGCGGGAATGAGCGTCGACGAGATCGAGACGATGCT
CAACAAGCGGTCCGGGGTCCGTGGTCTCGGCGGTGAGATCGACTTCCGGGTGCTGCACCAGCGGATCGAAAGCGGTGACG
AATCCGACCGGGAGAACGCGCAACTGGCCTACGACGTGTACATCCACCGGCTGCGGAAGTACATCGGCGCGTACCTCGCG
CTGCTGGGGAGCACCGACGTGATCGTCTTCACCGCAGGTGTGGGCGAAAACGACGCCGCCGTGCGACGCGACGCGCTGTC
GGGCATGGGACGGCTGGGCATCGAGTTGGACGAGCATCTCAACGAGAGCCCGTCGCACACGGCGCGGCGCATCTCGGCGG
AGACGTCGCCCACCACGGTGCTCGTCATCCCCACCAACGAGGAGTTGGCGATCGCCCGGGCGTGCGTGGAGGTCATCTGA

Upstream 100 bases:

>100_bases
AGGGGCTCAACAAACCGGTCAACGACCTGTCACGCGGTGCGTTGGTAGAGGACATCGTCAACACGGTCGCGATCACCGCG
ATCCAGGCCCAGGGAGATCG

Downstream 100 bases:

>100_bases
CGATCAAAGATGATGACCGCAAACCCGCGAGATTCGCGCGGAGTTCGGCATAGGATGCGCTGATGGTATTCGGGGGGATC
ACCGGGTGGGCGGAGTGCCC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPDHEAALRTAYGLFDEAGAELG
SVGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAPLHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPVAAAT
YAIDRDLSEQWHIRRYGFHGTSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTR
SGDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENAQLAYDVYIHRLRKYIGAYLA
LLGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHLNESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI

Sequences:

>Translated_399_residues
MTRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPDHEAALRTAYGLFDEAGAELG
SVGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAPLHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPVAAAT
YAIDRDLSEQWHIRRYGFHGTSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTR
SGDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENAQLAYDVYIHRLRKYIGAYLA
LLGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHLNESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI
>Mature_398_residues
TRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPDHEAALRTAYGLFDEAGAELGS
VGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAPLHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPVAAATY
AIDRDLSEQWHIRRYGFHGTSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTRS
GDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENAQLAYDVYIHRLRKYIGAYLAL
LGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHLNESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=408, Percent_Identity=42.6470588235294, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI145693184, Length=393, Percent_Identity=39.1857506361323, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 42761; Mature: 42630

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPD
CCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHCCCC
HEAALRTAYGLFDEAGAELGSVGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAP
HHHHHHHHHHHHHHHCCCCCCCCEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
LHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPVAAATYAIDRDLSEQWHIRRYGFHG
CCCCCCEEEECCHHHCCCCCCCEEEECHHHHHCCCHHHHHHHHHCCCCHHHCEEEECCCC
TSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTR
CCHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECC
SGDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENA
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
QLAYDVYIHRLRKYIGAYLALLGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHC
NESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI
CCCCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHC
>Mature Secondary Structure 
TRTVLVLNSGSSSLKFQLLEPDSGASLADGIVERIGEDSSSASLVCGEREVTHSERVPD
CEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHCCCC
HEAALRTAYGLFDEAGAELGSVGLVAVGHRVVHGGPDLYQPTLIDDALVDTLESLAPLAP
HHHHHHHHHHHHHHHCCCCCCCCEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
LHNPPAVLGIRGARKAFPDLPHVAVFDTAYFHDLPVAAATYAIDRDLSEQWHIRRYGFHG
CCCCCCEEEECCHHHCCCCCCCEEEECHHHHHCCCHHHHHHHHHCCCCHHHCEEEECCCC
TSHQYVSEQAALFLDVPLSSLSQIVLHLGNGASASAILGGRPIDTSMGLTPMEGLVMGTR
CCHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECC
SGDVDPGVLVYLWRTAGMSVDEIETMLNKRSGVRGLGGEIDFRVLHQRIESGDESDRENA
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
QLAYDVYIHRLRKYIGAYLALLGSTDVIVFTAGVGENDAAVRRDALSGMGRLGIELDEHL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHC
NESPSHTARRISAETSPTTVLVIPTNEELAIARACVEVI
CCCCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA