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The map label for this gene is tig

Identifier: 108763895

GI number: 108763895

Start: 2340519

End: 2341796

Strand: Direct

Name: tig

Synonym: MXAN_2013

Alternate gene names: 108763895

Gene position: 2340519-2341796 (Clockwise)

Preceding gene: 108760288

Following gene: 108762291

Centisome position: 25.61

GC content: 66.35

Gene sequence:

>1278_bases
ATGAAGGTCCAGGTCGAGGAGCTTTCTCCCATTGAGAAGAAGCTCTCCATCGAGGTCGACAATGCCCGCGTGGCGGAGGA
GCTGTCCCGCGCGTACTCCAACCTGGGCCGCCAGGTGCGGCTGCCGGGGTTCCGTCAGGGCAAGGTGCCTCGCCGCATCC
TGGAGCAGCGCTTCCGTGACCAGGTAGAGGACGAGGTCATCCAGCGCGTGGTGCAGAGCGCGTACGTGGAGGCCATCCGC
GAGCACAACGTGGAGGTCGTCGCCACGCCGCAGGTGACCAACTCCGGCCTCAAGCCCAACACCCCGTTCACCTTCGAGGC
TCGCGTCGAGGTGAAGCCCAAGGTGGAGGCCAAGGACTACGTCGAGCTGCCGCTGACGAAGTCCGACACCGCCGTCACCG
ACGAGCAGGTGAACGAGCAGCTGGAGCGCATGCGCCAGTCGATGGCCCGGCTGGAGCCCGTCACCGACCGCGACACCGCC
GCCTCCGGCGACTACGTCACCGTGGACTTCGACGCCACCGTGGACGGCCAGCCGTTCGCGGGCAGCAAGGCGGAGGGCAT
CACCGTGCAGGTGCAGCCCGGTGAGCTGGTGGAGTCCAAGATTGCCGCCCTGGAGGGCGTGAAGGTCGGCGAGTCCAAGG
ACATCGACTACGCCTTCCCGCAGGAGTACCGGGTGGAGGAGGTGCGCGGAAAGACGGCGCGCTTCCACATCACGCTCAAG
GGCGTGCAGAAGGAAATCGTCCCCGAGCTGAACGACGACTTCGCCAAGCAGTCGGGCGTCGCCCAATCCATTGACGAGCT
GCGCACCAAGCTCCGTGAGGACATGGAGAAGGCGCGCAAGTCCCAGGTGGAGGGCGAGGAGCGTGAGGCGCTGATGAAGG
CGCTGCTGGAGCGCAACACCTTCGACGTGCCCCGCGCCATGGTGGAGCGGGCCATGGACTCCATGCTGCGCGGCGCGCTG
CAGCAGCTCCAGCGCTCCGGTGTGGACCCCCGCCAGCTGAACCTGGACTTCAACCGTCTGCGCGAAGACATGCGCGAGAA
GGCCCTCCAGGAAGTGAAGGGCACGCTGCTCTTCGAGTCCATCGCTCAGAAGGAGGGCATCCAGGCCTCCGACGCGGACG
TGGACGCCCGCATCGAGCAGCTCGCCAACGAGGCGGGCCAGCCGGTCGCCGTGGTGCAGAAGTACTTCAAGGGCGCCGAC
GAGCGGCTCGGGTTGTCTCTCCGACTCCGGGAGGAAAAGACGATTGAATTCCTGAGGAGCCGGGCGAAGTATTCGTAA

Upstream 100 bases:

>100_bases
GTTGACCCGTTCGTGCCTATCCCCTAAAGGCGCACGTCCCACTTTTCCGGCACCGCCCGAAACGACTGATTGTCCGGCGG
CGGTGGCGAGCGAGGCCCGC

Downstream 100 bases:

>100_bases
GGTTCCCTCACCGAGGTCGACATGCCCTTCATGCCCGTTCCCTACGTCATCGAGCAGACCCACCGGGGTGAGCGCTCGTA
CGACATCTACAGCCGGCTCC

Product: trigger factor

Products: peptidylproline (omega=0)

Alternate protein names: TF

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKVQVEELSPIEKKLSIEVDNARVAEELSRAYSNLGRQVRLPGFRQGKVPRRILEQRFRDQVEDEVIQRVVQSAYVEAIR
EHNVEVVATPQVTNSGLKPNTPFTFEARVEVKPKVEAKDYVELPLTKSDTAVTDEQVNEQLERMRQSMARLEPVTDRDTA
ASGDYVTVDFDATVDGQPFAGSKAEGITVQVQPGELVESKIAALEGVKVGESKDIDYAFPQEYRVEEVRGKTARFHITLK
GVQKEIVPELNDDFAKQSGVAQSIDELRTKLREDMEKARKSQVEGEEREALMKALLERNTFDVPRAMVERAMDSMLRGAL
QQLQRSGVDPRQLNLDFNRLREDMREKALQEVKGTLLFESIAQKEGIQASDADVDARIEQLANEAGQPVAVVQKYFKGAD
ERLGLSLRLREEKTIEFLRSRAKYS

Sequences:

>Translated_425_residues
MKVQVEELSPIEKKLSIEVDNARVAEELSRAYSNLGRQVRLPGFRQGKVPRRILEQRFRDQVEDEVIQRVVQSAYVEAIR
EHNVEVVATPQVTNSGLKPNTPFTFEARVEVKPKVEAKDYVELPLTKSDTAVTDEQVNEQLERMRQSMARLEPVTDRDTA
ASGDYVTVDFDATVDGQPFAGSKAEGITVQVQPGELVESKIAALEGVKVGESKDIDYAFPQEYRVEEVRGKTARFHITLK
GVQKEIVPELNDDFAKQSGVAQSIDELRTKLREDMEKARKSQVEGEEREALMKALLERNTFDVPRAMVERAMDSMLRGAL
QQLQRSGVDPRQLNLDFNRLREDMREKALQEVKGTLLFESIAQKEGIQASDADVDARIEQLANEAGQPVAVVQKYFKGAD
ERLGLSLRLREEKTIEFLRSRAKYS
>Mature_425_residues
MKVQVEELSPIEKKLSIEVDNARVAEELSRAYSNLGRQVRLPGFRQGKVPRRILEQRFRDQVEDEVIQRVVQSAYVEAIR
EHNVEVVATPQVTNSGLKPNTPFTFEARVEVKPKVEAKDYVELPLTKSDTAVTDEQVNEQLERMRQSMARLEPVTDRDTA
ASGDYVTVDFDATVDGQPFAGSKAEGITVQVQPGELVESKIAALEGVKVGESKDIDYAFPQEYRVEEVRGKTARFHITLK
GVQKEIVPELNDDFAKQSGVAQSIDELRTKLREDMEKARKSQVEGEEREALMKALLERNTFDVPRAMVERAMDSMLRGAL
QQLQRSGVDPRQLNLDFNRLREDMREKALQEVKGTLLFESIAQKEGIQASDADVDARIEQLANEAGQPVAVVQKYFKGAD
ERLGLSLRLREEKTIEFLRSRAKYS

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=427, Percent_Identity=28.5714285714286, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_MYXXD (Q1DAT1)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630242.1
- ProteinModelPortal:   Q1DAT1
- STRING:   Q1DAT1
- GeneID:   4107656
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2013
- TIGR:   MXAN_2013
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   YIKEKAF
- PhylomeDB:   Q1DAT1
- ProtClustDB:   CLSK946629
- BioCyc:   MXAN246197:MXAN_2013-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: 5.2.1.8

Molecular weight: Translated: 48092; Mature: 48092

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50059 FKBP_PPIASE; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVQVEELSPIEKKLSIEVDNARVAEELSRAYSNLGRQVRLPGFRQGKVPRRILEQRFRD
CCEEHHHCCCHHHHHEEEECHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHH
QVEDEVIQRVVQSAYVEAIREHNVEVVATPQVTNSGLKPNTPFTFEARVEVKPKVEAKDY
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
VELPLTKSDTAVTDEQVNEQLERMRQSMARLEPVTDRDTAASGDYVTVDFDATVDGQPFA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
GSKAEGITVQVQPGELVESKIAALEGVKVGESKDIDYAFPQEYRVEEVRGKTARFHITLK
CCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEH
GVQKEIVPELNDDFAKQSGVAQSIDELRTKLREDMEKARKSQVEGEEREALMKALLERNT
HHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
FDVPRAMVERAMDSMLRGALQQLQRSGVDPRQLNLDFNRLREDMREKALQEVKGTLLFES
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IAQKEGIQASDADVDARIEQLANEAGQPVAVVQKYFKGADERLGLSLRLREEKTIEFLRS
HHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCEEEECHHHHHHHHHH
RAKYS
HCCCC
>Mature Secondary Structure
MKVQVEELSPIEKKLSIEVDNARVAEELSRAYSNLGRQVRLPGFRQGKVPRRILEQRFRD
CCEEHHHCCCHHHHHEEEECHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHH
QVEDEVIQRVVQSAYVEAIREHNVEVVATPQVTNSGLKPNTPFTFEARVEVKPKVEAKDY
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
VELPLTKSDTAVTDEQVNEQLERMRQSMARLEPVTDRDTAASGDYVTVDFDATVDGQPFA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
GSKAEGITVQVQPGELVESKIAALEGVKVGESKDIDYAFPQEYRVEEVRGKTARFHITLK
CCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEH
GVQKEIVPELNDDFAKQSGVAQSIDELRTKLREDMEKARKSQVEGEEREALMKALLERNT
HHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
FDVPRAMVERAMDSMLRGALQQLQRSGVDPRQLNLDFNRLREDMREKALQEVKGTLLFES
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IAQKEGIQASDADVDARIEQLANEAGQPVAVVQKYFKGADERLGLSLRLREEKTIEFLRS
HHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCEEEECHHHHHHHHHH
RAKYS
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (omega=180)

Specific reaction: peptidylproline (omega=180) = peptidylproline (omega=0)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA